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D-PANTOTHENIC ACID

CAS No.
79-83-4
Chemical Name:
D-PANTOTHENIC ACID
Synonyms
PANTOTHENATE;Pantothenic;pantothenicacid;(R)-Pantothenate;(R)-3-(2,4-Dihydroxy-3,3-diMethylbutanaMido)propanoic acid;D-VITAMIN B(5);Ca pantothenaat;d-pantothenicaci;D-PANTOTHENIC ACID;(R)-pantothenicaci
CBNumber:
CB7716522
Molecular Formula:
C9H17NO5
Molecular Weight:
219.24
MDL Number:
MFCD00020513
MOL File:
79-83-4.mol
MSDS File:
SDS
Last updated:2024-03-28 16:55:20

D-PANTOTHENIC ACID Properties

Melting point 178-179℃
alpha D25 +37.5°
Boiling point 360.05°C (rough estimate)
Density 1.266
refractive index 1.4315 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
pka 4.30±0.10(Predicted)
form Oil to Gel
color Colourless
Stability Hygroscopic
LogP -0.856 (est)
FDA 21 CFR 101.9; 104.20; 107.10; 107.100; 310.545
NCI Dictionary of Cancer Terms pantothenic acid
FDA UNII 19F5HK2737
EPA Substance Registry System D-Pantothenic acid (79-83-4)

SAFETY

Risk and Safety Statements

Toxicity LD50 intraperitoneal in mouse: 1443mg/kg

D-PANTOTHENIC ACID price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 462022 Pantothenic Acid 79-83-4 1g $340 2021-12-16 Buy
TRC P190305 PantothenicAcid(TechnicalGrade,ContainsLactone) 79-83-4 2.5g $1115 2021-12-16 Buy
American Custom Chemicals Corporation INB0000861 D-PANTOTHENIC ACID 95.00% 79-83-4 50MG $1491.68 2021-12-16 Buy
American Custom Chemicals Corporation INB0000861 D-PANTOTHENIC ACID 95.00% 79-83-4 200MG $2344.65 2021-12-16 Buy
Medical Isotopes, Inc. 41875 PantothenicAcid 79-83-4 250g $675 2021-12-16 Buy
Product number Packaging Price Buy
462022 1g $340 Buy
P190305 2.5g $1115 Buy
INB0000861 50MG $1491.68 Buy
INB0000861 200MG $2344.65 Buy
41875 250g $675 Buy

D-PANTOTHENIC ACID Chemical Properties,Uses,Production

Physical properties

Pantothenic acid is composed of β-alanine joined to 2,4-dihydroxy-3,3- dimethylbutyric acid via an amide linkage. The molecule has an asymmetric center, and only the R-enantiomer, usually called D-(+)pantothenic acid, is biologically active and occurs naturally. Appearance: pantothenic acid is a yellow, viscous oil. Its calcium and other salts, however, are colorless crystalline substances; calcium pantothenate is the main product of commerce. Solubility: neither form is soluble in organic solvents, but each is soluble in water and ethanol. Stability: aqueous solu tions of pantothenic acid are unstable when heated under acidic or alkaline conditions

Originator

Panto-250 , Bio-Tech Pharmacal

Uses

Pantothenic Acid is a member of the B complex vitamins; essential vitamin for the biosynthesis of coenzyme A in mammalian cells. Occurs ubiquitously in all animal and plant tissue. The richest common source is liver, but jelly of the queen bee contains 6 times as much as liver. Rice bran and molasses are other good sources.

Uses

Vitamin B5 is water-soluble. It is required for proper growth and maintenance of the body and is involved in body processes such as energy release from carbohydrates and metabolism of fatty acids. It is relatively stable through storage and is found in liver, eggs, and meat.

Uses

Labelled Pantothenic Acid

Definition

ChEBI: (R)-pantothenic acid is a pantothenic acid having R-configuration. It has a role as an antidote to curare poisoning, a human blood serum metabolite and a geroprotector. It is a vitamin B5 and a pantothenic acid. It is a conjugate acid of a (R)-pantothenate.

Manufacturing Process

Isobutylaldehyde reacted with formaldehyde in the presence potassium chromate as a result 2,2-dimethyl-3-hydroxy-propanal was obtained.
The 2,2-dimethyl-3-hydroxy-propanal was treated by sodium cyanide so 2,4dihydroxy-3,3-dimethyl-butironitrile was prepared.
The 2,4-dihydroxy-3,3-dimethyl-butironitrile was treated hydrochloric acid and D,L-3-hydroxy-4,4-dimethyl-dihydro-furan-2-one (D,L-pantolacton) was obtained. The racemic mixture of D- and L-pantolactons was a division of Dand L- isomers by the adding of α-phenylethylamine. So D-pantolacton was isolated.
Acrylic acid contacted with NH3and β-alanine was obtained.
D-Pantalacton reacted with β-alanine as a result 3-(2,4-dihydroxy-3,3dimethyl-butyrylamino)-propanoic acid was produced

brand name

Calpan (BASF); Pantholin (Lilly).

Therapeutic Function

Vitamin

Safety Profile

Moderately toxic by subcutaneous and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NOx.

137-08-6
79-83-4
Synthesis of D-PANTOTHENIC ACID from Calcium D-Pantothenate
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View Lastest Price from D-PANTOTHENIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
vitamin b5 pictures 2024-04-19 vitamin b5
79-83-4
US $45.00 / KG 10KG 99% 10000 kilograms/month Hebei Yime New Material Technology Co., Ltd.
D-PANTOTHENIC ACID pictures 2024-04-19 D-PANTOTHENIC ACID
79-83-4
US $55.00 / KG 1KG 99% 20t Hebei Yime New Material Technology Co., Ltd.
vitamin B5 Calcium D pantothenate pictures 2024-04-19 vitamin B5 Calcium D pantothenate
79-83-4
US $55.00 / KG 10KG 99% 1000kg Hebei Yime New Material Technology Co., Ltd.
  • vitamin b5 pictures
  • vitamin b5
    79-83-4
  • US $45.00 / KG
  • 99%
  • Hebei Yime New Material Technology Co., Ltd.
vitaminb5,pantothenicacid,pantothenate D-PANTOTHENIC ACID D-VITAMIN B(5) D.CALCIUM PANTOTHENATE USP/IP .beta.-Alanine, N-(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl- 3-[[(2R)-2,4-dihydroxy-3,3-dimethyl-butanoyl]amino]propanoic acid D-Pantothenic acid(Vitamin B5) Pantothenic acid, D- (8CI) β-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, (R)- β-Alanine, N-[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]- D-calcim pantothenate (VITAMIN B5,D-PANTOTHENIC ACID) USP GRADE Ca pantothenaat (+)-pantothenicacid (d,+)-n(alpha-gamma-dihydroxy-beta,beta-dimethylbutyryl)-beta-alanine 4-dihydroxy-3,3-dimethyl-1-oxobutyl)-n-((r)-beta-alanin chickantidermatitisfactor D(+)-N-(2,4-Dihy-droxy-3,3-dimethylbutyryl)-alanine d-pantothenicaci kyselinapantothenova N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-,(R)-.beta.-Alanine N-[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]-β-alanine (-)-3-[[(S)-2,4-Dihydroxy-3,3-dimethylbutyryl]amino]propionic acid (R)-N-(2,4-Dihydroxy-3,3-dimethylbutyryl)-beta-alanine 3-[(2R)-2,4-dihydroxy-3,3-diMethylbutanaMido]propanoic acid Pantothenic acid(pantothenate) (R)-Pantothenic acid D-Pantothenic acid Solution, 1000μg/mL (R)-pantothenicaci D-PANTOTHENIC ACID USP/EP/BP Pantothenic acid (Vitamin B5) Pantothenic PANTOTHENATE (R)-3-(2,4-Dihydroxy-3,3-diMethylbutanaMido)propanoic acid (R)-Pantothenate pantothenicacid (+)-pantothenicacid Ethanol,2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-,5-methylbenzenesulfonate Colesevelam Impurity 11 (R)-3-(2,4-Dihydroxy-3,3-dimethylbutanamido)propionic Acid 79-83-4 C1613C2H28D4CaN2O10 FEED ADDITIVES Aliphatics Chiral Reagents Intermediates & Fine Chemicals Isotope Labelled Compounds Pharmaceuticals Inhibitors 79-83-4