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(+/-)-MCN 5652

CAS No.
96795-89-0
Chemical Name:
(+/-)-MCN 5652
Synonyms
(-)-McN-5652Z;(-)-McN-5652-Z;(+/-)-MCN 5652;trans-McN-5652;(+/-)-MCN 5652;1,2,3,5,6,10bβ-Hexahydro-6α-[4-(methylthio)phenyl]pyrrolo[2,1-a]isoquinoline;(6S)-1,2,3,5,6,10bβ-Hexahydro-6β-(4-methylthiophenyl)pyrrolo[2,1-a]isoquinoline;trans-1,2,3,5,6,10b-hexahydro-6-<4-(methylthio)phenyl>pyrrolo<2,1-a>isoquinoline;(6R,10bS)-6-(4-methylsulfanylphenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline;(6R,10bS)-rel-1,2,3,5,6,10b-Hexahydro-6-[4-(methylthio)phenyl]-pyrrolo[2,1-a]isoquinoline
CBNumber:
CB7789155
Molecular Formula:
C19H21NS
Molecular Weight:
295.44
MDL Number:
MFCD09753376
MOL File:
96795-89-0.mol
Last updated:2023-05-18 11:31:11

(+/-)-MCN 5652 Properties

storage temp. Store at -20°C
solubility <14.77mg/ml in 1eq. HCl; <22.16mg/ml in DMSO
FDA UNII 21MT8QF2LI

(+/-)-MCN 5652 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M199410 (±)-Mcn5652 96795-89-0 25mg $295 2021-12-16 Buy
American Custom Chemicals Corporation API0009811 (+/-)-MCN 5652 95.00% 96795-89-0 5MG $503.29 2021-12-16 Buy
ApexBio Technology B6954 (6R,10bS)-6-(4-(methylthio)phenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline 96795-89-0 50mg $853 2021-12-16 Buy
ApexBio Technology B6954 (6R,10bS)-6-(4-(methylthio)phenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline 96795-89-0 10mg $203 2021-12-16 Buy
Product number Packaging Price Buy
M199410 25mg $295 Buy
API0009811 5MG $503.29 Buy
B6954 50mg $853 Buy
B6954 10mg $203 Buy

(+/-)-MCN 5652 Chemical Properties,Uses,Production

Uses

McN 5652, (+/-) is a 5-HT uptake inhibitor.

Definition

ChEBI: (6R,10bS)-6-[4-(methylthio)phenyl]-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline is a member of isoquinolines.

Biological Activity

Potent, high affinity serotonin re-uptake inhibitor that is selective in vivo . In vitro, displays moderate selectivity over noradrenalin and dopamine re-uptake (K i values are 0.68, 2.9 and 36.8 nM for inhibition of serotonin, noradrenalin and dopamine uptake respectively in rat brain synaptosomes). Potently potentiates 5-HT-induced effects in vivo following oral administration. Biological activity resides predominantly in (+)-enantiomer.

(+/-)-MCN 5652 Preparation Products And Raw materials

Raw materials

Preparation Products

(+/-)-MCN 5652 Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725 malulu@leyan.com China 40041 58
ApexBio Technology -- sales@apexbt.com United States 6254 58
(+/-)-MCN 5652 rel-(6R*,10bS*)-6α*-[4-(Methylthio)phenyl]-1,2,3,5,6,10bβ*-hexahydropyrrolo[2,1-a]isoquinoline trans-McN-5652 (-)-McN-5652Z (-)-McN-5652-Z 1,2,3,5,6,10bβ-Hexahydro-6α-[4-(methylthio)phenyl]pyrrolo[2,1-a]isoquinoline (6S)-1,2,3,5,6,10bβ-Hexahydro-6β-(4-methylthiophenyl)pyrrolo[2,1-a]isoquinoline (6R,10bS)-rel-1,2,3,5,6,10b-Hexahydro-6-[4-(methylthio)phenyl]-pyrrolo[2,1-a]isoquinoline (6R,10bS)-6-(4-methylsulfanylphenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline trans-1,2,3,5,6,10b-hexahydro-6-<4-(methylthio)phenyl>pyrrolo<2,1-a>isoquinoline Pyrrolo[2,1-a]isoquinoline, 1,2,3,5,6,10b-hexahydro-6-[4-(methylthio)phenyl]-, (6R,10bS)-rel- (+/-)-MCN 5652 96795-89-0