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3-Nitrophthalic anhydride

CAS No.
641-70-3
Chemical Name:
3-Nitrophthalic anhydride
Synonyms
1,3-Isobenzofurandione, 4-nitro-;3-Nitrophthalic Acid Anhydride;4-NITRO-ISOBENZOFURAN-1,3-DIONE;NSC 4134;NSC 27006;3-NitrophthaL;Pomalidomide INT;Apremilast Impurity 90;Pomalidomide Impurity 36;3-NITROPHTHALIC ANHYDRIDE
CBNumber:
CB8116378
Molecular Formula:
C8H3NO5
Molecular Weight:
193.11
MDL Number:
MFCD00005921
MOL File:
641-70-3.mol
MSDS File:
SDS
Last updated:2024-03-26 17:16:27

3-Nitrophthalic anhydride Properties

Melting point 163-165 °C (lit.)
Boiling point 329.3°C (rough estimate)
Density 1.6392 (rough estimate)
refractive index 1.4700 (estimate)
storage temp. Store below +30°C.
form Crystalline Powder
color Beige to yellow
Water Solubility MAY DECOMPOSE
Sensitive Moisture Sensitive
BRN 179963
CAS DataBase Reference 641-70-3(CAS DataBase Reference)
FDA UNII X2BXS9KCY2
NIST Chemistry Reference 3-Nitrophthalic anhydride(641-70-3)
EPA Substance Registry System 1,3-Isobenzofurandione, 4-nitro- (641-70-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
10-21
TSCA  Yes
HS Code  29173980
NFPA 704
1
2 1

3-Nitrophthalic anhydride price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.20903 3-Nitrophthalic anhydride for synthesis 641-70-3 25g $87.5 2024-03-01 Buy
Sigma-Aldrich 8.20903 3-Nitrophthalic anhydride for synthesis 641-70-3 100g $164 2024-03-01 Buy
Sigma-Aldrich 156884 3-Nitrophthalic anhydride 98% 641-70-3 5g $76.2 2024-03-01 Buy
Sigma-Aldrich 156884 3-Nitrophthalic anhydride 98% 641-70-3 25g $148.8 2024-03-01 Buy
TCI Chemical N0245 3-Nitrophthalic Anhydride >97.0%(GC)(T) 641-70-3 25g $33 2024-03-01 Buy
Product number Packaging Price Buy
8.20903 25g $87.5 Buy
8.20903 100g $164 Buy
156884 5g $76.2 Buy
156884 25g $148.8 Buy
N0245 25g $33 Buy

3-Nitrophthalic anhydride Chemical Properties,Uses,Production

Chemical Properties

Beige to yellow crystalline powder

Uses

An intermediate for the synthesis of a benzimidazole PARP inhibitor I (succinate salt) (ABT-472). Reactions with aminoquinazolinones yield phthalimidoquinazolinones.

Uses

4-Nitrophthalic Anhydride is an intermediate for the synthesis of the benzimidazole PARP inhibitor I, ABT-472. It reacts with aminoquinazolinones to yield phthalimidoquinazolinones.

Preparation

3-Nitrophthalic anhydride can be prepared by heating 3-nitrophthalic acid under various conditions and by the action of acetic anhydride, essentially as in the procedure described. The direct nitration of phthalic anhydride yields 3-nitrophthalic anhydride together with the isomeric 4-nitro compound.

Purification Methods

Crystallise it from *C6H6, *C6H6/pet ether, Me2CO, AcOH, or Ac2O (m 164-165o). Dry it at 100o. [Beilstein 17 III/IV 6149, 17/11 V 266.]

603-11-2
641-70-3
Synthesis of 3-Nitrophthalic anhydride from 3-Nitrophthalic acid
Global( 407)Suppliers
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Asia Chem I and E (Jiangsu) Co Ltd
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Hebei Kangcang new material Technology Co., LTD
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Capot Chemical Co.,Ltd.
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Jinan Finer Chemical Co., Ltd
+86-531-88989536 +86-15508631887 sales@finerchem.com China 2967 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58

View Lastest Price from 3-Nitrophthalic anhydride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Nitrophthalic anhydride pictures 2024-04-24 3-Nitrophthalic anhydride
641-70-3
US $9.00-80.00 / g 10g min99% 10 tons Hebei Kangcang new material Technology Co., LTD
3-Nitrophthalic anhydride pictures 2024-04-24 3-Nitrophthalic anhydride
641-70-3
US $62.79 / Kg/Drum 25Kg/Drum 98.00%HPLC 8.8tons/month Asia Chem I and E (Jiangsu) Co Ltd
3-Nitrophthalic anhydride pictures 2023-03-06 3-Nitrophthalic anhydride
641-70-3
US $10.70 / Kg/Bag 10g 99% 10000kg Hebei Guanlang Biotechnology Co,.LTD
1,3-Isobenzofurandione,4-nitro- 3-Isobenzofurandione,4-nitro-1 NSC 4134 3-Nitrophthalic anhydride, synthesis grade 4-Nitrobenzo[c]furan-1,3-dione, 4-Nitro-2-benzofuran-1,3-dione, 4-Nitroisobenzofuran-1,3-dione 3-Nitrophthalic anhydride,97% Phthalic anhydride, 3-nitro- (6CI,7CI,8CI) 3-Nitrophthalic anhydride 98% 3-Nitrophthalic anhydride98% The 3- nitrophthalicanhydridetwo 4-Nitro-2-benzofuran-1,3-dione 4-nitro-3-isobenzofurandione Phthalic anhydride, 3-nitro- NSC 27006 3-NITROPHTHALIC ANHYDRIDE 1-Amino-2-Indolinon (CIS) 4-Nitro-1,3-iso benzofurandione 3-NITROPHTHALIC ANHYDRIDE ,99+% 3-NitrophthaL Phthalic anhydride, 3-nitro- (8CI) 3-NitrophthalicAnhydride> 3-NITROPHTHALIC ANHYDRIDE FOR SYNTHESIS 1,3-Isobenzofurandione, 4-nitro- 4-NITRO-ISOBENZOFURAN-1,3-DIONE 3-Nitrophthalic Acid Anhydride Pomalidomide INT Pomalidomide Impurity 36 RSSYY(Perospirone Hydrochloride Hydrate)-9 3-Nitrophthalic anhydride?New Apremilast Impurity 90 641-70-3 C8H3NO5 O2NC6H3CO2O Organic Building Blocks Carbonyl Compounds Carboxylic Acid Anhydrides Building Blocks Anhydride Monomers Monomers Polymer Science Carbonyl Compounds Carboxylic Acid Anhydrides Organic Building Blocks Building Blocks Carbonyl Compounds Carboxylic Acid Anhydrides Chemical Synthesis Organic Building Blocks Amines Aromatics Intermediates Phthalic Acids, Esters and Derivatives Dyes intermediates