Pullulan

Pullulan Properties

Melting point	>248°C (dec.)
storage temp.	2-8°C
solubility	H₂O: 50 mg/mL, slightly hazy, colorless
form	Powder
color	White to Off-white
Odor	at 100.00?%. odorless
EWG's Food Scores	1
FDA UNII	8ZQ0AYU1TT
EPA Substance Registry System	Pullulan (9057-02-7)

SAFETY

Risk and Safety Statements

Safety Statements	24/25
WGK Germany	3
RTECS	UO5470000
F	3
TSCA	Yes
HS Code	29400090

Pullulan price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	P4516	Pullulan suitable for substrate for pullulanase	9057-02-7	1G	$91.2	2023-06-20	Buy
Sigma-Aldrich	P4516	Pullulan suitable for substrate for pullulanase	9057-02-7	5G	$310	2023-06-20	Buy
Sigma-Aldrich	P4516	Pullulan suitable for substrate for pullulanase	9057-02-7	25G	$1160	2023-06-20	Buy
Sigma-Aldrich	96351	Pullulan Standard Set Mp ~350 - 700′000 set of analytical standards, for GPC	9057-02-7	1KIT	$2740	2022-05-15	Buy
TCI Chemical	P0978	Pullulan	9057-02-7	25g	$60	2024-03-01	Buy

Product number	Packaging	Price	Buy
P4516	1G	$91.2	Buy
P4516	5G	$310	Buy
P4516	25G	$1160	Buy
96351	1KIT	$2740	Buy
P0978	25g	$60	Buy

Pullulan Chemical Properties,Uses,Production

Description

Pullulan is a water-soluble, linear homopolysaccharide of glucose that is produced extracellularly by certain strains of the Aureobasidium pullulans fungus. This polysaccharide possesses adhesive properties and can be utilized to create strong, compression moldings, fibers, and oxygen-impermeable films. In the food industry, pullulan films are frequently used as coating or packaging material for dried foods, as a binder for tobacco, plant fertilizers, and seed coatings, as a low-viscosity filler in sauces and beverages, as well as a stabilizer and binder in food pastes. Additionally, this polysaccharide is often used to halt fungal growth in food. As for pharmaceutical applications, pullulan is used as a denture adhesive and an ingredient in sugar-coated pharmaceutical compositions to prevent the development of brownish coloring. Finally, pullulan finds application in lotions, shampoos, and cosmetics.

Chemical Properties

It is a white, tasteless, and odorless non-crystalline powder that dissolves easily in water and dimethylformamide, but not in alcohol, ether, or oil. Its solution is viscous, stable, and neutral, with no gelling effect. The viscosity of the solution is the same as that of gum arabic, and it has a very good thickening effect of salt resistance, enzyme resistance, heat resistance, and pH value change resistance. It has strong film-forming properties, and the film formed after its aqueous solution is dried on a metal plate has strong gas barrier properties to oxygen and nitrogen. Moreover, it is suitable for making water-soluble edible films and is compatible with other water-soluble polymers.

Uses

Pullulan has been used in a study to assess bone tissue engineering. It has also been used in a study that investigated anti-fog applications.

Definition

pullulan: A water-soluble polysaccharidecomposed of glucose unitsthat are polymerized in such a wayas to make it viscous and impermeableto oxygen. Pullulan is used in adhesives, food packaging, andmoulded articles. It is derived fromthe fungus Aureobasidium pullulans.

Application

Pullulan is a hemocompatible, nonimmunogenic, and noncarcinogenic agent. In the food industry are mainly filler, edible, and tasteless polymers. Furthermore, in pharmaceuticals and electronics pullulan is used in tissue engineering, drug and gene delivery systems, as a coating agent, and as a film- and fiber-forming agent, due to its excellent physicochemical properties. Pullulan is the backbone of a polymeric system capable of forming hydrogels and nanogels. These systems show potential applications in the preparation of green smart materials, biomimetics, biosensors, artificial muscles, drug delivery systems, and chemical separations. Pullulan-based nanosystems can act as carriers of different drugs. It has been used as a carrier for oral, nasal, and lung transmucosal drug delivery systems because it is not attacked by the digestive enzymes in the human gut[3-4].

Production Methods

Pullulan is produced by fermentation from a food-grade hydrolyzed search with a non-toxin-producing strain of Aureobasidium pullulans. After fermentation, the fungal biomass is removed by microfiltration, the filtrate is heat-sterilized, and pigments and other impurities are removed by adsorption and ion exchange chromatography. The product contains not less than 90% glucan on a dried basis. The main impurities from the starting material are mono-, di-, and oligosaccharides. The average relative molecular mass of pullulan varies considerably depending on the conditions of the culture. A commercially available product has an average relative molecular mass of 200 000 Da.

Biological Functions

Pullulan is a polysaccharide polymer that is derived from the Aureobasidium pullulans yeast and consists of D-Maltotriose units. It is used as a binder and film former in a variety of formulation categories (skin, make-up, and hair). Pullulan has been used in a study to assess bone tissue engineering. Addition of pullulan has improved the elongation at break of gelatin based edible film when the amount was 50% (wt. %).

General Description

Pullulan Standards are mostly used to obtain molecular mass distribution of cellulosic samples. It mainly consists of polymaltotriose units linked together by α-(1→6) linkages. Pullulan is a biodegradable polysaccharide made by yeast fermentation, originally developed in Japan. Its adhesive and oxygen impermeable properties enable it to be used to coat pharmaceutical products. It is water soluble, odorless, and edible.

Structure and conformation

Pullulan is a naturally occurring, fungal polysaccharide produced by fermentation of liquefied corn starch by Aureobasidium pullulans, a ubiquitous yeast-likefungus. It has a linear structure consisting predominantly of repeating maltotriose units, which are made up of three o-1,4-linked glucose molecules linked by a-1,6-glycosidic bonds. The maltotriose units are interspersed with about 6% maltotetraose units consisting of four o-1,4-linked glucose molecules; rarely, branch points occur, at which poly-maltotriose side chains are attached to the main chain by a 1,3-glycosidic bond.

References

[1] Timothy D. Leathers, Biopolymers Online, 2005,
[2] Ram S. Singh, Gaganpreet K. Saini and John F. Kennedy, Pullulan: Microbial sources, production and applications, Carbonhydrate Polymers, 2008, vol. 73, 515-531.
[3] Nasrollahzadeh M, et al. Green Nanotechnology. Interface Science and Technology, 2019; 28: 145-198.
[4] Narayanaswamy R, et al. Basics to different imaging techniques, different nanobiomaterials for image enhancement. Nanobiomaterials in Medical Imaging, 2016; 101-129.

Pullulan Preparation Products And Raw materials

Raw materials

D-(+)-Maltose monohydrate Hydrolyzate

Preparation Products

Pullulan Suppliers

Global( 336)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Across Biotech Jinan Co LTD	+8613031735486	frank@acrossbiotech.com	China	105	58
Wuhan BJM Pharm Inc	+86-027-5234-1919 +8613545198479	sales03@benjaminpharmchem.com	China	671	58
Leading Chemical and Trading Co.,Ltd	+8615669938129	sales@leadingchemical.com	China	120	58
Hebei Yime New Material Technology Co., Ltd.	+86-66697723 +86-17703311139	admin@china-yime.com	China	563	58
Wuhan Quanjinci New Material Co.,Ltd.	+8615271838296	kyra@quanjinci.com	China	1532	58
Hebei Jingbo New Material Technology Co., Ltd	+8619931165850	hbjbtech@163.com	China	1000	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15371	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Hubei XinRunde Chemical Co., Ltd.	+8615102730682	bruce@xrdchem.cn	CHINA	566	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58

Supplier	Advantage
Across Biotech Jinan Co LTD	58
Wuhan BJM Pharm Inc	58
Leading Chemical and Trading Co.,Ltd	58
Hebei Yime New Material Technology Co., Ltd.	58
Wuhan Quanjinci New Material Co.,Ltd.	58
Hebei Jingbo New Material Technology Co., Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hubei XinRunde Chemical Co., Ltd.	55
career henan chemical co	58

View Lastest Price from Pullulan manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-18	pullulan 9057-02-7	US $15.00 / kg	1kg	99.912%	10ton	Ouhuang Engineering Materials (Hubei) Co., Ltd
2024-04-16	Pullulan 9057-02-7	US $40.00-30.00 / kg	1kg	99%	5000kg/week	Hebei Yime New Material Technology Co., Ltd.
2023-12-29	Pullulan 9057-02-7	US $8.00 / kg	1kg	99%	200000	Hebei Jingbo New Material Technology Co., Ltd

pullulan
9057-02-7
US $15.00 / kg
99.912%
Ouhuang Engineering Materials (Hubei) Co., Ltd

Pullulan
9057-02-7
US $40.00-30.00 / kg
99%
Hebei Yime New Material Technology Co., Ltd.

Pullulan
9057-02-7
US $8.00 / kg
99%
Hebei Jingbo New Material Technology Co., Ltd

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