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Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate

Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate structure

CAS No.: 179688-26-7

Chemical Name:: Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate

Synonyms: ERLOTINIBIM-B;ERLOTINIBINT-C;Erlotinib Impurity 6;Erlotinib interMidiate III;Erlotinib Hydrochloride iMpurity 25;Ethyl 4,5-Bis(2-Methoxyethoxy)-2-Nitrobe;4,5-bis(2-methoxyethoxy)-2-nitrobenzoate;Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate;Methyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate;4,5-Bis(2-methoxyethoxy)-2-nitrobenzoic acid ethyl ester

CBNumber:: CB81504004

Molecular Formula:: C15H21NO8

Molecular Weight:: 343.33

MDL Number:: MFCD06797662

MOL File:: 179688-26-7.mol

Last updated:2023-04-23 13:52:06

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Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Properties

Boiling point	467.8±45.0 °C(Predicted)
Density	1.215
storage temp.	Refrigerator
solubility	DMSO (Slightly), Ethyl Acetate (Slightly)
form	Oil
color	Yellow
CAS DataBase Reference	179688-26-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319
Precautionary statements	P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	E900080	Ethyl4,5-Bis(2-methoxyethoxy)-2-nitrobenzoate	179688-26-7	250mg	$65	2021-12-16	Buy
Matrix Scientific	094640	Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 95+%	179688-26-7	1g	$103	2021-12-16	Buy
AK Scientific	B654	Ethyl4,5-bis(2-methoxyethoxy)-2-nitrobenzoate	179688-26-7	250mg	$240	2021-12-16	Buy
Matrix Scientific	094640	Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 95+%	179688-26-7	5g	$357	2021-12-16	Buy
AK Scientific	J11301	ErlotinibImpurity6	179688-26-7	25mg	$60	2021-12-16	Buy

Product number	Packaging	Price	Buy
E900080	250mg	$65	Buy
094640	1g	$103	Buy
B654	250mg	$240	Buy
094640	5g	$357	Buy
J11301	25mg	$60	Buy

Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Chemical Properties,Uses,Production

Uses

Ethyl 4,5-Bis(2-methoxyethoxy)-2-nitrobenzoate is used in the syntheses of 4-(indol-3-yl)quinazolines as epidermal growth factor receptor tyrosine kinase inhibitors. It is also used to prepare Erlotinib hydrochloride (E625000), a useful drug in treatment of non-?small-?cell lung cancer.

Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Suppliers

Global( 117)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2967	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Hubei Jusheng Technology Co.,Ltd.	58
Jinan Finer Chemical Co., Ltd	58
Accela ChemBio Inc.	58
Standardpharm Co. Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
Career Henan Chemica Co	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58

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4,5-Bis(2-methoxyethoxy)-2-nitrobenzoic acid ethyl ester Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Methyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Erlotinib interMidiate III Benzoic acid,4,5-bis(2-Methoxyethoxy)-2-nitro-, ethyl ester Erlotinib Impurity 6 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate ###179688-26-7 ERLOTINIBINT-C ERLOTINIBIM-B Ethyl 4,5-Bis(2-Methoxyethoxy)-2-Nitrobe Erlotinib Hydrochloride iMpurity 25 179688-26-7 C15H21NO8 Erlotinib INTERMEDIATES