ChemicalBook >> CAS DataBase List >>DIGITOXIGENIN
DIGITOXIGENIN
- CAS No.
- 143-62-4
- Chemical Name:
- DIGITOXIGENIN
- Synonyms
- echujetin;evonogenin;NSC 407806;THEVETIGENIN;cerberigenin;igitoxigenin;DIGITOXYGENIN;DIGITOXIGENIN;digitoxigenine;Digitoxigenin >
- CBNumber:
- CB8187462
- Molecular Formula:
- C23H34O4
- Molecular Weight:
- 374.51
- MDL Number:
- MFCD00003687
- MOL File:
- 143-62-4.mol
- MSDS File:
- SDS
Last updated:2023-08-23 18:01:39
| Melting point | 253-255 °C (dec.)(lit.) |
|---|---|
| Boiling point | 423.5°C (rough estimate) |
| alpha | D17 +19.1° (c = 1.36 in methanol) |
| Density | 1.0284 (rough estimate) |
| refractive index | 1.4433 (estimate) |
| storage temp. | Store at -20°C |
| solubility | DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml |
| form | powder to crystal |
| pka | 14.93±0.70(Predicted) |
| color | White to Almost white |
| Water Solubility | 11.24mg/L(30 ºC) |
| Merck | 14,3162 |
| BRN | 95448 |
| Stability | Hygroscopic |
| LogP | 2.640 |
| CAS DataBase Reference | 143-62-4(CAS DataBase Reference) |
| FDA UNII | S63WOD4VOL |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P405-P501 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25 | |||||||||
| Safety Statements | 45 | |||||||||
| RIDADR | UN 3462 6.1/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | FH4975000 | |||||||||
| HS Code | 2938.90.0000 | |||||||||
| HazardClass | 6.1(a) | |||||||||
| PackingGroup | II | |||||||||
| Toxicity | cat,LDLo,intravenous,254ug/kg (0.254mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITING,Journal of the American Pharmaceutical Association. Vol. 27, Pg. 189, 1938. | |||||||||
| NFPA 704 |
|
DIGITOXIGENIN price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D9404 | Digitoxigenin non-ionic | 143-62-4 | 10mg | $101 | 2024-03-01 | Buy |
| Sigma-Aldrich | D9404 | Digitoxigenin non-ionic | 143-62-4 | 100mg | $618 | 2024-03-01 | Buy |
| TCI Chemical | D0541 | Digitoxigenin >97.0%(HPLC) | 143-62-4 | 10mg | $219 | 2024-03-01 | Buy |
| Cayman Chemical | 18229 | Digitoxigenin ≥98% | 143-62-4 | 5mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 18229 | Digitoxigenin ≥98% | 143-62-4 | 10mg | $78 | 2024-03-01 | Buy |
DIGITOXIGENIN Chemical Properties,Uses,Production
Uses
Cardiotonic;Na+ K+ ATPase inhibitor
Definition
ChEBI: Digitoxigenin is a 5beta-cardenolide that is 5beta-cardanolide with hydroxy substituents at the 3beta- and 14beta-positions and double bond unsaturation at C(20)-C(22). It is a 3beta-hydroxy steroid and a 14beta-hydroxy steroid. It derives from a hydride of a 5beta-cardanolide.
Purification Methods
Dissolve digitoxigenin in EtOAc, wash it with H2O, dry it (Na2SO4), evaporate and recrystallise it from 40% aqueous EtOH or aqueous MeOH then EtOAc/Et2O. The UV has max at 218nm ( 14,500 M-1cm-1). The 3-acetate crystallises from Me2CO/Et2O with m 222-227o, [] D 20 +21o (c 1, CHCl3). [Wyss et al. Helv Chim Acta 43 644 1960, Cruz et al. J Org Chem 4 2 3580 1977, Beilstein 18 IV 1468.]
DIGITOXIGENIN Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 123)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3465 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
View Lastest Price from DIGITOXIGENIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-12 | DIGITOXIGENIN
143-62-4
|
US $0.00 / kg | 1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd |
-
- DIGITOXIGENIN
143-62-4
- US $0.00 / kg
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd
143-62-4(DIGITOXIGENIN)Related Search:
echujetin
evonogenin
3-beta,14-dihydroxy-5-beta,14-beta-card-20(22)-enolide
3β,14-dihydroxy-5β,20(22)-cardenolide
DIGITOXYGENIN
3β,14-Dihydroxy-5β,20(22)-cardenolide, 3,14,21-Trihydroxy-20(22)-norcholenic acid lactone, 5β,20(22)-Cardenolide-3β,14-diol, Digitoxigenin
3β,14-Dihydroxy-5β,20(22)-cardenolide, 3,14,21-Trihydroxy-20(22)-norcholenic acid lactone, 5β,20(22)-Cardenolide-3β,14-diol
THEVETIGENIN
3,14-dihydroxy-,(3-beta,5-beta)-card-20(22)-enolid
3-beta,14-dihydroxy-5-beta-card-20(22)-enolid
3-beta,14-dihydroxy-5-beta-card-20(22)-enolide
3-beta,14-dioxy-carden-(20:22)-olid
3-beta,14-dioxy-digen-(20:22)-olid
cardogenen-(20:22)-diol-(3-beta,14)
3β,14-Dihydroxy-5β,14β-card-20(22)-enolide
3β,14-Dihydroxy-5β-cardanolide-20(22)-ene
δ20:22-3,14,21-Trihydroxynorcholenic acid lactone
5β,20(22)-Cardenolide-3β
3b,14-Dihydroxy-5b-card-20(22)-enolide
delta20:22-3,14,21-Trihydroxynorcholenic acid lactone
NSC 407806
DIGITOXIGENIN
5BETA,20[22]-CARDENOLIDE-3BETA,14-DIOL
3BETA,14-DIHYDROXY-5BETA,20[22]-CARDENOLIDE
20(22),5BETA-CARDENOLID-3BETA,14BETA-DIOL
3,14,21-TRIHYDROXY-20(22)-NORCHOLENIC ACID LACTONE
cerberigenin
delta-sup(20:22)-3,14,21-trihydroxynorcholenicacidlactone
digitoxigenine
Digitoxigenin >
igitoxigenin
(+)-digitoxigenin
Card-20(22)-enolide, 3,14-dihydroxy-, (3β,5β)-
143-62-4
Asymmetric Synthesis
Chiral Building Blocks
BioChemical
Steroids
Steroids (Others)
Non-Ionic
Complex Molecules
Detergents
Biochemistry
Steroids
Steroids (Others)
ATPase