3β-Hydroxyurs-12,19-dien-28-oic acid
- CAS No.
- 6812-98-2
- Chemical Name:
- 3β-Hydroxyurs-12,19-dien-28-oic acid
- Synonyms
- Ursa-12;Sanguisorbigenin;3β-Hydroxyurs-12;Tomentosolic acid;19-dien-28-oic acid;19-Dehydroursolic acid;Ursa-12,19-dien-28-oic acid;3β-Hydroxyurs-12,19-dien-28-oic acid;3β-Hydroxyurs-12,19-dien-28-oic acid;Ursa-12,19-dien-28-oic acid, 3-hydroxy-, (3β)-
- CBNumber:
- CB82143356
- Molecular Formula:
- C30H46O3
- Molecular Weight:
- 454.7
- MDL Number:
- MFCD34470924
- MOL File:
- 6812-98-2.mol
- MSDS File:
- SDS
3β-Hydroxyurs-12,19-dien-28-oic acid Chemical Properties,Uses,Production
Biological Activity
Sanguisorbigenin is a natural antibacterial agent that inhibits methicillin-resistant S. aureus (MRSA)[1]. The minimal inhibitory concentration values of Sanguisorbigenin against six strains of S. aureus are in the range of 12.5-50 μg/mL[1]. The expression of blaR1, mecA and blaZ is significantly inhibited in MRSA in a dose-dependent manner when it is treated with sub-MIC (1.56-6.25 μg/mL) concentrations of Sanguisorbigenin. Sanguisorbigenin remarkably reduces the gene expression of mecA. Sanguisorbigenin has a potent antibacterial effect and could effectively reverse the sense of antibiotics by inhibiting the mecA expression and decrease PBP2a expression[1].
References
[1]. S Wang, et al. Antibacterial activity and synergy of antibiotics with sanguisorbigenin isolated from Sanguisorba officinalis L. against methicillin-resistant Staphylococcus aureus. Lett Appl Microbiol. 2021 Mar;72(3):238-244.
3β-Hydroxyurs-12,19-dien-28-oic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3β-Hydroxyurs-12,19-dien-28-oic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3989 | 66 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7892 | 56 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 15185 | 58 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 7059 | 55 |
| Shandong Xiya Chemical Co., Ltd. | 4009903999 13395398332 | sales@xiyashiji.com | China | 20810 | 60 |
| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | 3004654993@qq.com | China | 9175 | 60 |