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2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione

2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Structure
2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione structure
CAS No.
19667-37-9
Chemical Name:
2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione
Synonyms
Rivaroxaban Impurity 120;N-(3-Chloro-2-hydroxypropyl)phthalimide;2-(3-Chloro-2-hydroxypropyl)isoindoline-1,3-dione;2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione;1H-Isoindole-1,3(2H)-dione, 2-(3-chloro-2-hydroxypropyl)-
CBNumber:
CB82356277
Molecular Formula:
C11H10ClNO3
Molecular Weight:
239.65
MDL Number:
MFCD00086198
MOL File:
19667-37-9.mol
Last updated:2023-05-04 15:14:15
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2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Properties

Melting point 95-96.5 °C
Boiling point 405.4±35.0 °C(Predicted)
Density 1.444±0.06 g/cm3(Predicted)
pka 13.25±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H302
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501

2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S413054 N-(3-CHLORO-2-HYDROXYPROPYL)-PHTHALIMIDE AldrichCPR 19667-37-9 50mg $179 2024-03-01 Buy
Product number Packaging Price Buy
S413054 50mg $179 Buy

2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Chemical Properties,Uses,Production

Uses

2-(3-Chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione has been used in yeast biosynthesis of (S)-adrenergic β-blockers by stereoselective reduction of haloketones. It has also been used in a validated LC-?MS?/MS method for the determination of three genotoxic impurities in rivaroxaban drug substance.

2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Preparation Products And Raw materials

Raw materials

Preparation Products

2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione Suppliers

Global( 24)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14336 58
sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12382 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Shanghai ChuangYan Chemical Technology Co., Ltd. 021-11111111 11111111111 546919421@qq.com China 3005 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
shandong XuanHong Pharmaceutical Technology Co.,Ltd 0531-88801869 15562622698 sciencechem@163.com China 275 55
Yantai ShengKailun Chemical Technology Co., Ltd. 13356901049 3119594100@qq.com China 8487 55
Zhengzhou Kangshan Biological Co., Ltd. +86-0371-55023472 +86-13663848272 2584787837@qq.com China 170 58
Guangzhou Dreampharm Biotechnology Co., Ltd. 17825480238 3008233717@qq.com China 9843 12
Block Chemical Technology (Shanghai) Co., LTD 021-20432219 13918097649 li_jinfei@acblock-lab.com China 9562 58
Supplier Advantage
Standardpharm Co. Ltd. 		58
sgtlifesciences pvt ltd 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Shanghai ChuangYan Chemical Technology Co., Ltd. 55
Sigma-Aldrich 80
shandong XuanHong Pharmaceutical Technology Co.,Ltd 55
Yantai ShengKailun Chemical Technology Co., Ltd. 55
Zhengzhou Kangshan Biological Co., Ltd. 58
Guangzhou Dreampharm Biotechnology Co., Ltd. 12
Block Chemical Technology (Shanghai) Co., LTD 58
2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione N-(3-Chloro-2-hydroxypropyl)phthalimide 2-(3-Chloro-2-hydroxypropyl)isoindoline-1,3-dione 1H-Isoindole-1,3(2H)-dione, 2-(3-chloro-2-hydroxypropyl)- Rivaroxaban Impurity 120 19667-37-9 19667-37-2