Bucladesine sodium | 16980-89-5

Bucladesine sodium Properties

Melting point	>173°C (dec.)
storage temp.	-20°C
solubility	H₂O: 50 mg/mL
form	powder
color	white
Merck	14,1463
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
InChIKey	DBXVIQJWMFGXGO-AOTDUVMNNA-N
SMILES	O([C@@H]1[C@]2([H])OP(O)(=O)OC[C@@]2([H])O[C@H]1N1C=NC2C(=NC=NC1=2)NC(=O)CCC)C(=O)CCC.[NaH] \|&1:1,2,10,13,r\|
FDA UNII	4DZN2C97A7

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Safety Statements	24/25
WGK Germany	2
RTECS	ES5055500
F	10-21
HS Code	29349990

Bucladesine sodium price More Price(50)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	28745-M	Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem This Dibutyryl-cAMP, CAS 16980-89-5, is a cell-permeable cAMP analog that preferentially activates PKA.	16980-89-5	25mg	$136	2024-03-01	Buy
Sigma-Aldrich	28745-M	Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶,O2ʹ-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem This Dibutyryl-cAMP, CAS 16980-89-5, is a cell-permeable cAMP analog that preferentially activates PKA.	16980-89-5	100mg	$418	2024-03-01	Buy
Sigma-Aldrich	28745-M	Adenosine 3′,5′-cyclic Monophosphate, N⁶,O^2′-Dibutyryl-, Sodium Salt This Dibutyryl-cAMP, CAS 16980-89-5, is a cell-permeable cAMP analog that preferentially activates PKA.	16980-89-5	1g	$1250	2024-03-01	Buy
Sigma-Aldrich	28745-M	Adenosine 3′,5′-cyclic Monophosphate, N⁶,O2′-Dibutyryl-, Sodium Salt This Dibutyryl-cAMP, CAS 16980-89-5, is a cell-permeable cAMP analog that preferentially activates PKA.	16980-89-5	28745-1GM	$1220	2023-06-20	Buy
TCI Chemical	D4228	N6,2'-O-Dibutyryladenosine 3',5'-Cyclic Monophosphate Sodium Salt >97.0%(HPLC)	16980-89-5	25mg	$121	2024-03-01	Buy

Product number	Packaging	Price	Buy
28745-M	25mg	$136	Buy
28745-M	100mg	$418	Buy
28745-M	1g	$1250	Buy
28745-M	28745-1GM	$1220	Buy
D4228	25mg	$121	Buy

Bucladesine sodium Chemical Properties,Uses,Production

Description

Bucladesine sodium is a derivative of cyclic-AMP with cardiac stimulant and peripheral vasodilatory properties. It is reported to be useful in cardiac insufficiency, especially after heart surgery.

Originator

Daiichi Seiyaku; Seishin Seiyaku (Japan)

Uses

Bucladesine sodium is an analog of cyclic AMP that stimulates cAMP-dependent protein kinase. It has vasodilator properties and is used as a cardiac stimulant.

Definition

ChEBI: Bucladesine sodium is a 3',5'-cyclic purine nucleotide.

Application

N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt has been used:
as a medium supplement for neural crest stem cells (NCSCs) differentiation
as a component of thawing medium for cryopreserved human iPSC (induced pluripotent stem cell)-derived neurons
in serum-free Dulbecco′s modified eagle′s medium (DMEM) to induce astrocyte differentiation

brand name

ACTOCIN

General Description

A cell-permeable cAMP analog that preferentially activates cAMP-dependent protein kinase (PKA). Causes an increase in the steady state level of parathyroid hormone-related peptide mRNA. Also acts as a Hh pathway antagonist. Shown to induce apoptosis in vascular smooth muscle cells.

Biochem/physiol Actions

Cell-permeable cAMP analog that activates cAMP dependent protein kinase (PKA).

storage

Store at -20°C

References

1) Bartsch?et al.?(2003),?Bioactivatable, membrane-permeant analogs of cyclic nucleotides as biological tools for growth control of C6 glioma cells; Biol. Chem.,?384?1321
2) Carranza?et al.?(1998),?Protein kinase A induces recruitment of active Na+,K+-ATPase units to the plasma membrane of rat proximal convoluted tubule cells; J. Physiol.,?15?511
3) Hei?et al.?(1991),?Lack of correlation between activation of cyclic AMP-dependent protein kinase and inhibition of contraction of rat vas deferens by cyclic AMP analogs; Mol. Pharmacol.,?39?233
4) Imamura?et al.?(1998),?Differential expression of dystrophin isoforms and utrophin during dibutyryl-cAMP-induced morphological differentiation of rat brain astrocytes; Proc. Natl. Acad. Sci. USA,?95?6139
5) Xia?et al.?(2016),?Transcriptional comparison of human induced and primary midbrain dopaminergic neurons; Sci. Rep.,?6?20270

Bucladesine sodium Preparation Products And Raw materials

Raw materials

Preparation Products

Bucladesine sodium Suppliers

Global( 320)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
HangZhou RunYan Pharma Technology Co.,LTD.	+86-88660901 +86-18112526015	sales@runyanpharma.com	China	326	58
Hangzhou Meiya Pharmaceutical Co Ltd	+86-021-33686691 +8618001850931	sales@meiyapharm.com	China	57	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Shanxi Naipu Import and Export Co.,Ltd	+86-13734021967 +8613734021967	kaia@neputrading.com	China	1011	58
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	967	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Shanghai Longyu Biotechnology Co., Ltd.	+8615821988213	info@longyupharma.com	China	2531	58

Supplier	Advantage
HangZhou RunYan Pharma Technology Co.,LTD.	58
Hangzhou Meiya Pharmaceutical Co Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Shanxi Naipu Import and Export Co.,Ltd	58
Biochempartner	58
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58
Shanghai Longyu Biotechnology Co., Ltd.	58

View Lastest Price from Bucladesine sodium manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-03-11	Bucladesine sodium salt (DB-cAMP.Na) 16980-89-5	US $0.00-0.00 / kg	1kg	≥95%	5000kg	Hangzhou Meiya Pharmaceutical Co Ltd
2023-11-14	Bucladesine 16980-89-5	US $0.00 / kg	1kg	0.99	20 tons	Hebei Yanxi Chemical Co., Ltd.
2023-09-06	Bucladesine 16980-89-5	US $0.00-0.00 / KG	1KG	99%	500000kg	Hebei Guanlang Biotechnology Co., Ltd.

Bucladesine sodium salt (DB-cAMP.Na)
16980-89-5
US $0.00-0.00 / kg
≥95%
Hangzhou Meiya Pharmaceutical Co Ltd

Bucladesine
16980-89-5
US $0.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

Bucladesine
16980-89-5
US $0.00-0.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

Bucladesine sodium Spectrum

Bucladesine sodium(16980-89-5)¹HNMR Bucladesine sodium(16980-89-5)IR1 Bucladesine sodium(16980-89-5)IR2

16980-89-5(Bucladesine sodium)Related Search:

Adenosine 3',5'-cyclic monophosphate sodium salt NAD+ 8-CHLORO-CAMP 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT MALANTIDE

N-(2-(METHYLAMINO)ETHYL)ISOQUINOLINE- HA-1004 DIHYDROCHLORIDE ARG-ARG-LYS-ALA-SER-GLY-PRO 8-(4-CHLOROPHENYLTHIO)-ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT Bucladesine (calciuM salt)

6-MB-CAMP SODIUM SALT 2'-O-MB-CAMP SODIUM SALT SP-ADENOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE TRIETHYLAMINE 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT PROTEIN KINASE A INHIBITOR 14-22 AMIDE, CELL-PERMEABLE, MYRISTOYLATED

Butyramide Cyclic AMP Bucladesine

1of4

dibutylcyclicampsodium dibutylcyclicampsodiumsalt dt5621sodiumsalt e,butyrate(ester),monosodiumsalt monosodiumdibutyrylcyclicamp n-(9-beta-d-ribofuranosyl-9h-purin-6-yl)-butyramidcyclichydrogenphosphat n6,02’-dibutyryladenosine3’,5’-cyclicmonophosphatesodiumsalt n6,2’-o-dibutyryladenosine-3’,5’-cyclicmonophosphate(dbcamp),sodiumsalt N,2'-O-Dibutanoyladenosine 3',5'-(phosphoric acid sodium) salt N,2'-O-Dibutyryladenosine-3',5'-phosphoric acid sodium salt Sodium bucladesine ,5Õ -cyclophosphate sodium salt monohydrate N6-2Õ -O-Dibutyryl-adenosine 3Õ Adenosine, N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate, monosodium salt Calcium Dibutyacyladenosine Cyclophosphate N6,2'-O-DIBUTYRYLADENOSINE 3':5'-CYCLIC MONOPHOSPHA N6,2'-O-DIBUTYRYLADENOSINE-3',5'-CYCLO-P HOSPHATE SO-SALT Dibutyacyladenosine 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, adenosine deriv. Butyramide, N-(9-b-D-ribofuranosyl-9H-purin-6-yl)-, cyclic hydrogen phosphate butyrate (ester), monosodium salt (8CI) DC 2797 Dibutyryl 3',5'-cyclic AMP sodium salt Dibutyryl cyclic AMP monosodium salt Dibutyryl cyclic AMP sodium N6,2'-O-Dibutyryl-3',5'-cyclic AMP sodium salt N6,2'-O-Dibutyryladenosine-3',5'-monophosphate monosodium salt N6,O2'-Dibutyryl-3',5'-cyclic AMP sodium salt N-6,O-2'-Dibutyryladenosine cyclic 3',5'-monophosphate sodium salt Sodium N6,2'-O-dibutyryladenosine 3',5'-cyclic phosphate DIBUTYRYL-CYCLICAMP BUCLADESINE[N-6,O-2''-DIBUTYRYL ADENOSINE CYCLIC 3'',5''-MONOPHOSPHATE] N6,2'-O-DIBUTRYL-ADENISINE-3',5'-CYCLICMONPHOSPHATE SODIUM SALT Bucladesine sodium salt, Dibutyryl cAMP sodium salt, Dibutyryl cyclic-AMP sodium salt Bucladesine, Dibutyryl cyclic-AMP N6,2μ-O-Dibutyryladenosine 3μ,5μ-cyclic monophosphate monohydrate sodium salt ibutyryl cyclic AMP sodium N6,O2-DIBUTYRYLADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE NA Dibutyacyladenosine cyclphosphate Adenosine,N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate, sodiuM salt(1:1) Adenosine 3?,5?-cyclic Monophosphate, N?,O Dibutyryl-cAMP sodium salt, >=98% adenosine,n-(1-oxobutyl)-,cyclic3’,5’-(hydrogenphosphate)-2’-butanoate,m bucladesinesodium butyramide,n-(9-beta-d-ribofuranosyl-9h-purin-6-yl)-,cyclichydrogenphosphate,butyrate(ester),monosodiumsalt dibutylcampsodiumsalt sodiumdibutyryl3’,5’-cyclicamp sodiumdibutyrylcamp N6, O2-DIBUTYRYLADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE SODIUM SALT N6,O2'-DIBUTYRYL ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT N6,O2'-DIBUTYRYLADENOSINE-3':5'-PHOSPHATE CYCLIC NA-SALT N6,O2'-DIBUTYRYLADENOSINE-3',5'-PHOSPHATE CYCLIC SODIUM SALT N6,2'-O-DIBUTYRYLADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT N6,2'-O-DIBUTYRYLADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT N6,2'-O-DIBUTYRYLADENOSINE-3':5'-CYCLIC MONOPHOSPHORIC ACID, SODIUM ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, N6,O2'-DIBUTYRYL-, SODIUM SALT ADENOSINE-3',5'-CYCLIC MONOPHOSPHORIC ACID, N,2'O-DIBUTYRYL, SODIUM SALT