(1S,7aβ,14aα)-Dodecahydro-7β,14β-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-1-ol
![(1S,7aβ,14aα)-Dodecahydro-7β,14β-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-1-ol Structure](CAS/20180808/GIF/2122-29-4.gif)
- CAS No.
- 2122-29-4
- Chemical Name:
- (1S,7aβ,14aα)-Dodecahydro-7β,14β-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-1-ol
- Synonyms
- Retamine;(1S,7aβ,14aα)-Dodecahydro-7β,14β-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-1-ol;(1S,7aβ,14aα)-Dodecahydro-7β,14β-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-1β-ol;7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-1-ol, dodecahydro-, (1S,7R,7aS,14R,14aS)-
- CBNumber:
- CB82433840
- Molecular Formula:
- C15H26N2O
- Molecular Weight:
- 250.38
- MDL Number:
- MOL File:
- 2122-29-4.mol
| Melting point | 165-166° |
|---|---|
| alpha | D20 +46.2° (c = 1.017 in abs ethanol) |
| EWG's Food Scores | 1 |
| FDA UNII | W1C646VHEF |
(1S,7aβ,14aα)-Dodecahydro-7β,14β-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-1-ol Chemical Properties,Uses,Production
Description
This sparteine alkaloid was first isolated by Battandier and Malosse from Retama sphaerocarpa Boiss. and found to give colour reactions suggesting a relationship with sparteine. It has [α]20D + 46.2° (c 1.017, EtOH) and yields crystalline salts and derivatives including the hydrochloride, m.p. 272-3°C; picrate, m.p. 165- 6°C; phenylurethane, m.p. 190-1 °c and the acetyl derivative as hygroscopic crystals, m.p. about 60°C. The earlier structure as 8-hydroxysparteine has been shown to be wrong, the correct structure, established by synthesis, being 12-{3- hydroxysparteine.
References
Battandier, Malosse., Compt. rend., 125, 360,450 (1897)
Ribas, Sanchez, Primo., Anales, [is. y. quim., 42, 516 (1946)
Ribas, Fraga., Anales. Real. Soc. Espan [is. y. QUim., 45B, 1426 (1949)
Ribas, Fraga., ibid, 46B, 665 (1950)
Fragaetal., Tetrahedron, 11,78 (1960)
Revised structure:
Bohlmann et al., Chem. Ber., 98, 653, 659 (1965)
Ribas, Castedo, Garcfa., Tetrahedron Lett., 3181 (1965)
Shin, Fonzes, Marion., Can. 1. Chem., 43,2012 (1965)
(1S,7aβ,14aα)-Dodecahydro-7β,14β-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-1-ol Preparation Products And Raw materials
Raw materials
Preparation Products
(1S,7aβ,14aα)-Dodecahydro-7β,14β-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-1-ol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9116 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Supplier | Advantage |
|---|---|
| Shaanxi Didu New Materials Co. Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |