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ChemicalBook >> CAS DataBase List >>2,3-dimethyl-6-nitro-2H-indazole

2,3-dimethyl-6-nitro-2H-indazole

2,3-dimethyl-6-nitro-2H-indazole Structure
2,3-dimethyl-6-nitro-2H-indazole structure
CAS No.
444731-73-1
Chemical Name:
2,3-dimethyl-6-nitro-2H-indazole
Synonyms
Pazopanib Impurity 19;3-Methly-6-nitroindazole;2,3-dimethyl-6-nitrobazole;2,3-Dimethyl-6-nitro-1H-i...;2,3-dimethyl-6-nitro-indazole;3-diMethyl-6-nitro-2H-indazole;2,3-dimethyl-6-nitro-1H-indazole;2,3-DIMETHYL-6-NITRO-2H-INDAZOLE;2H-Indazole, 2,3-diMethyl-6-nitro-;2,3-DIMETHYL-6-NITRO-2H-INDAZOLE ISO 9001：2015 REACH
CBNumber:
CB82455022
Molecular Formula:
C9H9N3O2
Molecular Weight:
191.19
MDL Number:
MFCD10703326
MOL File:
444731-73-1.mol
Last updated:2024-03-29 15:13:30
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2,3-dimethyl-6-nitro-2H-indazole Properties

Melting point 183-186°C
Boiling point 377.0±22.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka -0.55±0.30(Predicted)
form Solid
color Yellow

2,3-dimethyl-6-nitro-2H-indazole price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 159866 2,3-Dimethyl-6-nitro-2H-indazole 444731-73-1 500mg $425 2021-12-16 Buy
TRC D471055 2,3-Dimethyl-6-nitro-2H-indazole 444731-73-1 500mg $130 2021-12-16 Buy
American Custom Chemicals Corporation CHM1052130 2,3-DIMETHYL-6-NITRO-2H-INDAZOLE 95.00% 444731-73-1 1G $130.2 2021-12-16 Buy
Biosynth Carbosynth FD148529 2,3-Dimethyl-6-nitro-2H-indazole 444731-73-1 500mg $570 2021-12-16 Buy
Medical Isotopes, Inc. 69723 2,3-Dimethyl-6-nitro-2H-indazole 444731-73-1 500mg $625 2021-12-16 Buy
Product number Packaging Price Buy
159866 500mg $425 Buy
D471055 500mg $130 Buy
CHM1052130 1G $130.2 Buy
FD148529 500mg $570 Buy
69723 500mg $625 Buy

2,3-dimethyl-6-nitro-2H-indazole Chemical Properties,Uses,Production

Uses

2,3-Dimethyl-6-nitro-2H-indazole is an impurity in the synthesis of Pazopanib (P210925) hydrochloride, an oral angiogenesis inhibitor targeting VEGFR and PDGFR.

structure and hydrogen bonding

In the mol-ecule of 2,3-dimethyl-6-nitro-2H-indazole, C9H9N3O2, the indazole ring system is almost planar [maximum deviation = 0.019 (3) Å for the C atom bearing the nitro group]. In the crystal structure, inter-molecular C—H...O inter-actions link the mol-ecules into centrosymmetric dimers, forming R 2 2(18) ring motifs. Aromatic π–π contacts between indazole rings [centroid–centroid distances = 3.632 (1) and 3.705 (1)?] may further stabilize the structure[1].
2,3-DIMETHYL-6-NITRO-2H-INDAZOLE

References

[1] Yan Chen, Ping Wei, Zheng Fang. “2,3-Dimethyl-6-nitro-2H-indazole.” Acta crystallographica. Section E, Structure reports online 65 Pt 8 (2009): o1775.

2,3-dimethyl-6-nitro-2H-indazole synthesis

6494-19-5
616-38-6
444731-73-1
Synthesis of 2,3-dimethyl-6-nitro-2H-indazole from 3-Methyl-6-nitroindazole and Dimethyl carbonate

2,3-dimethyl-6-nitro-2H-indazole Preparation Products And Raw materials

Raw materials

Preparation Products

2,3-dimethyl-2H-indazol-6-amine hydrochloride

2,3-dimethyl-6-nitro-2H-indazole Suppliers

Global( 188)Suppliers
Supplier Tel Email Country ProdList Advantage
Yangzhou Qinyuan Pharmatech Co.,ltd
+86-18752526868 jennysun@yzqyyykj.com China 64 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 7377 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9352 55
Shanghai Yingrui Biopharma Co., Ltd. 		+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
Anqing Chico Pharmaceutical Co., Ltd. 		15380796838 chloewu@chicopharm.cn CHINA 341 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
TianYuan Pharmaceutical CO.,LTD 		+86-755-23284190 13684996853 sales@tianpharm.com CHINA 304 58
Accela ChemBio Inc. 		(+1)-858-699-3322 info@accelachem.com United States 19965 58
Supplier Advantage
Yangzhou Qinyuan Pharmatech Co.,ltd
58
Henan Fengda Chemical Co., Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
Shanghai Yingrui Biopharma Co., Ltd. 		60
Anqing Chico Pharmaceutical Co., Ltd. 		58
career henan chemical co 		58
TianYuan Pharmaceutical CO.,LTD 		58
Accela ChemBio Inc. 		58

View Lastest Price from 2,3-dimethyl-6-nitro-2H-indazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,3-DIMETHYL-6-NITRO-2H-INDAZOLE pictures 2024-03-29 2,3-DIMETHYL-6-NITRO-2H-INDAZOLE
444731-73-1
 US $6.00-0.20 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
2, 3-dimethyl-6-nitroindazole pictures 2023-05-04 2, 3-dimethyl-6-nitroindazole
444731-73-1
 US $48.00-40.00 / KG 1KG 99.99% 20 tons Guangzhou Sunton Biotechnology Co., Ltd.
2,3-dimethyl-6-nitro-1H-indazole pictures 2022-06-21 2,3-dimethyl-6-nitro-1H-indazole
444731-73-1
 US $0.00 / g 10g 98% 10tons Yangzhou Qinyuan Pharmatech Co.,ltd

2,3-dimethyl-6-nitro-2H-indazole Spectrum

2,3-DIMETHYL-6-NITRO-2H-INDAZOLE(444731-73-1)1HNMR

444731-73-1(2,3-dimethyl-6-nitro-2H-indazole )Related Search:

3-Methyl-6-nitroindazole 1,3-DiMethyl-6-aMino-1H-indazole 3-Methyl-6-nitro-2H-indazole Pazopanib Related Compound 3 1,3-Dimethyl-6-nitro-1H-indazole
Pazopanib Related Compound 2 2(1H)-Pyrimidinone, 4-chloro- (6CI,9CI) N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine Pazopanib 2,3-dimethyl-2H-indazol-6-amine hydrochloride
Pazopanib Hydrochloride 2-Ethyl-5-nitrobenzenamine ,98% N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine Pazopanib Impurity 9 Pazopanib Impurity 10
Pazopanib Impurity 2 2-Methyl-5-nitrobenzenesulfonamide 3-AMINO-4-METHYLBENZENESULFONAMIDE

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2,3-DIMETHYL-6-NITRO-2H-INDAZOLE 2,3-dimethyl-6-nitro-1H-indazole 2,3-Dimethyl-6-nitro-1H-i... 2H-Indazole, 2,3-diMethyl-6-nitro- 3-Methly-6-nitroindazole 3-diMethyl-6-nitro-2H-indazole Pazopanib Impurity 19 2,3-dimethyl-6-nitro-indazole 2,3-dimethyl-6-nitrobazole 2,3-DIMETHYL-6-NITRO-2H-INDAZOLE ISO 9001：2015 REACH 444731-73-1