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7-Hydroxygranisetron

CAS No.
4498-67-3
Chemical Name:
7-Hydroxygranisetron
Synonyms
INDAPAMIDE;1H-INDAZOLE-3-CARBOXYLIC ACID;INDAZOLE-3-CARBOXYLIC ACID;1H-INDAZOL-3-CARBONIC ACID;NSC 520610;AKOS BB-9978;3-CARBOXYINDAZOLE;Indazole - 3 - carbo;3-Carboxy-1H-indazole;Indazole-3-carboxylicaci
CBNumber:
CB8247050
Molecular Formula:
C8H6N2O2
Molecular Weight:
162.15
MDL Number:
MFCD00211066
MOL File:
4498-67-3.mol
MSDS File:
SDS
Last updated:2024-03-26 17:16:27

7-Hydroxygranisetron Properties

Melting point 266-270 °C (dec.)
Boiling point 443.7±18.0 °C(Predicted)
Density 1.506±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form powder
pka 3.03±0.10(Predicted)
color beige
BRN 6354
InChI InChI=1S/C8H6N2O2/c11-8(12)7-5-3-1-2-4-6(5)9-10-7/h1-4H,(H,9,10)(H,11,12)
InChIKey BHXVYTQDWMQVBI-UHFFFAOYSA-N
SMILES N1C2=C(C=CC=C2)C(C(O)=O)=N1
CAS DataBase Reference 4498-67-3(CAS DataBase Reference)
FDA UNII Z1YOL9C0VN

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P264-P270-P280-P301+P312-P305+P351+P338-P337+P313
Hazard Codes  Xn,Xi
Risk Statements  22-36-36/37/38
Safety Statements  26-36/37/39-22
WGK Germany  3
HazardClass  IRRITANT
HS Code  29339900
NFPA 704
1
2 0

7-Hydroxygranisetron price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 56915 Indazole-3-carboxylic acid ≥97.0% (HPLC) 4498-67-3 10g $138 2023-06-20 Buy
Sigma-Aldrich 56915 Indazole-3-carboxylic acid ≥97.0% (HPLC) 4498-67-3 50g $468 2023-06-20 Buy
TCI Chemical I0672 Indazole-3-carboxylic Acid >98.0%(HPLC)(T) 4498-67-3 5g $21 2024-03-01 Buy
TCI Chemical I0672 Indazole-3-carboxylic Acid >98.0%(HPLC)(T) 4498-67-3 25g $57 2024-03-01 Buy
Alfa Aesar H64001 1H-Indazole-3-carboxylic acid, 98% 4498-67-3 5g $29.65 2024-03-01 Buy
Product number Packaging Price Buy
56915 10g $138 Buy
56915 50g $468 Buy
I0672 5g $21 Buy
I0672 25g $57 Buy
H64001 5g $29.65 Buy

7-Hydroxygranisetron Chemical Properties,Uses,Production

Chemical Properties

yellow crystal

Uses

Indazole-3-carboxylic acid may be used in the synthesis of the following:

  • N-(8-methyl-azabicyclo[3.2.11]oct-3-yl)-1H-indazole-3-carboxamide
  • N-(1- benzyl-4-methylhexahydro-1H-1,4-diazepin-6-yl)-1H-indazole-3-carboxamide
  • 1H-indazole-3-carboxamide

Uses

Indazole-3-carboxylic acid is indole derivatives useful in treatment of pain and inflammation

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 26, p. 531, 1989 DOI: 10.1002/jhet.5570260251

186966-06-3
4498-67-3
Synthesis of 7-Hydroxygranisetron from 1H-Indazole-3-carboxylic acid, 1-acetyl-, methyl ester
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View Lastest Price from 7-Hydroxygranisetron manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
7-Hydroxygranisetron pictures 2024-04-19 7-Hydroxygranisetron
4498-67-3
US $1.00 / ASSAYS 1ASSAYS 99% 1000kg Dorne Chemical Technology co. LTD
7-Hydroxygranisetron pictures 2024-04-19 7-Hydroxygranisetron
4498-67-3
US $280.00 / kilograms 10kilograms 99% 100tons Hebei Dangtong Import and export Co LTD
1H-indazole-3-carboxylic acid pictures 2024-04-12 1H-indazole-3-carboxylic acid
4498-67-3
US $0.00 / kg 1kg 0.99 10T Shandong Hanjiang Chemical Co., Ltd
1H-INDAZOLE-3-CARBONIC ACID AKOS BB-9978 3-INDAZOLECARBOXYLIC ACID 3-CARBOXYINDAZOLE ndazole-3-carboxylic acid 3-Carboxy-1H-indazole 3(1H)-Indazolecarboxylic Acid NSC 520610 Indazole-3-carboxylic acid ,98% Indazole-3-carboxylic acid,97% 1H-Indazole-3-carboxylic ... Indazole-3-carboxylic acid 1H-Indazole-3-carboxylic acid Indazole-3-carboxylic acid >=97.0% (HPLC) Benzopyrazole-3-carboxylic acid Granisetron Impurity 8(Granisetron EP Impurity H) Granisetron EP impurity H Indazole-3-carboxylicAcid> 7-Hydroxygranisetron ISO 9001:2015 REACH Indazole - 3 - carbo 1H-INDAZOL-3-CARBONIC ACID 1H-INDAZOLE-3-CARBOXYLIC ACID INDAZOLE-3-CARBOXYLIC ACID INDAPAMIDE Indazole-3-carboxylicaci Content of indazole -3- carboxylic acid Indazole-3-carboxylic acid (7CI) Granisetron Hydrochloride EP Impurity H Granisetron Hydrochloride Impurity H 4498-67-3 581083-36-9 498-67-3 C8H6N2O2 Heterocyclic Building Blocks Indazoles Building Blocks Indoles and derivatives pharmacetical Carboxylic Acids Organic acids Acids and Derivatives Heterocycles (intermediate of granisetron) Indazoles Indole Derivatives Carboxylic Acids Fused Ring Systems Building Blocks Heterocyclic Building Blocks PHARMACEUTICAL INTERMEDIATES