ChemicalBook >> CAS DataBase List >>p-Toluenesulfonyl Isocyanate
p-Toluenesulfonyl Isocyanate
- CAS No.
- 4083-64-1
- Chemical Name:
- p-Toluenesulfonyl Isocyanate
- Synonyms
- PTSI;p-Tosyl isocyanate;P-TOLUENESULPHONYL ISOCYANATE;TOSYL ISOCYANATE;Ptsl;MSI/PTSI;POLYLINK PTSI;PARA-TOSYLISOCYANATE;TOSYL ISOCYANATE (PTSI);Sulfone, isocyanato tolyl
- CBNumber:
- CB8256995
- Molecular Formula:
- C8H7NO3S
- Molecular Weight:
- 197.21
- MDL Number:
- MFCD00002030
- MOL File:
- 4083-64-1.mol
- MSDS File:
- SDS
Last updated:2024-04-08 17:36:13
| Melting point | 5°C |
|---|---|
| Boiling point | 144 °C10 mm Hg(lit.) |
| Density | 1.291 g/mL at 25 °C(lit.) |
| vapor pressure | 1 mm Hg ( 100 °C) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | Liquid |
| Specific Gravity | 1.291.291 |
| color | Clear colorless to yellow |
| Odor | acrid odor |
| Water Solubility | reacts |
| Sensitive | Moisture Sensitive |
| BRN | 391287 |
| InChIKey | VLJQDHDVZJXNQL-UHFFFAOYSA-N |
| LogP | 0.6 at 30℃ |
| CAS DataBase Reference | 4083-64-1(CAS DataBase Reference) |
| FDA UNII | H9004FJX6V |
| NIST Chemistry Reference | 4-Methylbenzenesulfonyl isocyanate(4083-64-1) |
| EPA Substance Registry System | Benzenesulfonyl isocyanate, 4-methyl- (4083-64-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H319-H334-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 14-36/37/38-42 | |||||||||
| Safety Statements | 26-28-30-28A | |||||||||
| RIDADR | UN 2206 6.1/PG 3 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | DB9032000 | |||||||||
| F | 10 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29309090 | |||||||||
| NFPA 704 |
|
p-Toluenesulfonyl Isocyanate price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 189278 | p-Toluenesulfonyl isocyanate 97% | 4083-64-1 | 25g | $43.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | 189278 | p-Toluenesulfonyl isocyanate 97% | 4083-64-1 | 100g | $45.3 | 2024-03-01 | Buy |
| TCI Chemical | T0998 | p-Toluenesulfonyl Isocyanate >97.0%(T) | 4083-64-1 | 25g | $18 | 2024-03-01 | Buy |
| TCI Chemical | T0998 | p-Toluenesulfonyl Isocyanate >97.0%(T) | 4083-64-1 | 100g | $31 | 2024-03-01 | Buy |
| Alfa Aesar | A17492 | p-Toluenesulfonyl isocyanate, 95% | 4083-64-1 | 25g | $20.65 | 2024-03-01 | Buy |
p-Toluenesulfonyl Isocyanate Chemical Properties,Uses,Production
Chemical Properties
clear liquid
Uses
It is a reagent used to prepare acetylated syn-1,2-diols,oxazolidin-2-ones, 2,3-diamino acids, and N-tosylcarbonamides. -Toluenesulfonyl isocyanate has been used as derivatization reagent in determination of 3-α-hydroxy tibolone in human plasma by LC-MS/MS. It is also employed in the derivatization reagent in simultaneous quantitative analysis of diethylene glycol and propylene glycol in pharmaceutical products by HPLC and as reagent in the preparation of acetylated syn-1,2-diols, oxazolidin-2-ones, 2,3-diamino acids and N-tosylcarbonamides.
Uses
p-Toluenesulfonyl isocyanate is a reagent used to prepare acetylated syn-1,2-diols,1 oxazolidin-2-ones,2 2,3-diamino acids,3 and N-tosylcarbonamides.4
Synthesis Reference(s)
Tetrahedron Letters, 35, p. 9609, 1994 DOI: 10.1016/0040-4039(94)88523-0
General Description
p-Toluenesulfonyl isocyanate undergoes palladium-catalyzed bis-allylation reaction with allylstannanes and allyl chlorides.
Hazard
Moderately toxic by ingestion. Low toxicity by inhalation. A mild skin and moderate eye irritant.
Synthesis
Add the organic azide (0.75 mmol), Pd(OAc)2
(5.6 mg, 5 mol%) to an oven-dried Schlenk tube (10 mL). Purge the tube
and backfill with CO (three cycles) from a balloon. Inject anhydrous
MeCN (3.0 mL) into the tube. Stir at 80??C for 4 h under CO atmosphere
(balloon). Concentrate the mixture under reduced pressure. Purify the
residue by column chromatography (petroleum ether/EtOAc 3:1.-.1:1).
p-Toluenesulfonyl Isocyanate Preparation Products And Raw materials
Global( 415)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
| Tianjin Zhongxin Chemtech Co., Ltd. | +86-022-66880623 +8618622897568 | sales@tjzxchem.com | China | 559 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7934 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales02@airuikechemical.com | China | 994 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1807 | 55 |
Related articles
- Synthesis and Application of p-Toluenesulfonyl Isocyanate
- p-Toluenesulfonyl isocyanate is a synthetic material intermediate.
- Sep 2，2022
View Lastest Price from p-Toluenesulfonyl Isocyanate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-26 | p-Toluenesulfonyl isocyanate
4083-64-1
|
US $2.00 / kg | 1kg | 99% | 500mt | Jinan Finer Chemical Co., Ltd | |
 |
2024-04-12 | p-Toluenesulfonyl Isocyanate
4083-64-1
|
US $0.00 / kg | 1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd | |
 |
2024-04-08 | Tosyl isocyanate
4083-64-1
|
US $0.00-0.00 / Kg | 1Kg | 99.9% | 200tons | airuikechemical co., ltd. |
-
- p-Toluenesulfonyl isocyanate
4083-64-1
- US $2.00 / kg
- 99%
- Jinan Finer Chemical Co., Ltd
-
- p-Toluenesulfonyl Isocyanate
4083-64-1
- US $0.00 / kg
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd
-
- Tosyl isocyanate
4083-64-1
- US $0.00-0.00 / Kg
- 99.9%
- airuikechemical co., ltd.
4083-64-1(p-Toluenesulfonyl Isocyanate)Related Search:
4-Isocyanatosulphonyltoluene,
p-Toluenesulfonyl isocyanate, 96%, AcroSeal
Isocyanicacid, anhydride with p-toluenesulfonic acid (6CI)
p-Toluenesulfonyl isocyanate 96%
p-Toluenesulfonyl isocyanate, 96%, SpcSeal
p-Toluenesulfonylisocyanate,95%
Benzenesulfonyl isocyanate, 4-methyl-
Benzenesulfonylisocyanate,4-methyl-
p-Methylphenylsulfonyl isocyanate
p-Toluenesulfonic acid, anhydride with isocyanic acid
p-Toluensulfonyl isocyanate
p-Tolylsulfonyl isocyanate
Sulfone, isocyanato tolyl
P-TOLUENESULFONYL ISOCYANATE
TOLUENE-4-SULFONYL ISOCYANATE
4-METHYLBENZENE-1-SULFONYL ISOCYANATE
4-TOLUENESULFONYL ISOCYANATE
4-methyl-benzenesulfonylisocyanat
4-methyl-Benzenesulfonylisocyanate
4-Methylphenylsulfonyl isocyanate
PARA-TOSYLISOCYANATE
p-Toluolsulfonylisocyanat
P-toluenesulfonyl isocyanate (Tosyl isocyanate ,PTSI)
p-Toluenesulfonyl Isocyanate, PTSI, Tosyl Isocyanate
4-isocyanatosulphonyltoluene tosyl isocyanate
p-Toluenesulfonyl isocyanate,96%
p-Toluenesulfonyl isocyanate, AcroSeal, 96%
P-toluenesulfony6l isocyanate
4-methylbenzene-1-sulphonyl isocyanate
Para Toluene Sulfonyl Isocyanate
POLYLINK PTSI
P-TOULENESULFONYL ISOCYANATE(TOULENESULFONYL ISOCYANATE)
P-TOLUENESULFONYL ISOCYANATE(PTSI)98%
4-METHYLBENZENESULPHONYLISOCYANATE
TOSYL ISOCYANATE (PTSI)
P**P-TOLUENESULFONYL ISOCYANATE
Ptsl
4-Methyl-N-(oxomethylene)benzenesulfonamide
MSI/PTSI
p-Toluenesulfonyl isocyanate, 96%, AcroSeal&trade
4-methyl-N-(oxomethylidene)benzenesulfonamide
p-Tosyl isocyanate
P-TOLUENESULPHONYL ISOCYANATE
PTSI
TOSYL ISOCYANATE
4083-64-1
CH3C6H4SO2NCO
ISOCYANATE
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