ChemicalBook >> CAS DataBase List >>Amorolfine hydrochloride
Amorolfine hydrochloride
- CAS No.
- 78613-38-4
- Chemical Name:
- Amorolfine hydrochloride
- Synonyms
- Odenil;Locetar;Curanail;Amorolfine HCI;AMOROLFINE HCL;Ro 14-4767/002;Amorolfine hydrochloride;Amorolfine Hydrochloride >Amorolfine hydrochloride CRS;13C6]-Amorolfine hydrochloride
- CBNumber:
- CB8262394
- Molecular Formula:
- C21H36ClNO
- Molecular Weight:
- 353.98
- MDL Number:
- MFCD00903738
- MOL File:
- 78613-38-4.mol
Last updated:2023-10-09 22:51:44
| Boiling point | 120 C |
|---|---|
| storage temp. | room temp |
| solubility | DMSO: ≥5mg/mL (warmed) |
| form | powder |
| color | white to beige |
| InChIKey | XZKWIPVTHGWDCF-KUZYQSSXSA-N |
| CAS DataBase Reference | 78613-38-4(CAS DataBase Reference) |
| FDA UNII | 741YH7379H |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H411 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| Hazard Codes | Xn,N | |||||||||
| Risk Statements | 20/21/22-36/37/38-50/53-38-22 | |||||||||
| Safety Statements | 26-36-61 | |||||||||
| RIDADR | UN 3077 9 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29411010 | |||||||||
| NFPA 704 |
|
Amorolfine hydrochloride price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0283 | Amorolfine hydrochloride ≥98% (HPLC) | 78613-38-4 | 10mg | $140 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0283 | Amorolfine hydrochloride ≥98% (HPLC) | 78613-38-4 | 50mg | $429 | 2024-03-01 | Buy |
| TCI Chemical | A2161 | Amorolfine Hydrochloride >98.0%(T) | 78613-38-4 | 1g | $238 | 2024-03-01 | Buy |
| TCI Chemical | A2161 | Amorolfine Hydrochloride >98.0%(T) | 78613-38-4 | 200mg | $79 | 2024-03-01 | Buy |
| Cayman Chemical | 26077 | Amorolfine (hydrochloride) ≥98% | 78613-38-4 | 100mg | $62 | 2024-03-01 | Buy |
Amorolfine hydrochloride Chemical Properties,Uses,Production
Description
Amorolfine hydrochloride is the first morpholine antifungal agent useful in the topical treatment of onychomycosis. Mechanistically, it appears to inhibit two stages of the ergosterol biosynthetic pathway, which is necessary for fungal cell viability. Active against a broad spectrum of fungi, amorolfiie hydrochloride is particularly effective against yeasts such as Histoplasma capsulatum, dermatophytes and dematiaceous fungi.
Chemical Properties
Liquid
Originator
Roche (Switzerland)
Uses
Amorolfine hydrochloride has been used as an antifungal agent.
Uses
antihypertensive
Definition
ChEBI: A hydrochloride resulting from the formal reacton of equimolar amounts of hydrogen chloride and amorolfine. An inhibitor of the action of squalene monooxygenase, Delta14 reductase and D7-D8 isomerase and an antifungal ag nt, it is used for the topical treatment of fungal nail and skin infections.
brand name
Loceryl (Hoffmann-LaRoche).
Biochem/physiol Actions
Amorolfine is a broad-based antifungal agent with fungicidal effects against most fungi, dermatophytes and yeasts. Amorolfine blocks ergosterol biosynthesis by interfering with delta 14 reduction and the delta 7-8 isomerisation.
Amorolfine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 344)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12457 | 58 |
| Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 436 | 58 |
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1100 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
View Lastest Price from Amorolfine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-15 | Amorolfine hydrochloride
78613-38-4
|
US $1.00 / mg | 1mg | 0.99 | 5ton/month | ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD | |
 |
2023-10-09 | Amorolfine hydrochloride
78613-38-4
|
US $30.00 / KG | 1KG | 99% | 20T | Firsky International Trade (Wuhan) Co., Ltd | |
 |
2023-09-04 | Amorolfine hydrochloride
78613-38-4
|
US $0.00-0.00 / kg | 1kg | 99.9% | 20tons | Hebei Xinsheng New Material Technology Co., LTD. |
-
- Amorolfine hydrochloride
78613-38-4
- US $1.00 / mg
- 0.99
- ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
-
- Amorolfine hydrochloride
78613-38-4
- US $30.00 / KG
- 99%
- Firsky International Trade (Wuhan) Co., Ltd
-
- Amorolfine hydrochloride
78613-38-4
- US $0.00-0.00 / kg
- 99.9%
- Hebei Xinsheng New Material Technology Co., LTD.
78613-38-4(Amorolfine hydrochloride)Related Search:
Moroxydine hydrochloride
Moroxydine
Amorolfine hydrochloride
1-AdaMantanethylaMine
ISOPROPYLHYDRAZINE HYDROCHLORIDE
1of4
AMOROLFINE HCL
Amorolfine HCI
Morpholine, 4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-, hydrochloride, (2R,6S)-rel-
Morpholine, 4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-, hydrochloride, cis-
Ro 14-4767/002
(+/-)-cis-2,6-Dimethyl-4-[2-methyl-3-(p-tert-pentylphenyl)propyl]morpholine hydrochloride
Amorolfine hydrochloride
(2R,6S)-rel-4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine, hydrochloride (1:1)
(2R,6S)-rel-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine hydrochloride
Amorolfine hydrochloride, >=99%
Amorolfine for system suitability
(2R,6S)-2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride
AMOROLFIN; CURANAIL; LOCERYL; LOCETAR; ODENIL
Curanail
Locetar
Odenil
2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine hydrochloride
Amorolfine Hydrochloride >
Amorolfine for system suitability CRS
Amorolfine hydrochloride CRS
cis-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine hydrochloride
2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine
(2R,6S)-rel-2,6-Dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride
Amorolfine hydrochloride USP/EP/BP
Amorolfine HCl (Ro 14-4767/002)
Amorolfine HydrochlorideQ: What is
Amorolfine Hydrochloride Q: What is the CAS Number of
Amorolfine Hydrochloride Q: What is the storage condition of
Amorolfine Hydrochloride Q: What are the applications of
Amorolfine Hydrochloride
13C6]-Amorolfine hydrochloride
rel-(2R,6S)-2,6-Dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride (Amorolfine Impurity)
(2S,6R)-2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride
78613-38-4
78163-38-4
C21H35ONHCl
HYTRIN
Antifungal (Topical)
Antifungals for Research and Experimental Use
Biochemistry
78613-38-4