ChemicalBook >> CAS DataBase List >>L-778123
L-778123
- CAS No.
- 183499-57-2
- Chemical Name:
- L-778123
- Synonyms
- 123;L-778;L 778;L-778123 free base;L 778123 free base,L778123 free base;1-(3-chlorophenyl)-4-[1-(4-cyanobenzyl)-5-imidazolylmethyl]-2-piperazinone;L-778123 FREE BASE; L-778123; L 778123; L778123; L-778,123; L 778,123; L778,123;;4-[5-[4-(3-Chlorophenyl)-3-oxopiperazin-1-ylmethyl]imidazol-1-ylmethyl]benzonitrile;4-[[5-[[4-(3-chlorophenyl)-3-oxo-1-piperazinyl]methyl]-1H-imidazol-1-yl]methyl]Benzonitrile;4-((5-((4-(3-Chlorophenyl)-3-oxopiperazin-1-yl)methyl)-1H-imidazol-1-yl)methyl)benzonitrile
- CBNumber:
- CB82628017
- Molecular Formula:
- C22H20ClN5O
- Molecular Weight:
- 405.88
- MDL Number:
- MFCD00951568
- MOL File:
- 183499-57-2.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:18
Boiling point | 698.9±55.0 °C(Predicted) |
---|---|
Density | 1.29±0.1 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
solubility | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:9): 0.1 mg/ml,Ethanol: 10 mg/ml |
form | A crystalline solid |
pka | 7.07±0.20(Predicted) |
FDA UNII | 31ZXM8ZKQ3 |
L-778123 price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Alichem | 183499572 | 4-((5-((4-(3-Chlorophenyl)-3-oxopiperazin-1-yl)methyl)-1H-imidazol-1-yl)methyl)benzonitrile | 183499-57-2 | 100mg | $420.82 | 2021-12-16 | Buy |
Alichem | 183499572 | 4-((5-((4-(3-Chlorophenyl)-3-oxopiperazin-1-yl)methyl)-1H-imidazol-1-yl)methyl)benzonitrile | 183499-57-2 | 250mg | $623.28 | 2021-12-16 | Buy |
Chemenu | CM250631 | 4-((5-((4-(3-Chlorophenyl)-3-oxopiperazin-1-yl)methyl)-1H-imidazol-1-yl)methyl)benzonitrile 97% | 183499-57-2 | 1g | $1485 | 2021-12-16 | Buy |
Alichem | 183499572 | 4-((5-((4-(3-Chlorophenyl)-3-oxopiperazin-1-yl)methyl)-1H-imidazol-1-yl)methyl)benzonitrile | 183499-57-2 | 1g | $1683.28 | 2021-12-16 | Buy |
L-778123 Chemical Properties,Uses,Production
Definition
ChEBI: L-778,123 (free base) is a member of the class of imidazoles that is 1H-imidazole substituted by (4-cyanophenyl)methyl and [4-(3-chlorophenyl)-3-oxopiperazin-1-yl]methyl groups at positions 1 and 5, respectively. It is a dual inhibitor of FPTase and GGPTase-I. It has a role as an EC 2.5.1.58 (protein farnesyltransferase) inhibitor, an EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitor and an antineoplastic agent. It is a member of monochlorobenzenes, a piperazinone, a member of imidazoles, a tertiary amino compound and a nitrile.
L-778123 Preparation Products And Raw materials
Raw materials
Preparation Products
L-778123 Suppliers
Global( 22)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52861 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 17702719238 | sales@sun-shinechem.com | China | 918 | 64 |
SPIRO PHARMA | eric_feng1954@126.com | China | 9254 | 55 | |
ShangHai Siyan Biological Technology Co., Ltd. | 021-50908862,442785678,326799392 18721037013 | siyansales@126.com | China | 9638 | 58 |
ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8015 | 62 |
Shanghai Kangman Biological Technology Co., Ltd. | 18800375331 | kangmansales@163.com | China | 7580 | 55 |
Wuhan Sun-shine Bio-technology Corporation Limited | +86-027-6552-2453 | sales@sun-shinechem.com | China | 727 | 58 |
4-[[5-[[4-(3-chlorophenyl)-3-oxo-1-piperazinyl]methyl]-1H-imidazol-1-yl]methyl]Benzonitrile
Benzonitrile, 4-[[5-[[4-(3-chlorophenyl)-3-oxo-1-piperazinyl]methyl]-1H-imidazol-1-yl]methyl]-
4-[5-[4-(3-Chlorophenyl)-3-oxopiperazin-1-ylmethyl]imidazol-1-ylmethyl]benzonitrile
4-((5-((4-(3-Chlorophenyl)-3-oxopiperazin-1-yl)methyl)-1H-imidazol-1-yl)methyl)benzonitrile
123
L 778
L-778
L-778123 free base
L-778123 FREE BASE; L-778123; L 778123; L778123; L-778,123; L 778,123; L778,123;
1-(3-chlorophenyl)-4-[1-(4-cyanobenzyl)-5-imidazolylmethyl]-2-piperazinone
L 778123 free base,L778123 free base
183499-57-2