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Doramectin aglycone

CAS No.
1987883-26-0
Chemical Name:
Doramectin aglycone
Synonyms
Doramectin aglycone;25R-cyclohexyl-22,23-didehydro-5-O-demethyl-28-deoxy-6R,28-epoxy-13S-hydroxy-milbemycinB;Milbemycin B, 25-cyclohexyl-22,23-didehydro-5-O-demethyl-28-deoxy-6,28-epoxy-13-hydroxy-, (6R,13S,25R)-
CBNumber:
CB82744539
Molecular Formula:
C36H50O8
Molecular Weight:
610.7774
MDL Number:
MFCD33021547
MOL File:
1987883-26-0.mol
Last updated:2023-05-21 10:59:17

Doramectin aglycone Properties

Boiling point 809.2±65.0 °C(Predicted)
Density 1.25±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form A solid
pka 12.43±0.70(Predicted)

Doramectin aglycone price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 23655 Doramectin aglycone ≥95% 1987883-26-0 1mg $332 2024-03-01 Buy
Cayman Chemical 23655 Doramectin aglycone ≥95% 1987883-26-0 5mg $1157 2023-06-20 Buy
AK Scientific 1472EN (1'R,2R,3S,4'S,6S,8'R,10'Z,12'S,13'S,14'Z,20'R,21'R,24'S)-2-Cyclohexyl-12',21',24'-trihydroxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one 1987883-26-0 5mg $1412 2021-12-16 Buy
AK Scientific 1472EN (1'R,2R,3S,4'S,6S,8'R,10'Z,12'S,13'S,14'Z,20'R,21'R,24'S)-2-Cyclohexyl-12',21',24'-trihydroxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one 1987883-26-0 1mg $503 2021-12-16 Buy
Product number Packaging Price Buy
23655 1mg $332 Buy
23655 5mg $1157 Buy
1472EN 5mg $1412 Buy
1472EN 1mg $503 Buy

Doramectin aglycone Chemical Properties,Uses,Production

Description

Doramectin aglycone is an acid degradation product of doramectin , a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes, and its acid-catalyzed hydrolysis product doramectin monosaccharide . Doramectin undergoes one round of acid-catalyzed hydrolysis to form doramectin monosaccharide which is then hydrolyzed again to remove the remaining saccharide unit and form doramectin aglycone.

Uses

Doramectin aglycone is an acid degradation product produced by hydrolysis of the disaccharide unit of doramectin. Doramectin aglycone is an inhibitor of nematode larval development, but is devoid of paralytic activity. Despite the importance of doramectin as an anthelmintic in animal health, there are no published reports of the biological activity or the levels of doramectin aglycone in animals or in the environment.

Doramectin aglycone Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC Sciences
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Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 12007 58
Doramectin aglycone Milbemycin B, 25-cyclohexyl-22,23-didehydro-5-O-demethyl-28-deoxy-6,28-epoxy-13-hydroxy-, (6R,13S,25R)- 25R-cyclohexyl-22,23-didehydro-5-O-demethyl-28-deoxy-6R,28-epoxy-13S-hydroxy-milbemycinB 1987883-26-0