ChemicalBook >> CAS DataBase List >>Triphenylphosphine oxide

Triphenylphosphine oxide

CAS No.
791-28-6
Chemical Name:
Triphenylphosphine oxide
Synonyms
TPO;TPPO;Ph3PO;TTPO;Triphenylphosphinoxid;triphenylphosphane oxide;Trisphenylphosphine oxide;Triphenyl phosphorus oxide;Orlistat Related CoMpound C;PP 560
CBNumber:
CB8296821
Molecular Formula:
C18H15OP
Molecular Weight:
278.28
MDL Number:
MFCD00002080
MOL File:
791-28-6.mol
MSDS File:
SDS
Last updated:2023-10-23 17:13:05

Triphenylphosphine oxide Properties

Melting point 150-157 °C(lit.)
Boiling point 360 °C
Density 1,212 g/cm3
vapor pressure <1 hPa (50 °C)
Flash point 180 °C
storage temp. Store below +30°C.
solubility methanol: 25 mg/mL, clear
form Crystalline Powder or Flakes
Specific Gravity 1.212
color White to pink-brown
Water Solubility slightly soluble
Hydrolytic Sensitivity 4: no reaction with water under neutral conditions
BRN 745854
LogP 2.8
CAS DataBase Reference 791-28-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII Z69161FKI3
NIST Chemistry Reference (C6H5)3PO(791-28-6)
EPA Substance Registry System Triphenylphosphine oxide (791-28-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Warning
Hazard statements  H290
Precautionary statements  P234-P390
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-52/53
Safety Statements  26-61-36
RIDADR  3077
WGK Germany  2
RTECS  SZ1676000
Autoignition Temperature 590 °C
TSCA  Yes
HazardClass  9
PackingGroup  III
HS Code  29310095
Toxicity LD50 orally in Rabbit: 685 mg/kg
NFPA 704
0
2 0

Triphenylphosphine oxide price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2544 Orlistat Related Compound C Pharmaceutical Secondary Standard; Certified Reference Material 791-28-6 50MG $602 2024-03-01 Buy
Sigma-Aldrich 1478833 Orlistat Related Compound C United States Pharmacopeia (USP) Reference Standard 791-28-6 25mg $1490 2024-03-01 Buy
Sigma-Aldrich 08902 Triphenylphosphine oxide analytical standard 791-28-6 100mg $151 2024-03-01 Buy
TCI Chemical T0625 Triphenylphosphine Oxide >98.0%(GC) 791-28-6 25g $27 2024-03-01 Buy
TCI Chemical T0625 Triphenylphosphine Oxide >98.0%(GC) 791-28-6 100g $58 2024-03-01 Buy
Product number Packaging Price Buy
PHR2544 50MG $602 Buy
1478833 25mg $1490 Buy
08902 100mg $151 Buy
T0625 25g $27 Buy
T0625 100g $58 Buy

Triphenylphosphine oxide Chemical Properties,Uses,Production

Description

Triphenylphosphine oxide (TPPO) is a coordinating solvent used to activate crystallization of chemical compounds. It has been used in flame retardant applications, as an epoxy cure catalyst, and more recently, to produce nanostructures.

Chemical Properties

White solid

Uses

Triphenylphosphine oxide can be used:
As a catalyst in Appel-type chlorination reaction of acyclic primary and secondary alcohols.
As a catalyst in stereoselective poly and dibromination of α,β-unsaturated esters and β,γ-unsaturated α-ketoester compounds.
As a promotor in the diastereoselective synthesis of α-ribofuranosides through ribofuranosylation of alcohols with ribofuranosyl iodides.

Uses

Triphenylphosphine Oxide (Orlistat USP Related Compound C) is a catalyst in the conversion of aldehydes into 1,1-dichlorides. Triphenylphosphine Oxide is used as a catalyst for the synthesis of hightly functionalized α-CF3 γ-keto esters.

Uses

Triphenylphosphine oxide is a phosphine ligand used for coupling reactions, epoxidations, and Michael reactions

Definition

ChEBI: A phosphine oxide in which the substituents on phosphorus are three phenyl groups.

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 5463, 1990 DOI: 10.1016/S0040-4039(00)97873-0

Flammability and Explosibility

Not classified

Purification Methods

It crystallises from absolute EtOH and is dried in vacuo. The gold chloride complex has m 177.5-178.5o. [Addison & Sheldon J Chem Soc 2705 1956, Cox & Westheimer J Am Chem Soc 80 5441 1958, Beilstein 16 III 864, 16 1011.]

Global( 555)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12452 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5988 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2504 58
Henan Fengda Chemical Co., Ltd
+8613613820652 info@fdachem.com China 5085 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 14764 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9354 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2989 55

Related articles

View Lastest Price from Triphenylphosphine oxide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Triphenylphosphine oxide pictures 2024-01-14 Triphenylphosphine oxide
791-28-6
US $5.00-0.50 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
Triphenylphosphine oxide pictures 2023-11-13 Triphenylphosphine oxide
791-28-6
US $153.40 / Kg/Bag 25KG 99% 300tons Wuhan Boye Science And Technology Development Co., Ltd.
Triphenylphosphine oxide pictures 2023-10-23 Triphenylphosphine oxide
791-28-6
US $50.00 / kg 1kg 0.99 10000 Hebei Yanxi Chemical Co., Ltd.
(C6H5)3P=O Orlistat USP RC C Orlistat Related Compound C (25 mg) (Triphenylphosphine oxide) Triphenylphosphine oxide(TPPO) Triphenylphosphine oxide, 99% 100GR Orlistat USP Related Compound C (Triphenylphosphine Oxide) Mouse Thrombopoietin ELISA Kit Human Thrombopoietin ELISA Kit Triphenylphosphine oxide≥ 99.5% (Assay) Phosphine oxide, triphenyl- Triphenylphosphanoxid Triphenylphosphanoxide triphenyl-phosphineoxid triphenylphosphorusoxide AURORA KA-1603 oxo(triphenyl)phosphorane Di(phenyl)phosphorylbenzene Triphenylphosphine monoxide TRIPHENYLPHOSPHINE OXIDE TriphenylphosphineOxide,>98% Triphenylphosphineoxide,99% TPPO: Triphenylphosphine Oxide PP 560 Ph3PO / Triphenylphosphine oxide FR-TPPO Ceftriaxone Impurity 17 Orlistat Impurity 3(Orlistat USP RC C) Orlistat USP Related Compound C Triphenylphosphine Oxide > Triphenylphosphine oxide, 98%, for synthesis Recombinant Human TPO Protein, His Tag Recombinant Human Thrombopoietin/TPO Protein, His Tag & His Tag Orlistat Related Compound C (25 mg) riphenylphosphaneoxide ethyl (3S,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate hydrochloride triphenylphosphine oxyde Alprostadil EP Impurity K Orlistat Related Compound C (Triphenylphosphine Oxide) Triphenylphosphine Oxide (TPPO) pure, 98.5% Orlistat Related Compound C (Triphenylphosphine oxide) (1478833) Trisphenylphosphine oxide Ph3PO Orlistat Related CoMpound C triphenylphosphane oxide Triphenyl phosphorus oxide TPO Triphenylphosphinoxid TPPO TTPO K.triphenylphosphineoxide. Prostaglandin EP Impurity K Prostaglandin (Alprostadil) EP Impurity K(Triphenylphosphine oxide、Oseltamivir Impurity 41) Oseltamivir Impurity 3 (Triphenyl Phosphine Oxide) Acrivastine TPPO Oseltamivir Impurity 39 (Triphenyl Phosphine Oxide) 791-28-6 5980-60-8 C18H15OP