4-Aminobenzohydrazide
- CAS No.
- 5351-17-7
- Chemical Name:
- 4-Aminobenzohydrazide
- Synonyms
- 4-POBN;4NPhCON2;aminostimil;WLN: ZNUYQR DZ;ambenhydrazide;Amben hydrazide;TIMTEC-BB SBB007555;P-AMINOBENZHYDRAZIDE;4-AMINOBENZHYDRAZIDE;N,4-Diaminobenzamide
- CBNumber:
- CB8434256
- Molecular Formula:
- C7H9N3O
- Molecular Weight:
- 151.17
- MDL Number:
- MFCD00007606
- MOL File:
- 5351-17-7.mol
- MSDS File:
- SDS
Melting point | 225-227 °C (lit.) |
---|---|
Boiling point | 273.17°C (rough estimate) |
Density | 1.2100 (rough estimate) |
refractive index | 1.5860 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | DMF: 10 mg/ml; DMSO: 14 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml |
form | Crystals or Powder |
pka | 13.05±0.10(Predicted) |
color | White or beige |
Water Solubility | Soluble in DMSO (10 mg/ml), dilute acids, and water (partly miscible). |
BRN | 639053 |
CAS DataBase Reference | 5351-17-7(CAS DataBase Reference) |
EWG's Food Scores | 1 |
NIST Chemistry Reference | Benzoic acid, 4-amino-, hydrazide(5351-17-7) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | DG2580000 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29280000 | |||||||||
NFPA 704 |
|
4-Aminobenzohydrazide price More Price(28)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | A41909 | 4-Aminobenzoic hydrazide 95% | 5351-17-7 | 10g | $54.6 | 2024-03-01 | Buy |
Sigma-Aldrich | 475944 | Myeloperoxidase Inhibitor-I - CAS 5351-17-7 - Calbiochem | 5351-17-7 | 1g | $96.7 | 2024-03-01 | Buy |
TCI Chemical | A1211 | 4-Aminobenzohydrazide >98.0%(HPLC)(T) | 5351-17-7 | 25g | $131 | 2024-03-01 | Buy |
Alfa Aesar | A10963 | 4-Aminobenzhydrazide, 98% | 5351-17-7 | 100g | $160 | 2021-12-16 | Buy |
Alfa Aesar | A10963 | 4-Aminobenzhydrazide, 98% | 5351-17-7 | 25g | $53.9 | 2021-12-16 | Buy |
4-Aminobenzohydrazide Chemical Properties,Uses,Production
Description
4-Aminobenzoic acid hydrazide (4-ABAH) is an irreversible inhibitor of myeloperoxidase (MPO; IC50 = 0.3 μM). It reduces the production of hypochlorous acid (HOCl) induced by opsonized zymosan or phorbol 12-myristate 13-acetate (PMA; ) in isolated human neutrophils with IC50 values of 16 and 2.2 μM, respectively. 4-ABAH inhibits PMA-induced formation of neutrophil extracellular traps (NETs) in the same cells. It reduces infarct volume and the severity of neurological deficits, as well as increases survival, in a mouse model of cerebral ischemia induced by transient middle cerebral artery occlusion (MCAO) when administered at a dose of 40 mg/kg twice per day.
Chemical Properties
White or beige crystals or powder
Uses
4-Aminobenzoic hydrazide can be used as a reactant to synthesize:
- Acylhydrazone Schiff base ligand by condensation reaction with 2-acetylpyridine.
- Oligomeric transition metal complexes applicable in the fabrication of organic-inorganic hybrid devices with efficient electrical and photoelectrical properties.
- Oxovanadium(IV)-hydrazide complex as a potential radical scavenger.
Uses
4-Aminobenzhydrazide has an important role in the peroxidation activity of MPO. It is also used in enzyme preparations and in cell cultures.
4-Aminobenzohydrazide Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | info@edengenechem.com | China | 2169 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | 1015@dideu.com | China | 4088 | 58 |
Jinan Liheng Biotechnology Co., Ltd. | 15865262812 | info@lihengpharm.com | CHINA | 938 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 13349 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34571 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23555 | 58 |
View Lastest Price from 4-Aminobenzohydrazide manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2019-07-06 | 4-Aminobenzohydrazide
5351-17-7
|
US $1.00 / KG | 1KG | 99% | Customized | Career Henan Chemical Co |
- 4-Aminobenzohydrazide
5351-17-7
- US $1.00 / KG
- 99%
- Career Henan Chemical Co