ChemicalBook >> CAS DataBase List >>Apigenin 7-glucoside
Apigenin 7-glucoside
- CAS No.
- 578-74-5
- Chemical Name:
- Apigenin 7-glucoside
- Synonyms
- COSMOSIIN;APIGETRIN;APIGENIN-7-O-GLUCOSIDE;COSMETIN;APIGENIN-7-GLUCOSIDE;Apigenin-7-O-β-D-glucoside;Apigenin-7-O-β-D-glucopyranoside;Apigenin-7-O-β-D-glucopyranoside;apigenin 7-O-β-D-glucoside;Cosmosioside
- CBNumber:
- CB8468248
- Molecular Formula:
- C21H20O10
- Molecular Weight:
- 432.38
- MDL Number:
- MFCD00016787
- MOL File:
- 578-74-5.mol
- MSDS File:
- SDS
Last updated:2024-03-22 09:25:00
| Melting point | 230-237°C |
|---|---|
| Boiling point | 788.9±60.0 °C(Predicted) |
| Density | 1.642±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO (Slightly, Sonicated), Methanol (Slightly) |
| pka | 6.13±0.40(Predicted) |
| color | Pale Yellow to Yellow |
| BRN | 65669 |
| Stability | Hygroscopic |
| InChIKey | KMOUJOKENFFTPU-YUVSVTSJNA-N |
| SMILES | C1(C2=CC=C(O)C=C2)OC2=C(C(=CC(OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C2)O)C(=O)C=1 |&1:17,20,22,24,r| |
| LogP | -0.040 (est) |
| CAS DataBase Reference | 578-74-5(CAS DataBase Reference) |
| FDA UNII | 7OF2S66PCH |
Apigenin 7-glucoside price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 44692 | Apigenin 7-glucoside analytical standard | 578-74-5 | 5mg | $235 | 2024-03-01 | Buy |
| Sigma-Aldrich | 44692 | Apigenin 7-glucoside analytical standard | 578-74-5 | 25mg | $737.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | 00720585 | Apigenin 7-glucoside primary pharmaceutical reference standard | 578-74-5 | 10mg | $722 | 2024-03-01 | Buy |
| Cayman Chemical | 26813 | Apigenin 7-glucoside | 578-74-5 | 10mg | $108 | 2024-03-01 | Buy |
| Cayman Chemical | 26813 | Apigenin 7-glucoside | 578-74-5 | 50mg | $422 | 2024-03-01 | Buy |
Apigenin 7-glucoside Chemical Properties,Uses,Production
Uses
Apigenin 7-Glucoside is a by-product during the synthesis of Isorhoifolin (I819700), a naturally occurring flavonoid that was shown to exhibit potential antidiabetic, antihyperlipidemic and antioxidant effects.
Definition
ChEBI: A glycosyloxyflavone that is apigenin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.
Application
Apigenin 7-glucoside is a flavonoid with anti-inflammatory and anxiolytic activities. It inhibits LPS-induced nitric oxide production in RAW 264.7 cells when used at concentrations ranging from 0.16 to 10 μM. In vivo, apigenin 7-glucoside (10 mg/kg) reduces pulmonary edema and lung inflammation in a mouse model of LPS-induced acute lung injury. It also increases the number of entries and the time spent in the open arms of the elevated plus maze in rats, indicating anxiolytic activity.
Biological Functions
Apigenin 7-glucoside inhibited HL-60 cell growth, dose- and time-dependently, but did not cause apoptosis. The distribution of cells at different stages in the cell cycle indicated an accumulation of treated cells in the G2/M phase. Moreover, apigenin 7-glucoside induced granulocytic differentiation of HL-60 cells[1].
References
[1] Eri Nakazaki. “Proteomic study of granulocytic differentiation induced by apigenin 7-glucoside in human promyelocytic leukemia HL-60 cells.” European Journal of Nutrition 52 1 (2013): 25–35.
Synthesis of Apigenin 7-glucoside from 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-7-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)oxy]-
Apigenin 7-glucoside Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 259)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Yongjian Pharmaceutical Co.,Ltd | +86-0523-80183620 +86-17701422015 | 982552664@qq.com | China | 258 | 58 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8619164747840 | 13119157289@163.com | China | 2971 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
View Lastest Price from Apigenin 7-glucoside manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-12 | Apigenin 7-glucoside
578-74-5
|
US $0.00 / kg | 1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd | |
 |
2023-09-13 | Apigenin 7-glucoside
578-74-5
|
US $0.00 / kg | 25kg | 99% | 8 tons | Bonerge(Hunan) Lifescience Co., Ltd. | |
 |
2023-02-24 | Apigenin 7-glucoside
578-74-5
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
-
- Apigenin 7-glucoside
578-74-5
- US $0.00 / kg
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd
-
- Apigenin 7-glucoside
578-74-5
- US $0.00 / kg
- 99%
- Bonerge(Hunan) Lifescience Co., Ltd.
-
- Apigenin 7-glucoside
578-74-5
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
578-74-5(Apigenin 7-glucoside)Related Search:
4H-1-Benzopyran-4-one,7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)
Apigenin 7-glucoside SynonyMs:Apigetrin
Apigenin 7-b-D-glucoside
4H-1-Benzopyran-4-one,7-(b-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-
Apigenin 7-glucoside, >=98%
Apigetrin(Apigenin-7-O-glucoside)
5-Hydroxy-2-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
COSMIIN
7-O-BETA-D-GLUCOPYRANOSYLOXY-4',5-DIHYDROXYFLAVONE
7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 7- (.beta.-D-glucopyranosyloxy)-5-hydroxy-2-(4- hydroxyphenyl)-
APIGENIN-7-O-GLUCOSIDE WITH HPLC
Apigetrin, Cosmosiin
Apigenin 7-β-D-glucoside
4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)- (9ci)
7-o-(beta-D-Glucosyl)apigenin
Apigenin, 7-beta-D-glucopyranoside
Cosemetin
APIGENIN-7-GLUCOSIDE (COSMOSIIN)(P)
APIGENIN-7-O-GLUCOSIDE hplc
APIGENIN-7-O-GLUCOSIDE (COSMOSIIN)(P)
APIGENIN-7-O-GLUCOSIDE (COSMOSIIN)(SH)
Apigenin 7-glucoside, 98%, from Dendranthema indicum (L.) Des Moul.
5-hydroxy-2-(4-hydroxyphenyl)-7-[[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1-benzopyran-4-one
Apigenin 7-glucoside, BR
Apigenin, 7-β-D-glucopyranoside
Apigenin 7-glucoside (Apigenin-7-O-β-D-glucopyranoside
Apigenin 7-glucoside CRS
Thalictiin
5-Hydroxy-2-(4-hydroxyphenyl)-7-((2S,3S,4S,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)-4H-chromen-4-one
Apigenin 7-glucoside USP/EP/BP
5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
Apigetrin (Apigenin-7-O-β-D-glucopyranoside
7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-...
COSMETIN
COSMOSIIN
APIGENIN-7-O-GLUCOSIDE
APIGENIN-7-GLUCOSIDE
APIGETRIN
Cosmosioside
Apigenin-7-O-β-D-glucopyranoside
Apigenin-7-O-β-D-glucoside
apigenin 7-O-β-D-glucoside
Apigenin 7-O-β-glucoside
Apigenin-7-O-β-D-glucopyranoside
Apigenin 7-beta-D-glucoside
Cosmoside
578-74-5
Analytical Standards
AM to AQ
Alphabetic
Analytical Chromatography Product Catalog
chemical reagent
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract
Pharmaceutical intermediate
Tri-substituted Flavones