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4-Methoxybenzoyl chloride

4-Methoxybenzoyl chloride
4-Methoxybenzoyl chloride
Chemical Name:
4-Methoxybenzoyl chloride
Anisoylchlorid;P-ANSIOYHLORIDE;ANISOYL CHLORIDE;4-methoxybenzoyl;P-anisoylcloride;AKOS BBS-00003907;P-ANISOYL CHLORIDE;4-ANISOYL CHLORIDE;pentaanisoylchloride;4-Anisoylchloride99%
Molecular Formula:
Formula Weight:
MOL File:

4-Methoxybenzoyl chloride Properties

Melting point:
22 °C(lit.)
Boiling point:
262-263 °C(lit.)
1.260 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.581(lit.)
Flash point:
190 °F
storage temp. 
Liquid After Melting
Clear colorless to brown
Water Solubility 
It reacts in water.
Moisture Sensitive
Stable, but reacts violently with water. Ensure no moisture enters the container in which this material is stored, to prevent pressure build-up. Incompatible with water, moisture, strong bases, strong oxidizing agents.
CAS DataBase Reference
100-07-2(CAS DataBase Reference)
NIST Chemistry Reference
4-Methoxybenzoic acid chloride(100-07-2)
EPA Substance Registry System
Benzoyl chloride, 4-methoxy-(100-07-2)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  C,F
Risk Statements  14-34-67-65-63-48/20-11
Safety Statements  26-36/37/39-45-62-16
RIDADR  UN 1729 8/PG 2
WGK Germany  1
RTECS  CA0270000
HazardClass  8
PackingGroup  II
Hazardous Substances Data 100-07-2(Hazardous Substances Data)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P310 Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

4-Methoxybenzoyl chloride price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A88476 4-Methoxybenzoyl chloride 99% 100-07-2 5g $23.9 2017-11-08 Buy
Sigma-Aldrich 8.20106 4-Methoxybenzoyl chloride 100-07-2 1EA $71 2017-11-08 Buy
TCI Chemical M0721 4-Methoxybenzoyl Chloride >99.0%(GC) 100-07-2 25g $30 2017-12-01 Buy
TCI Chemical M0721 4-Methoxybenzoyl Chloride >99.0%(GC) 100-07-2 100g $44 2017-12-01 Buy
Alfa Aesar L13120 4-Methoxybenzoyl chloride, 97% 100-07-2 25g $37.6 2017-11-08 Buy

4-Methoxybenzoyl chloride Chemical Properties,Uses,Production

Chemical Properties

colourless liquid


Intermediates of Liquid Crystals


4-Methoxybenzoyl Chloride is used in the synthesis of stilbene and dihydrostilbene derivatives as potential anti-cancer agents. It is also used in the synthesis of coumarin dimers with potential HIV-1 activity.

General Description

An amber-colored crystalline solid. Melting point 72°F. Corrosive to metals and skin. Vapors may cause serious burns to the eyes.

Air & Water Reactions

Fumes in air. Reacts exothermically with water (including moisture in air or soil) to form hydrochloric acid and insoluble anisic acid [Merck 11th ed. 1989].

Reactivity Profile

ANISOYL CHLORIDE reacts exothermically with bases, including amines. Incompatible with water, strong oxidizing agents, alcohols. Sealed containers held at room temperature may explode, due to slow decomposition that builds up pressure. This situation is more dangerous with heat. May react vigorously or explosively with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Health Hazard

Vapor irritates mucous membranes. Contact of liquid with eyes or skin causes severe irritation. Ingestion causes severe irritation of mouth and stomach.

Fire Hazard

Special Hazards of Combustion Products: Irritating hydrogen chloride fumes may be formed.

4-Methoxybenzoyl chloride Preparation Products And Raw materials

Raw materials

Preparation Products

4-Methoxybenzoyl chloride Suppliers

Global( 214)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 China 19953 60
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20809 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32766 55
Anhui Royal Chemical Co., Ltd.
+86-025-86736275 CHINA 784 55
BeiLi Chemicals (Zhangjiagang) Co., Ltd. +86 (512) 5863-5988
+86 (512) 5863-5989 China 42 50
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96817 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) China 40398 62
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 China 30309 84
Danyang Wanlong Chemical Co., Ltd 0511-86810888 0511-86810995 0511-86810993
0511-86810666 China 65 55
TCI (Shanghai) Development Co., Ltd. 800-988-0390
021-67121385 China 22830 81

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