Dibutyl sebacate
- CAS No.
- 109-43-3
- Chemical Name:
- Dibutyl sebacate
- Synonyms
- PARAROSANILINE;MAGENTA;MAGENTA O;PARAFUCHSIN HYDROCHLORIDE;BASIC FUCHSIN HYDROCHLORIDE;Dibutyl Sebacate (1 mL) (AS);RUBIN;px404;ROSEIN;PX 404
- CBNumber:
- CB8737502
- Molecular Formula:
- C18H34O4
- Molecular Weight:
- 314.46
- MDL Number:
- MFCD00027218
- MOL File:
- 109-43-3.mol
- MSDS File:
- SDS
| Melting point | 205 °C (dec.)(lit.) |
|---|---|
| Boiling point | 178-179 °C3 mm Hg(lit.) |
| Density | 0.94 |
| vapor pressure | 0.001Pa at 25℃ |
| refractive index |
n |
| FEMA | 2373 | DIBUTYL SEBACATE |
| Flash point | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | hexane, toluene, ethanol and acetone: soluble |
| form | Liquid |
| Specific Gravity | 0.937 (20/4℃) |
| color | Clear |
| Odor | at 100.00 %. faint fruity oily |
| Odor Type | fruity |
| Water Solubility | 50mg/L(temperature not stated) |
| JECFA Number | 625 |
| BRN | 1798308 |
| Dielectric constant | 4.5（30℃） |
| LogP | 6.30 |
| CAS DataBase Reference | 109-43-3(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | DIBUTYL SEBACATE |
| FDA 21 CFR | 172.515; 175.105; 175.300; 175.320; 176.170; 177.2600; 178.3910; 181.27 |
| EWG's Food Scores | 1 |
| FDA UNII | 4W5IH7FLNY |
| NIST Chemistry Reference | Di-n-butyl sebacate(109-43-3) |
| EPA Substance Registry System | Dibutyl sebacate (109-43-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 40-36/37/38 | |||||||||
| Safety Statements | 36/37-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VS1150000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29171390 | |||||||||
| Toxicity | LD50 oral in rat: 14870mg/kg | |||||||||
| NFPA 704 |
|
Dibutyl sebacate price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1187091 | Dibutyl sebacate United States Pharmacopeia (USP) Reference Standard | 109-43-3 | 1ml | $491 | 2024-03-01 | Buy |
| Sigma-Aldrich | 80865 | Dibutyl sebacate analytical standard | 109-43-3 | 1ml | $72.9 | 2022-05-15 | Buy |
| Sigma-Aldrich | 8.17067 | Dibutyl sebacate NF | 109-43-3 | 1L | $246 | 2022-05-15 | Buy |
| TCI Chemical | S0023 | Dibutyl Sebacate >98.0%(GC) | 109-43-3 | 25mL | $23 | 2024-03-01 | Buy |
| TCI Chemical | S0023 | Dibutyl Sebacate >98.0%(GC) | 109-43-3 | 500mL | $70 | 2024-03-01 | Buy |
Dibutyl sebacate Chemical Properties,Uses,Production
Chemical Properties
clear liquid
Chemical Properties
Dibutyl sebacate is a clear, colorless, oily liquid with a bland to slight butyl odor.
Uses
Dibutyl sebacate (DBS) is a dibutyl ester of sebacic acid. Dibutyl sebacate can be used for plastics in use in the food packaging industry, in plastics used for medical devices, and for pharmaceutical applications. Dibutyl sebacate is also used as a desensitizer in Otto fuel II, a torpedo monopropellant.
Uses
Dibutyl sebacate has been used as a plasticizer to prepare free ethylcellulose films. It can be utilized as a core in liquid-core capsules with cross-linked alginate/polyacrylamide membrane prepared via co-extrusion jet-break-up method for the extraction of the pesticide, atrazine.
Preparation
By distillation of sebacic acid with butyl alcohol in the presence of concentrated HCl in benzene solution or by reacting butyl alcohol and sebacyl chloride
Production Methods
Dibutyl sebacate is manufactured by the esterification of n-butanol and sebacic acid in the presence of a suitable catalyst, and by the distillation of sebacic acid with n-butanol in the presence of concentrated acid.
Definition
ChEBI: Dibutyl decanedioate is a fatty acid ester.
General Description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Dibutyl sebacate is a commonly used plasticizer, which can be synthesized by the reaction of butyl alcohol and sebacyl chloride or by the distillation of sebacic acid with butyl alcohol in the presence of concentrated hydrochloric acid in benzene solution.
Flammability and Explosibility
Non flammable
Pharmaceutical Applications
Dibutyl sebacate is used in oral pharmaceutical formulations as a plasticizer for film coatings on tablets, beads, and granules, at concentrations of 10–30% by weight of polymer. It is also used as a plasticizer in controlled-release tablets and microcapsule preparations.
Dibutyl sebacate is also used as a synthetic flavor and flavor adjuvant in food products;for example,up to 5ppm is used in ice cream and nonalcoholic beverages.
Safety Profile
Mddly toxic by ingestion. Experimental reproductive effects. Combustible liquid when exposed to heat or flame; can react with oxidzing materials. To fight fire, use CO2 position it emits acrid smoke and fumes. See also ESTERS and n-BUTYL. ALCOHOL.
Safety
Dibutyl sebacate is used in cosmetics, foods, and oral pharmaceutical formulations, and is generally regarded as a nontoxic and nonirritant material. Following oral administration, dibutyl sebacate is metabolized in the same way as fats. In humans, direct eye contact and prolonged or repeated contact with the skin may cause very mild irritation. Acute animal toxicity tests and long-term animal feeding studies have shown no serious adverse effects to be associated with orally administered dibutyl sebacate.
LD50 (rat, oral): 16g/kg
storage
Dibutyl sebacate should be stored in a closed container in a cool, dry location. Dibutyl sebacate is stable under the recommended storage conditions and as used in specified applications under most conditions ofuse.Asanester,dibutylsebacatemayhydrolyzeinthe presence of water at high or low pH conditions.
Incompatibilities
Dibutyl sebacate is incompatible with strong oxidizing materials and strong alkalis.
Regulatory Status
Included in the FDA Inactive Ingredients Database (oral capsules, granules, film-coated, sustained action, and tablets). Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Dibutyl sebacate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12457 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7613 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
View Lastest Price from Dibutyl sebacate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-01-04 | Dibutyl sebacate
109-43-3
|
US $30.00-1.00 / KG | 1KG | 99%，95% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-09-06 | Dibutyl sebacate
109-43-3
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. | |
 |
2023-08-30 | Dibutyl sebacate
109-43-3
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
-
- Dibutyl sebacate
109-43-3
- US $30.00-1.00 / KG
- 99%，95%
- Henan Fengda Chemical Co., Ltd
-
- Dibutyl sebacate
109-43-3
- US $0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
-
- Dibutyl sebacate
109-43-3
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd