ChemicalBook >> CAS DataBase List >>1-Chloro-3-nitrobenzene

1-Chloro-3-nitrobenzene

CAS No.
121-73-3
Chemical Name:
1-Chloro-3-nitrobenzene
Synonyms
1-CHLORO-3-NITROBENZENE;mncb;3-CHLORONITROBENZENE;M-NITROCHLOROBENZENE;1-chloronitrobenzene;M-CHLORONITROBENZENE;1-nitro-3-chlorobenzene;1-Chloro-3;3-Chlornitrobenzol;3-NITROCHLOROBENZENE
CBNumber:
CB8747505
Molecular Formula:
C6H4ClNO2
Molecular Weight:
157.55
MDL Number:
MFCD00007202
MOL File:
121-73-3.mol
Last updated:2023-12-01 11:17:17

1-Chloro-3-nitrobenzene Properties

Melting point 43-47 °C(lit.)
Boiling point 236 °C(lit.)
Density 1.534 g/mL at 25 °C(lit.)
vapor pressure 1.9Pa at 25℃
refractive index 1.5545 (estimate)
Flash point 218 °F
storage temp. Store below +30°C.
solubility alcohol: freely soluble (hot)(lit.)
form powder to lump to clear liquid
color White or Colorless to Yellow
PH 7 (0.26g/l, H2O, 20℃)
Water Solubility INSOLUBLE
Merck 14,2151
BRN 1907947
Stability Stable. Incompatible with strong oxidizing agents, strong acids, strong reducing agents.
LogP 2.49
CAS DataBase Reference 121-73-3(CAS DataBase Reference)
FDA UNII 8XSA3GF8O1
NIST Chemistry Reference Benzene, 1-chloro-3-nitro-(121-73-3)
EPA Substance Registry System m-Chloronitrobenzene (121-73-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H302-H311-H412
Precautionary statements  P264-P270-P273-P280-P301+P312-P302+P352+P312
Hazard Codes  Xn,N,T
Risk Statements  22-50/53-23/24/25
Safety Statements  22-24/25-60-61-45-38-36/37/39-28A
RIDADR  UN 1578 6.1/PG 2
WGK Germany  2
RTECS  CZ0940000
Autoignition Temperature 500 °F
TSCA  Yes
HazardClass  6.1
PackingGroup  II
HS Code  29049085
Toxicity mouse,LD50,oral,380mg/kg (380mg/kg),Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(8), Pg. 50, 1981.
NFPA 704
1
2 0

1-Chloro-3-nitrobenzene price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 218758 1-Chloro-3-nitrobenzene 98% 121-73-3 250g $62.6 2023-01-07 Buy
TCI Chemical C0221 1-Chloro-3-nitrobenzene >99.0%(GC) 121-73-3 25g $16 2023-06-20 Buy
TCI Chemical C0221 1-Chloro-3-nitrobenzene >99.0%(GC) 121-73-3 500g $87 2023-06-20 Buy
Alfa Aesar B23423 1-Chloro-3-nitrobenzene, 98% 121-73-3 250g $43.8 2023-06-20 Buy
Alfa Aesar B23423 1-Chloro-3-nitrobenzene, 98% 121-73-3 1000g $140 2021-12-16 Buy
Product number Packaging Price Buy
218758 250g $62.6 Buy
C0221 25g $16 Buy
C0221 500g $87 Buy
B23423 250g $43.8 Buy
B23423 1000g $140 Buy

1-Chloro-3-nitrobenzene Chemical Properties,Uses,Production

Chemical Properties

Moist tan or pale yellow crystalline solid

Uses

Intermediate for dyes. 1-Chloro-3-nitrobenzene was used in the preparation of aromatic azo compounds using gold (Au) nanoparticles supported on TiO2 as a catalyst. It was also used as surrogate standard to evaluate the removal of 2,4-dinitrotoluene from contaminated soils using enhanced electrokinetic remediation.

Definition

ChEBI: 1-chloro-3-nitrobenzene is a C-nitro compound that is nitrobenzene in which one of the meta- hydrogens has been replaced by chlorine. It is a C-nitro compound and a member of monochlorobenzenes.

Production Methods

m-Chloronitrobenzene is of lesser economic importance than its ortho- and para-isomers, with no U.S. production reported. The annual production in Germany was reported to be on the order of 1000–3000 metric tons. It has limited use in the manufacturing of dyes and agricultural chemicals.
There is no information on potential exposure. Chloronitrobenzene has been detected in the surface water of the Rhine River with concentrations between 20 and 500 ng/L and in fish at levels of up to 1 mg/kg.

General Description

Pale yellow crystals. Insoluble in water.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

3-Nitrochlorobenzene can react with oxidizing materials. .

Hazard

Toxic by inhalation and ingestion. Combustible. Questionable carcinogen.

Fire Hazard

Flash point data for 3-Nitrochlorobenzene are not available. 3-Nitrochlorobenzene is probably combustible.

Flammability and Explosibility

Not classified

Safety Profile

Poison by ingestion and inhalation. It forms methemoglobin in the body and gves rise to cyanosis and blood changes. Its effects are cumulative and analogous to those of nitrobenzene. The para compound is thought to be somewhat less toxic than the ortho compound. Chemically, it is probably converted in the body to chloroaniline, whch is also poisonous. In industry, it is the dust of hs material that is most often the source of intoxication. Flammable liquid and dangerous fire hazard when exposed to heat or flame. It can react with oxidizing materials. When heated to decomposition it emits toxic fumes of Cl-, NOx, and phosgene. See also other chloronitrobenzene entries and NITRO COMPOUNDS of AROMATIC HYDROCARBONS.

Synthesis

1-Chloro-3-nitrobenzene was synthesised from 4-chloro-2-nitro-benzoic acid by adding copper iodide, triethylamine and dimethyl sulfoxide in the presence of inert gas using the Schlenk technique.
1-Chloro-3-nitrobenzene synthesis

Purification Methods

Crystallise the nitrobenzene from MeOH or 95% EtOH (charcoal), then pentane. [Beilstein 5 IV 722.]

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Mainchem Co., Ltd.
-- sarah@mainchem.com China 6572 58
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 031166536426 master@sjzsdyn.com China 2883 65
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939 shenlinxing@macklin.cn China 15873 55
Ningbo jinuo chemical co., LTD 0574-87314919 057487319282 info@nbinno.com China 7204 58
Hubei Nordina Biotechnology Co., Ltd. 19371278702 n13164103386@163.com China 2257 58
NINGBO JL NEW MATERIAL CO.,LTD 0574-88552218 18969899212 sales@jlbio-tech.cn China 635 58
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725 malulu@leyan.com China 40041 58
Hubei coward Chemical Co., Ltd 13125172151 13125172151 3508116617@qq.com China 4561 58
Nantong Zhonghe Chemical New Materials Co., Ltd 13003551299 13003551299 2369399482@qq.com China 8048 58
3-Chloro-1-nitrobenzene Benzene,1-chloro-3-nitro- Chloro-m-nitrobenzene Metachloronitrobenzene m-nitrochlorobenzene(1-chloro-3-nitrobenzene) Nitrochlorobenzene, meta- 1-chloro-3-nitro-benzen 3-NITROCHLOROBENZENE 3-Chluoronitrobenzene 3-CHLORONITROBENZENE OEKANAL, 250 MG 3-MONOCHLORONITROBENZENE 3-Chlornitrobenzol 1-CHLORO-3-NITROBENZENE pure 3-Nitro-1-chlorobenzene 1-Chloro-3-nitrobenzene,98% m-Nitrochlorobenzene Standard 1-Chloro-3-nitrobenzene, 98% 5GR 1-Chloro-3 121-73-3 3-Nitrochlorobenzene 1-CHLORO-3-NITROBENZENE For Synthesis 1-chloronitrobenzene 1-nitro-3-chlorobenzene M-CHLORONITROBENZENE 1-CHLORO-3-NITROBENZENE 3-CHLORONITROBENZENE M-NITROCHLOROBENZENE mncb 13C6]-1-Chloro-3-nitrobenzene Trazodone impurity QZT-SM-3-Z2 Ceftobiprole Impurity 3 meta-nitrochlorobenzene 121-73-3 127-73-3 88-73-8 C6H4NO2Cl 121733 NO2C6H4Cl ClC6H4NO2 Building Blocks Organic Building Blocks Nitrogen Compounds Nitro Compounds Benzene derivates Agrochemical Intermediates Intermediates of Dyes and Pigments Alpha Sort Analytical Standards AromaticsVolatiles/ Semivolatiles C CAlphabetic CHChemical Class Chemical Class ChloroAnalytical Standards Halogenated Nitro Compounds Nitrogen Compounds Organic Building Blocks