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Fluorescamine

CAS No.
38183-12-9
Chemical Name:
Fluorescamine
Synonyms
FLURAM;Fluaram;FLURAM(R);RO 20-7234;Fluorescamin;FLUORESCAMINE;FluorescamineA.R.;Fluorescamine, pure;FLURAMANALYTICAL GRADE;Fluorescamine Labeling
CBNumber:
CB8755458
Molecular Formula:
C17H10O4
Molecular Weight:
278.26
MDL Number:
MFCD00005928
MOL File:
38183-12-9.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

Fluorescamine Properties

Melting point 153-157 °C (lit.)
Boiling point 381.08°C (rough estimate)
Density 1.2661 (rough estimate)
refractive index 1.5447 (estimate)
Flash point -17 °C
storage temp. room temp
solubility acetonitrile: soluble
form powder
color off-white to yellow
Water Solubility Soluble in acetone, ethanol, chloroform, dimethylsulfoxide and acetonitrile. Slightly soluble in water.
Merck 14,4158
BRN 921143
Stability Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 38183-12-9(CAS DataBase Reference)
FDA UNII Y6859V58YW
NIST Chemistry Reference Spiro[furan-2(3h),1'(3'h)-isobenzofuran]-3,3'-dione, 4-phenyl-(38183-12-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P302+P352-P305+P351+P338
Hazard Codes  F,Xi
Risk Statements  11-36/38-66-67-36-36/37/38
Safety Statements  22-24/25-36/37-33-29-26-16-9-37/39
RIDADR  UN 1090 3/PG 2
WGK Germany  3
10-21
HS Code  29322090
NFPA 704
1
2 0

Fluorescamine price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical F0192 Fluorescamine [for HPLC Labeling] 38183-12-9 100mg $61 2024-03-01 Buy
TCI Chemical F0192 Fluorescamine [for HPLC Labeling] 38183-12-9 1g $438 2024-03-01 Buy
Alfa Aesar 043749 Fluorescamine 38183-12-9 25mg $33.8 2024-03-01 Buy
Alfa Aesar 043749 Fluorescamine 38183-12-9 100mg $107 2024-03-01 Buy
Sigma-Aldrich F9015 Fluorescamine ≥98% (TLC), powder, used for detection of primary amines 38183-12-9 100mg $133 2024-03-01 Buy
Product number Packaging Price Buy
F0192 100mg $61 Buy
F0192 1g $438 Buy
043749 25mg $33.8 Buy
043749 100mg $107 Buy
F9015 100mg $133 Buy

Fluorescamine Chemical Properties,Uses,Production

Chemical Properties

white powder

Uses

For fluorescent detection of amino acids, peptides and proteins.Fluorescamine plays an important role as a reagent for the detection of amines, peptides and proteins. It is also used as a substrate for measuring protease activity. It is utilized in the detection and quantitation of residual aminopenicillins and sulfonamides in honey by HPLC. It finds application in the determination of lisinopril in human plasma and urine.

Uses

Fluorescamine is a non-fluorescent reagent that reacts readily under mild conditions with primary amines in amino acids and peptides to form stable, highly fluorescent compounds. Reaction takes place under mild conditions. Low background due to hydrolysis.

Uses

Analytical reagent.

Synthesis Reference(s)

Journal of the American Chemical Society, 94, p. 5927, 1972 DOI: 10.1021/ja00771a084

Purification Methods

Fluram is a non-fluorescent reagent that reacts with primary amines to form highly fluorescent compounds. Purify it by dissolving (~1g) in Et2O/*C6H6 (1:1, 180 mL), washing with 1% aqueous NaHCO3 (50mL), drying (Na2SO4), and evaporating in a vacuum. Dissolve the residue in warm CH2Cl2 (5mL), dilute with Et2O (12mL) and refrigerate. Collect the solid and dry it in a vacuum. IR (CHCl3): 1810, 1745, 1722, 1625 and 1600 cm-1, and 1HNMR (CDCl3): 8.71 (s, -OHC=). [Weigele et max al. J Am Chem Soc 94 5927 1972, Weigele et al. J Org Chem 41 388 1976, Lai Methods Enzymol 47 236 1977.] Forskolin (Colforsin, Coleonol, 5-[acetyloxy]-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7, 10a-penta-methyl-[3R -{3

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View Lastest Price from Fluorescamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fluorescamine pictures 2020-02-04 Fluorescamine
38183-12-9
US $1.00 / KG 1KG 98-99.9% 100kg Career Henan Chemical Co
  • Fluorescamine pictures
  • Fluorescamine
    38183-12-9
  • US $1.00 / KG
  • 98-99.9%
  • Career Henan Chemical Co
FLUORESCAMINE FLUORESCAMINE SPRAY REAGENT FLURAM FLURAM(R) 4'-PHENYL-SPIRO[2-BENZOFURAN-1(3H),2'(3'H)-FURAN]-2',3-DIONE 4-PHENYL SPIRO-[FURAN-2(3H),1-PHTHALAN]-3,3'-DIONE 4-PHENYLSPIRO[FURAN-2(3H),1'-PHTHALAN]-3,3'-DIONE SPIRO[FURAN-2(3H),1'(3'H)-ISOBENZOFURAN]-3,3'-DIONE, 4-PHENYL- RO 20-7234 4-phenylspiro[furan-2(3H),1'(3'H)-isobenzofuran]-3,3'-dione Fluorescamine [for HPLC Labeling] FLURAM(R) (FLUORESCAMINE), FOR FLUORESCE NCE FluorescamineA.R. Fluorescamine, pure FLUORESCAMINE extrapure AR 4-Phenylspiro-[furan-2(3H),1-phthalan]-3,3μ-dione, Fluorescamine Supelco(R) TLC Spray Reagents FLURAMANALYTICAL GRADE Fluram,4-Phenylspiro-[furan-2(3H),1-phthalan]-3,3′-dione, Fluorescamine Fluorescamine,4-Phenylspiro-[furan-2(3H),1-phthalan]-3,3′-dione Fluorescamine, reagent grade Fluorescamin Fluaram FluorescaMine, pure 100MG FluorescaMine, pure 25MG FluorescaMine, pure 500MG 4-phenyl-3H,3'H-spiro[furan-2,1'-isobenzofuran]-3,3'-dione 4'-phenylspiro[2-benzofuran-3,2'-furan]-1,3'-dione Fluorescamine, For TLC analysis Fluorescamine *CAS 38183-12-9* Fluorescamine Labeling Fluorescamine, 98%, for synthesis Fluorescamine extrapure AR, ExiPlus, Multi-Compendial, 99% 4''-phenyl-3H,3''H-spiro[2-benzofuran-1,2''-furan]-3,3''-dione 4'-phenyl-3,3'-dihydrospiro[2-benzofur an-1,2'-furan]-3,3'-dione 4-Phenyl-3H,3'H-spiro[furan-2,1'-isobenzofuran]-3,3'-dione 38183-12-9 39183-12-9 C17H10O4 Amino Acids and Peptides BioChemical Amino Acid Analysis Amino Group Labeling Reagents for Fluorescence HPLC HPLC Labeling Reagents Fluorescence Detection (HPLC Labeling Reagents) Peptide Analysis and Characterization Other Fluorescent Labels Fluorescent Probes, Labels, Particles and Stains Fluorescent Labels Functional Group Reactive Labels Functional Group Reactive Labels for Flow Cytometry Detection Biochemicals and Reagents Amino Acid Analysis Reagents marker Amino Acid Analysis Amino Acid Analysis Reagents Peptide Analysis and Characterization