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O-689

CAS No.
166100-39-6
Chemical Name:
O-689
Synonyms
O-689;F-2-ME-AN;Met-F-AEA;FLUOROMETHANANDAMIDE;2-METHYL-2'-FLUORO AEA;(±)-2-Methyl Arachidonoyl-2’(+/-)-2-METHYLARACHIDONYL-2'-FLUOROETHYLAMIDE;(+/-)-2-METHYLARACHIDONOYL-2'-FLUOROETHYLAMIDE;(+/-)-2-METHYLARACHIDONOLY-2'*-FLUOROETHYLAMIDE;2-Methyl-2μ-fluoro AEA, Fluoromethanandamide, O-689
CBNumber:
CB8757735
Molecular Formula:
C23H38FNO
Molecular Weight:
363.55
MDL Number:
MFCD01862615
MOL File:
166100-39-6.mol
Last updated:2023-06-08 09:03:07

O-689 Properties

Boiling point 503.6±50.0 °C(Predicted)
Density 0.921±0.06 g/cm3(Predicted)
Flash point 14 °C
storage temp. −20°C
solubility DMF: >10 mg/ml; DMSO: >30 mg/ml; Ethanol: >100 mg/ml; Ethanol:PBS (1:2): 8.5 mg/ml; PBS (pH 7.2): <100 μg/ml
pka 14.98±0.46(Predicted)
form ethanol solution

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P305+P351+P338
Hazard Codes  F,Xi
Risk Statements  11-36/37/38
Safety Statements  7-16-26-36
RIDADR  UN 1170 3/PG 2
WGK Germany  1
NFPA 704
3
0 0

O-689 price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M1438 (±)-2-Methylarachidonoyl-2′-fluoroethylamide ≥95%, ethanol solution 166100-39-6 5mg $243 2024-03-01 Buy
Cayman Chemical 90055 (±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide ≥95% 166100-39-6 1mg $25 2024-03-01 Buy
Cayman Chemical 90055 (±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide ≥95% 166100-39-6 5mg $107 2024-03-01 Buy
Cayman Chemical 90055 (±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide ≥95% 166100-39-6 10mg $186 2024-03-01 Buy
Cayman Chemical 90055 (±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide ≥95% 166100-39-6 50mg $807 2024-03-01 Buy
Product number Packaging Price Buy
M1438 5mg $243 Buy
90055 1mg $25 Buy
90055 5mg $107 Buy
90055 10mg $186 Buy
90055 50mg $807 Buy

O-689 Chemical Properties,Uses,Production

Description

(±)-2-Methyl arachidonoyl-2''-fluoroethylamide (2-Methyl-2''-fluoro AEA) is an analog of anandamide (AEA) in which the alcohol of the ethanolamide group has been removed and replaced with a fluorine atom. This substitution confers considerably increased binding affinity for the CB1 receptor (Ki = 5.7 nM in rat brain). It also confers additional selectivity, in that binding to CB2 is decreased relative to AEA. However, the in vivo activity of 2-fluoro AEA is enhanced much less than the binding affinity, because the analog remains a good substrate for FAAH and is rapidly hydrolyzed by this enzyme. 2-Methyl-2''-fluoro AEA is further modified by the addition of an α-methyl group at the C-2 position of arachidonic acid. This substitution confers enhanced metabolic stability. 2-Methyl-2''-fluoro AEA can fully substitute for Δ9-THC in animal self-administration tests, whereas AEA and 2-fluoro AEA cannot.

O-689 Preparation Products And Raw materials

Raw materials

Preparation Products

O-689 Suppliers

Global( 13)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44894 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Suzhou Zhixin Biotechnology Co., Ltd. 0512-65118909 15162312715 sales@szzxbio.com China 2976 58
(+/-)-N-(2-FLUOROETHYL)-2-METHYL-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE O-689 (+/-)-2-METHYLARACHIDONOYL-2'-FLUOROETHYLAMIDE (+/-)-2-METHYLARACHIDONYL-2'-FLUOROETHYLAMIDE 2-METHYL-2'-FLUORO AEA F-2-ME-AN FLUOROMETHANANDAMIDE (+/-)-2-METHYLARACHIDONOLY-2'*-FLUOROETHYLAMIDE 2-Methyl-2μ-fluoro AEA, Fluoromethanandamide, O-689 (5Z,8Z,11Z,14Z)-N-(2-fluoroethyl)-2-methylicosa-5,8,11,14-tetraenamide (±)-2-Methyl Arachidonoyl-2&rsquo 5,8,11,14-Eicosatetraenamide, N-(2-fluoroethyl)-2-methyl-, (5Z,8Z,11Z,14Z)- (+/-)-2-Methylarachidonoyl-2'-fluoroethylamide >=95%, ethanol solution Met-F-AEA 166100-39-6 C23H38NOF