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(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone

(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone structure

CAS No.: 201856-53-3

Chemical Name:: (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone

Synonyms: Paclitaxel side chains;SIDE CHAINS OF PACLITAXEL--1;(3R,4S)-1-Benzoyl-3-(2-Ethoxye;1-benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone;(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone;(3R,4S)-1-benzoyl-3-(1-ethoxyethoxy)-4-phenylazetidin-2-one;(3R,4S)-3-(1-ethoxyethoxy)-4-phenyl-N-benzoyl-2-azetidinone;(3R,4S)-1-BENZOYL-3-(2-ETHOXYETHOXYL)-4-PHENYL-2-AZETIDINONE;2-Azetidinone,1-benzoyl-3-(1-ethoxyethoxy)-4-phenyl-, (3R,4S)-;(3R,4S)-1-Benzoyl-3-(1-Ethoxyethoxy)-4-Phenyl-2-AzetidinoneCasNo.

CBNumber:: CB8854814

Molecular Formula:: C20H21NO4

Molecular Weight:: 339.39

MDL Number:: MFCD09752076

MOL File:: 201856-53-3.mol

Last updated:2023-05-04 15:13:49

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(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone Properties

Boiling point	464.8±55.0 °C(Predicted)
Density	1.22
storage temp.	2-8°C
pka	-4.83±0.60(Predicted)
CAS DataBase Reference	201856-53-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H335-H315
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone price More Price(11)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth Carbosynth	FB148182	(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone	201856-53-3	50mg	$63	2021-12-16	Buy
Biosynth Carbosynth	FB148182	(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone	201856-53-3	100mg	$110	2021-12-16	Buy
Biosynth Carbosynth	FB148182	(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone	201856-53-3	250mg	$220	2021-12-16	Buy
AK Scientific	Q749	(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone	201856-53-3	250mg	$347	2021-12-16	Buy
Biosynth Carbosynth	FB148182	(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone	201856-53-3	500mg	$380	2021-12-16	Buy

Product number	Packaging	Price	Buy
FB148182	50mg	$63	Buy
FB148182	100mg	$110	Buy
FB148182	250mg	$220	Buy
Q749	250mg	$347	Buy
FB148182	500mg	$380	Buy

(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone Chemical Properties,Uses,Production

Uses

(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone is an investigational intermediate chemical for Paclitaxel and Docetaxel.

Synthesis

To a solution of 2.35 g (10 mmol) of cis-3-(1-ethoxyethoxy)-4-phenylazetidin-2-one in 40 mL of THF at -78° C, was added 6.1 mL (10.07 mmol) of a 1.65M solution of n-butyllithium in hexane. The mixture was stirred for 10 min at -78° C and a solution of 1.42 g (10.1 mmol) of benzoyl chloride in 10 mL of THF was added. The mixture was stirred at -78° C for 1 h diluted with 70 mL of saturated aqueous sodium bicarbonate and extracted with three 50 mL portions of ethyl acetate. The combined ethyl acetate extracts were dried over sodium sulfate and concentrated to give 3.45 g of oil. Chromatography of the oil on silica gel eluted with ethyl acetate/hexane gave 3.22 g (95%) of (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone as a colorless oil.

(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone synthesis

Synthesis of (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone from Benzoyl chloride and (3R,4S)-3-(1-Ethoxyethoxy)-4-phenyl-2-azetidinone

(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone Preparation Products And Raw materials

Raw materials

(3R,4S)-3-(1-Ethoxyethoxy)-4-phenyl-2-azetidinone Benzoyl chloride

Preparation Products

(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone Suppliers

Global( 76)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Shanghai finete Pharmaceutical Co., Ltd.	+86-18221039705		CHINA	139	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58
Longyan Tianhua Biological Technology Co., Ltd	0086 18039857276 18039857276		CHINA	2783	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9702	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai finete Pharmaceutical Co., Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
SIMAGCHEM CORP	58
Longyan Tianhua Biological Technology Co., Ltd	58
AFINE CHEMICALS LIMITED	58
Finetech Industry Limited	58

View Lastest Price from (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-22	(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone 201856-53-3	US $0.00 / Kg/Bag	2Kg/Bag	99% up, High Density	20 tons	Sinoway Industrial co., ltd.
2020-11-18	(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone 201856-53-3	US $63.00 / KG	1KG	99	1000KG	Longyan Tianhua Biological Technology Co., Ltd
2020-02-14	(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone 201856-53-3	US $7.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
201856-53-3
US $0.00 / Kg/Bag
99% up, High Density
Sinoway Industrial co., ltd.

(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
201856-53-3
US $63.00 / KG
99
Longyan Tianhua Biological Technology Co., Ltd

(3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone
201856-53-3
US $7.00 / KG
99%
Career Henan Chemical Co

201856-53-3((3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone)Related Search:

PHENYL VALERATE 2-Ethoxyethanol Ethoxyethyne Diethoxymethyl acetate Benzoyl peroxide

Benzoyl chloride Ethyl vinyl ether Ethoxyquin DIETHOXYMETHANE PHENYL RESIN

(3R,4S)-3-Hydroxy-4-phenyl-2-azetidinone Phenylacetic acid Docetaxel Cyclobutanone 2-Azetidinone

Docetaxel PACLITAXEL SIDE CHAIN NO 1 Paclitaxel

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(3R,4S)-1-Benzoyl-3-(1-Ethoxyethoxy)-4-Phenyl-2-AzetidinoneCasNo. (3R,4S)-1-BENZOYL-3-(2-ETHOXYETHOXYL)-4-PHENYL-2-AZETIDINONE (3R,4S)-3-(1-ethoxyethoxy)-4-phenyl-N-benzoyl-2-azetidinone (3R,4S)-1-Benzoyl-3-(2-Ethoxye DOCETAXEL SIDE CHAIN / (3R,4S)-1-BENZOYL-3-(2-ETHOXYETHOXY)-4-PHENYL-2-PHENYL-AZETIDIONE (3R,4S)-1-BENZOYL-3-(2-ETHOXYETHOXYL) -4-PHENYL-2-AZETIDINONE 97% SIDE CHAINS OF PACLITAXEL--1 (3R,4S)-1-benzoyl-3-(1-ethoxyethoxy)-4-phenylazetidin-2-one (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone 1-benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone Paclitaxel side chains 2-Azetidinone,1-benzoyl-3-(1-ethoxyethoxy)-4-phenyl-, (3R,4S)- Paclitaxel Side Chain (Azelidinone) 1-Benzoyl-3-(1-Ethoxyethoxy)-4-Phenyl-2-Azetidinone (3R, 4S) -1-Benzoyl-3- (1-ethoxyethoxy) -4-phenyl-2-azacyclobutanone 201856-53-3 Intermediates