8-Hydroxyquinoline-N-oxide
- CAS No.
- 1127-45-3
- Chemical Name:
- 8-Hydroxyquinoline-N-oxide
- Synonyms
- NSC 21656; NSC 2165;2-METHYLOXINE;OXINE N-OXIDE;1-Oxy-quinolin-8-ol;TIMTEC-BB SBB009099;8-Hydroxyquinoline-N;8-QUINOLINOL-1-OXIDE;8-QUINOLINOL N-OXIDE;Quinolin-8-ol N-oxide
- CBNumber:
- CB9112579
- Molecular Formula:
- C9H7NO2
- Molecular Weight:
- 161.16
- MDL Number:
- MFCD00006739
- MOL File:
- 1127-45-3.mol
- MSDS File:
- SDS
| Melting point | 135-138 °C (lit.) |
|---|---|
| Boiling point | 267 °C(lit.) |
| Density | 1.2480 (rough estimate) |
| refractive index | 1.5050 (estimate) |
| Flash point | 139 °C |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Soluble in Acetone, Chloroform, Dichloromethane, Ethyl Acetate and Methanol |
| form | Solid |
| pka | 6.03±0.30(Predicted) |
| color | Yellow |
| BRN | 128737 |
| CAS DataBase Reference | 1127-45-3(CAS DataBase Reference) |
| FDA UNII | TMI4LD989P |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317-H351b-H372 | |||||||||
| Precautionary statements | P201-P202-P260-P264b-P270-P272-P280g-P302+P352-P308+P313-P363-P403-P501c | |||||||||
| Hazard Codes | N,Xi | |||||||||
| Risk Statements | 50/53-36/37/38 | |||||||||
| Safety Statements | 60-61-24/25-22-36/37/39-27-26 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VC8238500 | |||||||||
| F | 3-10 | |||||||||
| HS Code | 29334900 | |||||||||
| NFPA 704 |
|
8-Hydroxyquinoline-N-oxide price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 122335 | 8-Quinolinol N-oxide 98% | 1127-45-3 | 10g | $126.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | 122335 | 8-Quinolinol N-oxide 98% | 1127-45-3 | 5g | $175 | 2023-06-20 | Buy |
| TCI Chemical | H1272 | 8-Hydroxyquinoline N-Oxide >98.0%(HPLC)(T) | 1127-45-3 | 5g | $48 | 2024-03-01 | Buy |
| TCI Chemical | H1272 | 8-Hydroxyquinoline N-Oxide >98.0%(HPLC)(T) | 1127-45-3 | 25g | $151 | 2024-03-01 | Buy |
| TRC | H953270 | 8-Hydroxyquinoline N-Oxide | 1127-45-3 | 5g | $80 | 2021-12-16 | Buy |
8-Hydroxyquinoline-N-oxide Chemical Properties,Uses,Production
Description
A quinoline derivative that displays mutagenic activity. It suppresses luminescence of an indicator bacterium that is named Photobacterium phosphoreum. This chemical forms two kinds of complexes with palladium (II) and Gold (III). One kind is an ion-associated compound containing hydrogen bond and hte other is the six membered metal chelates containing metal-oxygen bonds.
Chemical Properties
Yellow Crystalline Solid
Uses
A quinoline derivative; shows mutagenic activity.
Definition
ChEBI: 8-hydroxyquinoline N-oxide is a quinoline N-oxide carrying a hydroxy substituent at position 8. It is a monohydroxyquinoline and a quinoline N-oxide. It is functionally related to a quinolin-8-ol. It is a conjugate acid of an 8-hydroxyquinoline N-oxide(1-).
General Description
8-Quinolinol N-oxide is a toxicant which can suppress luminescence of an indicator bacterium Photobacterium phosphoreum. It forms two types of complexes with gold(III) and palladium(II): type I are ion-associated compounds containing hydrogen bond and the other is the six-membered metal chelates containing metal-oxygen bonds.
Synthesis
8-hydroxyquinoline-N-oxide was synthesized from 8-hydroxyquinoline. A stirred solution of 8-hydroxyquinoline (25.00 g, 172.2 mmol) in 550 ml of CHCl3 was cooled to 0° C., and 3 -chloroperoxybenzoic acid (40.00 g, 80% Tech. grade *0.231 mmol=0.185 mmol) was added slowly over 3 minutes. The solution was kept at 0° C. and stirred for 3 hours. During this period, the 3-chlorobenzoic acid byproduct precipitated. The 3-chlorobenzoic acid was removed by filtration and the orange filtrate was concentrated to dryness and the remaining solid was triturated with 2% NH40 H (2*200 ml). The solid was isolated on a frit and washed with H2O.
8-Hydroxyquinoline-N-oxide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Triumpharm Co.,Ltd | +86-02586182925 +86-15105172550 | info@triumpharm.com | China | 129 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2966 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Hebei shuoxi biotechnology co. LTD | +8613081092107 | CHINA | 968 | 58 | |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
View Lastest Price from 8-Hydroxyquinoline-N-oxide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-18 | 8-Hydroxyquinoline-N-oxide
1127-45-3
|
US $5.00 / kg | 1kg | 99% | 300tons | Hebei Dangtong Import and export Co LTD | |
 |
2023-06-19 | 8-Hydroxyquinoline-N-oxide
1127-45-3
|
US $100.00 / kg | 1kg | 99% | 1000tons | Henan Bao Enluo International TradeCo.，LTD | |
 |
2023-02-03 | 8-Hydroxyquinoline-N-oxide
1127-45-3
|
US $45.00 / kg | 1kg | 99% | 5000 tons | Hebei Duling International Trade Co. LTD |
-
- 8-Hydroxyquinoline-N-oxide
1127-45-3
- US $5.00 / kg
- 99%
- Hebei Dangtong Import and export Co LTD
-
- 8-Hydroxyquinoline-N-oxide
1127-45-3
- US $100.00 / kg
- 99%
- Henan Bao Enluo International TradeCo.，LTD
-
- 8-Hydroxyquinoline-N-oxide
1127-45-3
- US $45.00 / kg
- 99%
- Hebei Duling International Trade Co. LTD
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