ChemicalBook >> CAS DataBase List >>1,3-Dimethylbarbituric acid
1,3-Dimethylbarbituric acid
- CAS No.
- 769-42-6
- Chemical Name:
- 1,3-Dimethylbarbituric acid
- Synonyms
- 1,3-DIMETHYLPYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE;1,3-DiMethyl-;1,3-Dimethylbarbituric;2,4,6(1H,3H,5H)-Pyrimidinetrione, 1,3-dimethyl-;6(1H;AKOS B029702;1,3-Dimethylbarbitur;Dimethylbarbituric acid;1,3-dimethylbarbiturates;1,3-DIMETHYLBARBITURIC ACID
- CBNumber:
- CB9121414
- Molecular Formula:
- C6H8N2O3
- Molecular Weight:
- 156.14
- MDL Number:
- MFCD00006675
- MOL File:
- 769-42-6.mol
- MSDS File:
- SDS
Last updated:2023-11-07 17:33:14
| Melting point | 121-123 °C (lit.) 121-123 °C |
|---|---|
| Boiling point | 228.1±23.0 °C(Predicted) |
| Density | 1.322±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | hot water: soluble0.5g/10 mL, clear, colorless to faintly yellow |
| form | Crystalline Powder |
| pka | pK1:4.68(+1) (25°C) |
| color | White/cream/pale yellow |
| Water Solubility | Soluble in water. |
| BRN | 139810 |
| CAS DataBase Reference | 769-42-6(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,3-Dimethylbarbituric acid(769-42-6) |
| EPA Substance Registry System | 2,4,6(1H,3H,5H)-Pyrimidinetrione, 1,3-dimethyl- (769-42-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H318 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312-P305+P351+P338-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-41 | |||||||||
| Safety Statements | 26-36/39 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
1,3-Dimethylbarbituric acid price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 39565 | 1,3-Dimethylbarbituric acid ≥99.0% (T) | 769-42-6 | 50g | $88.9 | 2024-03-01 | Buy |
| Sigma-Aldrich | 39565 | 1,3-Dimethylbarbituric acid ≥99.0% (T) | 769-42-6 | 250g | $219 | 2024-03-01 | Buy |
| TRC | D463650 | 1,3-Dimethylbarbituric acid | 769-42-6 | 25g | $2240 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | JK127134 | 1,3-Dimethylbarbituric acid 98% | 769-42-6 | 500g | $178 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0017293 | 1,3-DIMETHYLBARBITURIC ACID 95.00% | 769-42-6 | 1G | $750.75 | 2021-12-16 | Buy |
1,3-Dimethylbarbituric acid Chemical Properties,Uses,Production
Chemical Properties
Yellow or brownish powder
Uses
1,3-Dimethyl Barbituric Acid (Urapidil Impurity 4) is a derivative of Barbituric acid. All of the barbituric acid derivatives which have been reported to have pronounced hypnotic activity are disubstituted in the 5-position.
Uses
1,3-Dimethylbarbituric acid is used as a catalyst in the Knoevenagel condensation of a series of aromatic aldehydes. It is also used in the synthesis of 5-aryl-6-(alkyl- or aryl-amino)-1,3-dimethylfuro [2,3-d]pyrimidine derivatives and enantioselective synthesis of isochromene pyrimidinedione derivatives.
General Description
1,3-Dimethylbarbituric acid (1,3-Dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione) is an active methylene compound. It undergoes hollow Pd6 water-soluble cage, [{(tmen)Pd}6(timb)4](NO3)12 (tmen= N,N,N′,N′-tetramethylethylenediamine, timb=1,3,5-tris(1-imidazolyl)benzene)-catalyzed Knoevenagel condensation reaction with pyrene-1-carboxaldehyde. It undergoes self-sorted Pd7 molecular boat having an internal nanocavity (catalyst)-assisted Knoevenagel condensation reaction with various aromatic aldehydes. It has been synthesized by reacting 1,3-dimethylurea, malonic acid and acetic anhydride in acetic acid. It is widely used for the synthesis of various synthetic intermediates and heterocyclic compounds.
Purification Methods
Crystallise the acid from water and sublime it in a vacuum. Also purify it by dissolving 10g in 100mL of boiling CCl4/CHCl3 (8:2) (1g charcoal), filtering and cooling to 25o. Dry it in vacuo [Kohn et al. Anal Chem 58 3184 1986]. [Beilstein 24 III/IV 1875.]
Synthesis of 1,3-Dimethylbarbituric acid from Dihydro-1,3-dimethyl-2-thioxo-4,6(1H,5H)-pyrimidinedione
1,3-Dimethylbarbituric acid Preparation Products And Raw materials
Raw materials
Preparation Products
6-[N-(2-Hydroxyethyl)amino]-1,3-dimethyl-2,4(1H,3H)-dione
ISOCAFFEINE
1,3-dimethyl-5-(thiophen-2-ylmethylene)pyrimidine-2,4,6(1H,3H,5H)-trione
7-AMINO-1,3-DIMETHYL-2,4-DIOXO-1,2,3,4-TETRAHYDRO-5H-PYRANO[2,3-D]PYRIMIDINE-5,5,6-TRICARBONITRILE
5-((1H-indol-3-yl)methylene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione
2-[(1,3-dimethyl-2,4,6-trioxo-1,3-diazinan-5-ylidene)methyl]phenyl acetate
1,3-dimethyl-5-[(4-oxo-4H-chromen-3-yl)methylidene]-1,3-diazinane-2,4,6-trione
1,3-DIMETHYL-5-([4-(METHYLSULFANYL)PHENYL]METHYLENE)-2,4,6(1H,3H,5H)-PYRIMIDINETRIONE
6-chloro-1,3-dimethyl-5-nitro-pyrimidine-2,4-quinone
1,3-DIMETHYL-5-[(DIMETHYLAMINO)METHYLENE]2,4,6-(1H,3H,5H)-TRIOXOPRYIMIDINE
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Global( 370)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2967 | 58 |
| weifang runzhong fine chemical co., ltd | 536-7868377 +8618653686003 | sq@runzhongchem.com | China | 187 | 58 |
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| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Wuhan Quanjinci New Material Co.,Ltd. | +8615271838296 | kyra@quanjinci.com | China | 1532 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
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| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 6992 | 58 |
View Lastest Price from 1,3-Dimethylbarbituric acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-23 | 1,3-Dimethylbarbituric acid
769-42-6
|
US $0.00 / Kg/Drum | 1KG | 99% | 100mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2024-04-23 | 1,3-Dimethylbarbituric acid
769-42-6
|
US $100.00-40.00 / kg | 100kg | 99.99% | 100Tons | Hebei Dangtong Import and export Co LTD | |
 |
2023-11-29 | 1,3-Dimethylbarbituric acid
769-42-6
|
US $70.00 / kg | 1kg | 0.99 | 1000000tons | Wuhan Quanjinci New Material Co.,Ltd. |
-
- 1,3-Dimethylbarbituric acid
769-42-6
- US $0.00 / Kg/Drum
- 99%
- Jinan Finer Chemical Co., Ltd
-
- 1,3-Dimethylbarbituric acid
769-42-6
- US $100.00-40.00 / kg
- 99.99%
- Hebei Dangtong Import and export Co LTD
-
- 1,3-Dimethylbarbituric acid
769-42-6
- US $70.00 / kg
- 0.99
- Wuhan Quanjinci New Material Co.,Ltd.
769-42-6(1,3-Dimethylbarbituric acid)Related Search:
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TIANFU-CHEM 1,3-Dimethylbarbituric acid
1,3-DIMETHYLPYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE
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769-42-6
Pyrimidines
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