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Ropinirole

CAS No.
91374-21-9
Chemical Name:
Ropinirole
Synonyms
Ropinirole base;SKF-101468;ROPINIROLE;Ropinirolum;ROPINIROLE 99%;RSYYRopinirole;Unii-030pyr8953;SKF-101468A:ReQuip;Ropinirole USP/EP/BP;Ropinirole Impurity 22
CBNumber:
CB9137570
Molecular Formula:
C16H24N2O
Molecular Weight:
260.37
MDL Number:
MFCD00864147
MOL File:
91374-21-9.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:43

Ropinirole Properties

Melting point 243-250°C
Boiling point 410.5±45.0 °C(Predicted)
Density 1.040±0.06 g/cm3(Predicted)
pka 14.17±0.20(Predicted)
CAS DataBase Reference 91374-21-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 030PYR8953
ATC code N04BC04

Pharmacokinetic data

Protein binding 10-40%
Excreted unchanged in urine <10%
Volume of distribution 8(L/kg)
Biological half-life 6 / -

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H412-H302
Precautionary statements  P273-P501-P264-P270-P301+P312-P330-P501

Ropinirole price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 3680 Ropinirole ≥99%(HPLC) 91374-21-9 10 $87 2021-12-16 Buy
Tocris 3680 Ropinirole ≥99%(HPLC) 91374-21-9 50 $363 2021-12-16 Buy
American Custom Chemicals Corporation API0004095 ROPINIROLE 95.00% 91374-21-9 10MG $612.44 2021-12-16 Buy
Medical Isotopes, Inc. D34162 Ropinirole-d14 HCl 91374-21-9 1mg $625 2021-12-16 Buy
American Custom Chemicals Corporation API0004095 ROPINIROLE 95.00% 91374-21-9 50MG $823.46 2021-12-16 Buy
Product number Packaging Price Buy
3680 10 $87 Buy
3680 50 $363 Buy
API0004095 10MG $612.44 Buy
D34162 1mg $625 Buy
API0004095 50MG $823.46 Buy

Ropinirole Chemical Properties,Uses,Production

Uses

Antiparkinsonian (D2receptor agonist).

Definition

ChEBI: Ropinirole is a member of indolones and a tertiary amine. It has a role as a dopamine agonist, an antiparkinson drug, a central nervous system drug and an antidyskinesia agent.

brand name

Requip (GlaxoSmithKline).

Synthesis Reference(s)

Journal of Medicinal Chemistry, 28, p. 1533, 1985 DOI: 10.1021/jm00148a028

Clinical Use


Anti-Parkinson agent
Restless legs syndrome (RLS)

Drug interactions

Potentially hazardous interactions with other drugs
Antipsychotics: antagonism of anti-Parkinsonian effect - avoid.
Metoclopramide: antagonism of anti-Parkinsonian effect - avoid.
Oestrogens: concentration increased.

Metabolism

Ropinirole is hepatically metabolised by the cytochrome P450 enzyme, CYP1A2, and excreted in the urine as inactive metabolites.

Ropinirole Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 151)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Xi'an MC Biotech, Co., Ltd.
029-89275612 +8618991951683 mcbio_sales@163.com China 2255 58
Shijiazhuang Gantuo Biotechnology Co., Ltd
+8613373514458 gantuo02@cngantuo.com China 218 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29831 58
AFINE CHEMICALS LIMITED
0571-85134551 info@afinechem.com CHINA 15377 58
Baoji Guokang Bio-Technology Co., Ltd.
0917-3909592 13892490616 gksales1@gk-bio.com China 9340 58
Baoji Guokang Healthchem co.,ltd
+8615604608665 15604608665 dominicguo@gk-bio.com CHINA 9427 58

View Lastest Price from Ropinirole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ropinirole pictures 2023-06-26 Ropinirole
91374-21-9
US $200.00 / kg 1kg 99% 1000kg/Month Hebei Mingeng Biotechnology Co., Ltd
Ropinirole pictures 2023-04-11 Ropinirole
91374-21-9
US $100.00 / mg 25mg 99% 1000g Shijiazhuang Gantuo Biotechnology Co., Ltd
Ropinirole pictures 2021-11-02 Ropinirole
US $64.00 / g 1g 99% 10kg Baoji Guokang Healthchem co.,ltd
  • Ropinirole pictures
  • Ropinirole
    91374-21-9
  • US $200.00 / kg
  • 99%
  • Hebei Mingeng Biotechnology Co., Ltd
  • Ropinirole pictures
  • Ropinirole
    91374-21-9
  • US $100.00 / mg
  • 99%
  • Shijiazhuang Gantuo Biotechnology Co., Ltd
  • Ropinirole pictures
  • Ropinirole
  • US $64.00 / g
  • 99%
  • Baoji Guokang Healthchem co.,ltd
ROPINIROLE 4-(2-dipropylaminoethyl)-1,3-dihydroindol-2-one ROPINIROLE: ROPINIROLE HYDROCHLORIDE ROPINIROLE INTERMEIDATES: ROPINIROLE 99% 4-[2-(Dipropylamino)ethyl]-1,3-dihydrcr2H-indol-2-one SKF-101468 SKF-101468A:ReQuip 4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one 4-[2-(Dipropylamino)ethyl]indoline-2-one 2H-Indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro- 91374-20-8 (Hydrochloride) Ropinirol [inn-spanish] Ropinirolum Ropinirolum [inn-latin] Unii-030pyr8953 Ropinirole(Hydrochloride form) (3S)-3-bromo-2-oxobutanoic acid Ropinirole USP/EP/BP Ropinirole Impurity 22 Ropinirole Impurity 23 Ropinirole Impurity 24 4-(2-(Dipropylamino)ethyl)indolin-2-one Ropinirole base Ropinirole (SKF-101468) RSYYRopinirole RSYYIbrutinib Impurity 141 91374-21-9 91374-58-8 C16H24N2O API ACTIVE PHARMACEUTICAL INGREDIENTS Pharmaceutical material and intermeidates Antiparkinsonian