ChemicalBook >> CAS DataBase List >>Stanolone

Stanolone

CAS No.
521-18-6
Chemical Name:
Stanolone
Synonyms
DHT;DIHYDROTESTOSTERONE;ANDROSTANOLONE;5α-Dihydrotestosterone;5α-DHT;Anaboleen;Andractim;4-dihydrotestosterone;5ALPHA-DIHYDROTESTOSTERONE;5ALPHA-ANDROSTAN-17BETA-OL-3-ONE
CBNumber:
CB9181225
Molecular Formula:
C19H30O2
Molecular Weight:
290.45
MDL Number:
MFCD00003667
MOL File:
521-18-6.mol
Last updated:2024-04-12 23:00:59

Stanolone Properties

Melting point 178-183 °C
alpha 27 º
Boiling point 372.52°C (rough estimate)
Density 1.0320 (rough estimate)
refractive index 1.4709 (estimate)
Flash point 9℃
storage temp. 2-8°C
solubility Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
pka 15.08±0.60(Predicted)
Water Solubility 344.3g/L(temperature not stated)
Merck 13,8872
BRN 2056371
InChIKey NVKAWKQGWWIWPM-ABEVXSGRSA-N
CAS DataBase Reference 521-18-6(CAS DataBase Reference)
NCI Dictionary of Cancer Terms androstanolone; DHT; dihydrotestosterone
FDA UNII 08J2K08A3Y
NCI Drug Dictionary dihydrotestosterone
ATC code A14AA01,G03BB02
NIST Chemistry Reference Stanolone(521-18-6)
EPA Substance Registry System Androstan-3-one, 17-hydroxy-, (5.alpha.,17.beta.)- (521-18-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H302-H351-H360FD-H410
Precautionary statements  P202-P264-P270-P273-P301+P312-P308+P313
Hazard Codes  Xn,T,F
Risk Statements  61-40-39/23/24/25-23/24/25-11
Safety Statements  53-36/37/39-45-36/37-16
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  3
RTECS  BV8052000
NFPA 704
0
3 0

Stanolone price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR9196 5α-Androstan-17β-ol-3-one certified reference material, TraceCERT? 521-18-6 100MG $691 2024-03-01 Buy
Sigma-Aldrich D-073 5α-Dihydrotestosterone (DHT) solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? 521-18-6 1mL $142 2024-03-01 Buy
Sigma-Aldrich A8380 5α-Androstan-17β-ol-3-one ≥97.5% 521-18-6 1g $86 2024-03-01 Buy
Sigma-Aldrich A8380 5α-Androstan-17β-ol-3-one ≥97.5% 521-18-6 10g $515 2024-03-01 Buy
Cayman Chemical 15874 Dihydrotestosterone ≥97% 521-18-6 25mg $275 2024-03-01 Buy
Product number Packaging Price Buy
PHR9196 100MG $691 Buy
D-073 1mL $142 Buy
A8380 1g $86 Buy
A8380 10g $515 Buy
15874 25mg $275 Buy

Stanolone Chemical Properties,Uses,Production

Description

Stanolone is well known as dihydrotestosterone (DHT), which is an endogenous androgen sex steroid and hormone. It is an agonist of the androgen receptor (AR). It plays important physiological role in sexual differentiation, maturation of the penis and scrotum, hair, sebum production and development and maintenance of the prostate gland and seminal vesicles. It is mainly used for the treatment of male hypogonadism, androgen deficiency of severe illness, androgen deficiency of ageing and microphallus in infancy.

Chemical Properties

White Crystalline Solid

Originator

Neodrol,Pfizer,US,1953

Uses

Stanolone is a potent androgenic metabolite of testosterone that It is Controlled substance. It was created for the treatment of muscle wasting disease, and osteoporosis. It is a powerful anabolic steroid, which is similar to the body's naturally produced Dihydrotestosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure androgenic steroid.

Definition

ChEBI: Stanolone is a 17beta-hydroxy steroid that is testosterone in which the 4,5 double bond has been reduced to a single bond with alpha-configuration at position 5. It has a role as an androgen, a human metabolite, a Daphnia magna metabolite and a mouse metabolite. It is a 17beta-hydroxy steroid, a 17beta-hydroxyandrostan-3-one and a 3-oxo-5alpha-steroid. It derives from a hydride of a 5alpha-androstane.

Manufacturing Process

A solution of 1.0 g of 3,17-androstandione in 50 ml of methanol and containing 1 g of selenium dioxide, was allowed to remain in an ice-chest overnight. The formed 3,3-dimethoxyandrostan-17-one was not separated. 1 g of solid potassium hydroxide and 2.5 g of sodium borohydride in 2.5 ml of water were added and the mixture allowed to react at room temperature for 24 hours. The solution was then poured into a large excess of water, extracted with methylene chloride, the organic layer dried and evaporated to a residue. The residue was dissolved in ether, and a small amount of selenium removed by filtration. The ether was boiled off and the organic material dissolved in 100 ml of boiling acetone. 25 ml of diluted hydrochloric acid were added, the solution boiled for 5 minutes and then allowed to cool. Upon crystallization, 0.85 g of androstan-17β-ol-3-one was obtained, melting point 175°C to 178°C.

Therapeutic Function

Androgen

General Description

Dihydrotestosterone (Item No. 15874) is an analytical reference standard categorized as an anabolic androgenic steroid. Anabolic steroids, including dihydrotestosterone, have been used to enhance physical performance in athletes. Dihydrotestosterone is regulated as a Schedule III compound in the United States. This product is intended for research and forensic applications.

Side effects

In rare cases, serious and even fatal cases of liver problems have developed during treatment with stanozolol. Contact your doctor immediately if you experience abdominal pain, light-colored stools, dark-colored urine, unusual fatigue, nausea or vomiting, or yellowing of the skin or eyes. These may be early signs of liver problems.
Serious side effects: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); swelling of the arms or legs (especially ankles); frequent or persistent erections, or breast tenderness or enlargement (male patients); or voice changes (hoarseness, deepening), hair loss, facial hair growth, clitoral enlargement, or menstrual irregularities (female patients).
Common stanozolol side effects may include: new or worsening acne; difficulty sleeping; headache; or changes in sexual desire.

References

https://en.wikipedia.org/wiki/Dihydrotestosterone#Medical_use
Swerdloff, R. S., and C. Wang. "Dihydrotestosterone: a rationale for its use as a non-aromatizable androgen replacement therapeutic agent."Baillieres Clin Endocrinol Metab 12.3(1998):501.

58-22-0
521-18-6
Synthesis of Stanolone from Testosterone

Stanolone Preparation Products And Raw materials

Global( 299)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Harvest Chemical CO.,Ltd
+86-13129915771 +86-15623179893 wendy@hb-harvestchem.com China 931 58
Wuhan Aoliqisi New Material Technology Co., Ltd.
+86-13545906766; +8613545906766 sales@whaop.com China 265 58
Wuhan Golt Biotech Co., Ltd.
+8615389281203 maria@goltbiotech.com China 980 58
Hebei Bonster Technology Co.,Limited
+8613315996897 bsterltd.wendy@gmail.com China 796 58
Hebei Gongyuan New Material Technology Co., Ltd.
+8617331136198 Grace@hebeisyjl.com China 497 58
Hebei Shengyuan Jinlong Import and Export Co. LTD
+8617367750398 info@hebeisyjl.com China 1867 58
Hebei Yinsheng Technology Co., Ltd.
+86-17331136691 lemon@hbyinsheng.com China 622 58
Anhui Yisheng Technology Co., LTD
+86-19355901310 +86-19355901310 alice@ah-yisheng.com China 333 58
Shanghai Longyu Biotechnology Co., Ltd.
+8615821988213 info@longyupharma.com China 2531 58
Shanghai Getian Industrial Co., LTD
+undefined15373193816 mike@ge-tian.com China 272 58

Related articles

View Lastest Price from Stanolone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Androstanolone/Stanolone/dihydrotestosterone/DHT pictures 2024-04-23 Androstanolone/Stanolone/dihydrotestosterone/DHT
521-18-6
US $35.00 / Box 1Box 99.99% 10000000000 zhuzhou dingcheng meihei comestic co.,ltd
Stanolone (androstanolone)  pictures 2024-04-23 Stanolone (androstanolone)
521-18-6
US $0.00 / G 1G 99% 20 CONTIDE BIOTECH CO.,LTD
Androstanolone;Stanolone;dihydrotestosterone;DHT pictures 2024-04-23 Androstanolone;Stanolone;dihydrotestosterone;DHT
521-18-6
US $10.00-300.00 / g 1g 99.99% 500kg Wuhan Cell Pharmaceutical Co., Ltd
(5S,8R,9S,10S,13S,14S,17S)-17-Hydroxy-10,13-dimethyltetradecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one 5α-androstan-17β-ol-3-one solution,100ppm (8R,9S,10S,13S,14S)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one (5-alpha,17-beta)-17-hydroxyandrostan-3-one (5alpha,17beta)-17-Hydroxy-androstan-3-one 17beta-Hydroxy-3-androstanone 17-beta-hydroxy-5-alpha-androstan-3-on 17-hydroxy-,(5-alpha,17-beta)-androstan-3-on 17-Hydroxyandrostan-3-one 5A-Androstan-3-on-17B-ol 5a-Androstan-3-one, 17beta-hydroxy- 5alpha,17beta-Hydroxyandrostan-3-one 5alpha-Androstan-3-one, 17beta-hydroxy- 5B-Androstan-3-on-17B-ol Androlone Androstan-3-one, 17-hydroxy-, (5alpha,17beta)- Cristerona MB cristeronamb Neodrol Protona Stanaprol Stanorone Testosterone, dihydro- 5α-Androstan-17β-ol-3-one,17β-Hydroxy-5α-androstan-3-one, 4,5α-Dihydrotestosterone, Androstanolone, Stanolone 5α-Dihydrotestosterone (DHT) Dihydrotestosterone (CIII) Stanolone/Androstanolone 5alpha-Androstan-17beta-ol-3-one 5alpha-Dihydrotestosterone DHT Stanolone(Androstanolone、DHT) ANDROSTANOLONE(RG) 5a-Androstan-17-ol-3-one-d6 (5S,8R,9R,10S,13S,14R,17S)-17-hydroxy-10,13-diMethyltetradecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one Androstan-3-one, 17-hydroxy-, (5q,17b)- Androstan-3-one,17-hydroxy-, (5a,17b)- 5α?DHT solution 5α-Dihydrotestosterone (DHT) solution 5α-Dihydrotestosterone solution 5ALPHA-DIHYDROTESTOSTOSTERONE 5A-DIHYDROTESTOSTERONE 5-ALPHA-ANDROSTANOLONE STANOLONE 4,5ALPHA-DIHYDROTESTOSTERONE (5S,8R,9S,10S,13S,14S,17S)-17-HYDROXY-10,13-DIMETHYL-HEXADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE ALLODIHYDROTESTOSTERONE 17BETA-HYDROXY-5ALPHA-ANDROSTAN-3-ONE 17b-hydroxy-5a-androstan-3-one 4,5a-Dihydrotestosterone Androstanolone/stanolone DIHYDROTESTOSTERONE CELL CULTURE*TESTED- -DEA SCHEDU STANOLONE (ANDROSTANOLONE) 17-HYDROXY-(5 A,17B)-A 5A-ANDROSTAN-17B-OL-3-ONE-DEASCHEDULE II I (5a,17b)-17-Hydroxyandrostan-3-one (5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one STANOLONE(5-ALPHA-ANDROSTANOLONE) 5A-ANDROSTAN-17B-OL-3-ONE, 98+% (5a,17)-17-Hydroxyandrostan-3-one 17β-Hydroxy-5α-androstan-3-one, 4,5α-Dihydrotestosterone, Androstanolone, Stanolone ANDROSTANOLONE VETRANAL, 250 MG