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Isobutylamine

CAS No.
78-81-9
Chemical Name:
Isobutylamine
Synonyms
IBA;MIBA;2-Methylpropanamine;sobutylaMine;2-METHYL-1-PROPANAMINE;2-Methyl-1-propylamine;C02787;nsc8028;Valamine;iso-C4H9NH2
CBNumber:
CB9211238
Molecular Formula:
C4H11N
Molecular Weight:
73.14
MDL Number:
MFCD00008146
MOL File:
78-81-9.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02

Isobutylamine Properties

Melting point -85 °C (lit.)
Boiling point 64-71 °C (lit.)
Density 0.736 g/mL at 25 °C (lit.)
vapor pressure 15.9kPa at 20℃
FEMA 4239 | ISOBUTYLAMINE
refractive index n20/D 1.397(lit.)
Flash point 15 °F
storage temp. Store below +30°C.
solubility 1000g/l
form Liquid
pka pK1:10.41(+1) (25°C)
color Clear colorless to slightly yellow
PH 12.2 (100g/l, H2O, 20℃)
Odor Strong ammoniacal.
Odor Threshold 0.0015ppm
explosive limit 2-9%(V)
Odor Type fishy
Water Solubility soluble
Merck 14,5132
JECFA Number 1583
BRN 385626
Dielectric constant 4.4(Ambient)
LogP -0.3 at 25℃
Substances Added to Food (formerly EAFUS) ISOBUTYLAMINE
CAS DataBase Reference 78-81-9(CAS DataBase Reference)
EWG's Food Scores 2
FDA UNII 1H60H4LOHZ
NIST Chemistry Reference 1-Propanamine, 2-methyl-(78-81-9)
EPA Substance Registry System Isobutylamine (78-81-9)
UNSPSC Code 12352116
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS05,GHS06
Signal word  Danger
Hazard statements  H225-H301-H314
Precautionary statements  P210-P233-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes  F,C
Risk Statements  11-22-35
Safety Statements  26-36/37/39-45
OEL STEL: 5.0 ppm; 15.0 mg/m3
RIDADR  UN 1214 3/PG 2
WGK Germany  1
RTECS  NP9900000
10-23
Autoignition Temperature 400°C
TSCA  Yes
HazardClass  3
PackingGroup  II
HS Code  29211990
Hazardous Substances Data 78-81-9(Hazardous Substances Data)
Toxicity LD50 (14 day) in male, female rats (mg/kg): 224.4, 231.8 orally (Cheever)
NFPA 704
3
3 0

Isobutylamine price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich I14150 Isobutylamine 99% 78-81-9 1l $90.1 2024-03-01 Buy
Sigma-Aldrich 8.41735 Isobutylamine for synthesis 78-81-9 250ML $48.7 2024-03-01 Buy
Sigma-Aldrich 8.41735 Isobutylamine for synthesis 78-81-9 1L $125 2024-03-01 Buy
TCI Chemical I0095 Isobutylamine >98.0%(GC) 78-81-9 25mL $31 2024-03-01 Buy
TCI Chemical I0095 Isobutylamine >98.0%(GC) 78-81-9 500mL $80 2024-03-01 Buy
Product number Packaging Price Buy
I14150 1l $90.1 Buy
8.41735 250ML $48.7 Buy
8.41735 1L $125 Buy
I0095 25mL $31 Buy
I0095 500mL $80 Buy

Isobutylamine Chemical Properties,Uses,Production

Chemical Properties

Isobutylamine is a flammable liquid, miscible with water, alcohol, and ether. Colorless to yellow liquid; fishy cheesy aroma.
Isobutylamine ball and stick model

Uses

Isobutylamine may be used in the synthesis of N-i-butyl-9(Z),12(Z),15(Z)-octadecatrienamide by reacting with trilinolenin. It can also react with tropolone to form a hydrogen-bonded complex, iso-butyl-ammonium 7-oxo-cyclo-hepta-1,3,5-trien-1-olate. Fullerene (C60) can undergo oxyamination with isobutylamine to form polyamines.

Production Methods

Isobutylamine is manufactured from isobutanol and ammonia or by the thermal decomposition of valine to isoleucine.

Aroma threshold values

High strength odor, fishy type; recommend smelling in a 0.10% solution or less.

General Description

Isobutylamine is a clear colorless liquid with a fishlike odor. Flash point 15°F. Less dense (6.1 lb / gal) than water. Vapors heavier than air. Produces toxic oxides of nitrogen during combustion.

Reactivity Profile

Isobutylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

Inhalation causes severe coughing and chest pain due to irritation of air passages; can cause lung edema. Compound is sympathomimetic and is also a cardiac depressant and convulsant; ingestion causes nausea and profuse salivation. Contact with eyes causes severe irritation and edema of the cornea. Contact with skin causes severe irritation.

Chemical Reactivity

Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Potential Exposure

Isobutylamine: Possible risk of forming tumors, suspected of causing genetic defects, suspected reprotoxic hazard, Primary irritant (w/o allergic reaction), (sec-isomer): Drug. n-Butylamine is used in pharmaceuticals; dyestuffs, rubber, chemicals, emulsifying agents; photography, desizing agents for textiles; pesticides, and synthetic agents. sec-Butylamine is used as a fungistate. tert-Butylamine is used as a chemical intermediate in the production of tert-Butylaminoethyl methacrylate (a lube oil additive); as an intermediate in the production of rubber and in rust preventatives and emulsion deterrents in petroleum products. It is used in the manufacture of several drugs.

Shipping

UN1125 n-Butylamine, Hazard Class: 3; Labels: 3—Flammable liquid, 8—Corrosive material. UN2014 Isobutylamine, Hazard Class: 3; Labels: 3—Flammable liquid, 8—Corrosive material

Incompatibilities

May form explosive mixture with air. May accumulate static electrical charges, and may causeignition of its vapors. n-Butylamine is a weak base; reacts with strong oxidizers and acids, causing fire and explosion hazard. Incompatible with organic anhydrides; isocyanates, vinyl acetate; acrylates, substituted allyls; alkylene oxides; epichlorohydrin, ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Attacks some metals in presence of moisture. The tert-isomer will attack some forms of plastics

Waste Disposal

Use a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner andscrubber. All federal, state, and local environmental regulations must be observed.

Global( 250)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+8617732866630 abby@chuanghaibio.com China 8773 58
Hebei Mujin Biotechnology Co.,Ltd
+86-13288715578 sales@hbmojin.com China 12648 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21622 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29855 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8615060885618 sales@amoychem.com China 6369 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5906 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49733 58
Richest Group Ltd
18017061086 oled@richest-group.com CHINA 5600 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58

View Lastest Price from Isobutylamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Isobutylamine pictures 2025-07-07 Isobutylamine
78-81-9
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mujin Biotechnology Co.,Ltd
Isobutylamine pictures 2025-06-24 Isobutylamine
78-81-9
US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
Isobutylamine pictures 2023-07-27 Isobutylamine
78-81-9
US $1.50 / g 1g 99.0% Min 100 Tons Shaanxi Didu New Materials Co. Ltd
  • Isobutylamine pictures
  • Isobutylamine
    78-81-9
  • US $0.00 / KG
  • 99%
  • Hebei Mujin Biotechnology Co.,Ltd
  • Isobutylamine pictures
  • Isobutylamine
    78-81-9
  • US $10.00 / KG
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd
  • Isobutylamine pictures
  • Isobutylamine
    78-81-9
  • US $1.50 / g
  • 99.0% Min
  • Shaanxi Didu New Materials Co. Ltd
nsc8028 Valamine ISOBUTYLAMINE 1-AMINO-2-METHYLPROPANE 2-METHYLPROPYLAMINE MONOISOBUTYLAMINE RARECHEM AL BW 0039 Isobuthylamine Isobutylamine,99% Isobutylamin Isobtuylamin 4-(Phenoxy)butanoyl chloride C02787 Isobutylamine,1-Amino-2-methylpropane IsobutylaMine 250ML 1-Aminoisobutane 1-amino-isobutane 1-Propanamine,2-methyl- 3-Methyl-2-propylamine i-Butylamine iso-C4H9NH2 2-Methyl-1-Aminopropane 2-methyl-1-propanamin IsobutylaMine, 99.5% 2-methyl-1-Propanamine 1-Aminoisobutane 1-amino-2-methylpropane isobutylamine iba Isobutylamine> ISOBUTYLAMINE FOR SYNTHESIS 250 ML Isobutylamine ISO 9001:2015 REACH CAS No.78-81-9 Isobutylamine IBA 2-Methylpropanamine 2-METHYL-1-PROPANAMINE MIBA sobutylaMine 2-Methyl-1-propylamine 78-81-9 78-81-2 CH32CHCH2NH2 78819 CH32CH2CH2NH2 Organic Building Blocks Nitrogen Compounds C2 to C6 Amines Building Blocks