ChemicalBook >> CAS DataBase List >>7-HYDROXYFLAVONE
7-HYDROXYFLAVONE
- CAS No.
- 6665-86-7
- Chemical Name:
- 7-HYDROXYFLAVONE
- Synonyms
- NSC 94258;4]cycloocta[1;7-HYDROXYFLAVONE;13-tetramethoxy-6;7-dimethylbenzo[3;HYDROXYFLAVONE, 7-;7-Hydroxyflavone>TIMTEC-BB SBB005921;7-Hydroxyflavone,98%;7-Hydroxy Flavone 99%
- CBNumber:
- CB9235797
- Molecular Formula:
- C15H10O3
- Molecular Weight:
- 238.24
- MDL Number:
- MFCD00006835
- MOL File:
- 6665-86-7.mol
- MSDS File:
- SDS
Last updated:2023-08-17 16:10:33
| Melting point | 245-247 °C (lit.) |
|---|---|
| Boiling point | 320.83°C (rough estimate) |
| Density | 1.340±0.06 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.5740 (estimate) |
| Water Solubility | Insoluble in water |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | powder to crystal |
| pka | 7.02±0.40(Predicted) |
| color | White to Light yellow |
| BRN | 194089 |
| LogP | 3.620 |
| CAS DataBase Reference | 6665-86-7(CAS DataBase Reference) |
| FDA UNII | ZE72458E4L |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29329990 | |||||||||
| NFPA 704 |
|
7-HYDROXYFLAVONE price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 41934 | 7-Hydroxyflavone analytical standard | 6665-86-7 | 50MG | $113 | 2024-03-01 | Buy |
| Sigma-Aldrich | H4530 | 7-Hydroxyflavone ≥98% | 6665-86-7 | 1g | $73.1 | 2023-06-20 | Buy |
| TCI Chemical | H0852 | 7-Hydroxyflavone >97.0%(T) | 6665-86-7 | 1g | $63 | 2024-03-01 | Buy |
| TCI Chemical | H0852 | 7-Hydroxyflavone >97.0%(T) | 6665-86-7 | 5g | $156 | 2024-03-01 | Buy |
| Alfa Aesar | A18538 | 7-Hydroxyflavone, 98% | 6665-86-7 | 1g | $48.65 | 2024-03-01 | Buy |
7-HYDROXYFLAVONE Chemical Properties,Uses,Production
Synthesis
Acetylation of resorcinol acetic acid yields 2,4-dihydroxyacetophenone, which is then subjected to benzoylation and transposition to obtain (2-hydroxy-4-benzoyloxy)benzoylacetophenone. 7-hydroxyflavone was obtained by further cyclization reaction in a mixture of acetic acid and hydrochloric acid at 103° C for 7 h.
Chemical Properties
off-white crystals
Uses
antifungal, analgesic
Uses
Reactant:
- Acting as a biologically valuable acceptor in O-glycosidation reactions
- Involved in synthesis of fully phosphorylated flavones for use as pancreatic cholesterol esterase inhibitors
- For O-methylation with di-Me carbonate
- Linked by a polymethylene chain for synthesis of α1-adrenoceptor antagonists
- Involved in Baylis-Hillman reactions
- Involved in phase-transfer catalyzed glucosylation for synthesis of glucosylated flavonoids
Definition
ChEBI: 7-hydroxyflavone is a hydroxyflavonoid in which the flavone nucleus is substituted at position 7 by a hydroxy group.
Synthesis Reference(s)
Tetrahedron Letters, 31, p. 6497, 1990 DOI: 10.1016/S0040-4039(00)97100-4
Biological Activity
7-Hydroxyflavone is a flavonoid isolated from M. indica with anti-inflammatory properties. It protects renal cells from nicotine (NIC)-induced cytotoxicity through the ERK/Nrf2/HO-1 pathway.
7-HYDROXYFLAVONE Preparation Products And Raw materials
Raw materials
Preparation Products
7-HYDROXYFLAVONE Suppliers
Global( 172)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Qyubiotech Co., Ltd. | +86-086-021-37596619 +8618019359838 | info@qyubiotech.com | China | 299 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12468 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3465 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
View Lastest Price from 7-HYDROXYFLAVONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-24 | 7-Hydroxyflavone
6665-86-7
|
US $0.00-0.00 / g | 10g | 98%+ | 10000kgs per Month | Shanghai Qyubiotech Co., Ltd. | |
 |
2020-03-13 | 7-HYDROXYFLAVONE
6665-86-7
|
US $1.00 / KG | 1KG | 98% HPLC | 10 tons | Career Henan Chemical Co |
-
- 7-Hydroxyflavone
6665-86-7
- US $0.00-0.00 / g
- 98%+
- Shanghai Qyubiotech Co., Ltd.
-
- 7-HYDROXYFLAVONE
6665-86-7
- US $1.00 / KG
- 98% HPLC
- Career Henan Chemical Co
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6665-86-7
Building Blocks
Benzopyrans
Flavonoids
Heterocyclic Building Blocks
Mono-substituted Flavones
Biochemistry
Flavonoids