ChemicalBook >> CAS DataBase List >>4-Hydroxybenzophenone
4-Hydroxybenzophenone
- CAS No.
- 1137-42-4
- Chemical Name:
- 4-Hydroxybenzophenone
- Synonyms
- POB;P-HYDROXYBENZOPHENONE;4-Hydroxydiphenylketone;NSC 1887;ENCL-001;benzoylphenol;Ospemifene INT;4-BENZOYLPHENOL;P-BENZOYLPHENOL;PARA-BENZOYLPHENOL
- CBNumber:
- CB9237221
- Molecular Formula:
- C13H10O2
- Molecular Weight:
- 198.22
- MDL Number:
- MFCD00002355
- MOL File:
- 1137-42-4.mol
- MSDS File:
- SDS
Last updated:2024-04-16 18:29:06
| Melting point | 132-135 °C(lit.) |
|---|---|
| Boiling point | 260-262°C 42mm |
| Density | 1.1184 (rough estimate) |
| vapor pressure | 0Pa at 20℃ |
| refractive index | 1.5954 (estimate) |
| Flash point | 260-262°C/24mm |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 8.14±0.13(Predicted) |
| form | Powder |
| color | White to beige to brown |
| Water Solubility | Insoluble in water. |
| BRN | 777776 |
| LogP | 1.6 at 35℃ |
| CAS DataBase Reference | 1137-42-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 04R2LWS0MS |
| NIST Chemistry Reference | Methanone, (4-hydroxyphenyl)phenyl-(1137-42-4) |
| EPA Substance Registry System | Methanone, (4-hydroxyphenyl)phenyl- (1137-42-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H373-H412 | |||||||||
| Precautionary statements | P260-P273-P314-P501 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37-24/25-36 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | PC4959775 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29145000 | |||||||||
| NFPA 704 |
|
4-Hydroxybenzophenone price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H20202 | 4-Hydroxybenzophenone 98% | 1137-42-4 | 25g | $67.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | H20202 | 4-Hydroxybenzophenone 98% | 1137-42-4 | 100g | $229 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.20661 | 4-Hydroxybenzophenone for synthesis | 1137-42-4 | 25g | $50.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.20661 | 4-Hydroxybenzophenone for synthesis | 1137-42-4 | 100g | $169 | 2024-03-01 | Buy |
| TCI Chemical | H0222 | 4-Hydroxybenzophenone >98.0%(GC)(T) | 1137-42-4 | 25g | $45 | 2024-03-01 | Buy |
4-Hydroxybenzophenone Chemical Properties,Uses,Production
Chemical Properties
white to beige fine crystalline powder
Uses
4-Hydroxybenzophenone is used in the field of organic synthesis. It is used as pharmaceutical intermediate of clomifene citrate.
Uses
Metabolite of benzophenone.
Preparation
Preparation by condensation of benzotrichloride,
? with phenol in the presence of aluminium chloride in carbon disulfide at 0° (90%) or in the presence of zinc oxide in a water bath;
? with p-bromophenol in 30% sodium hydroxide solution at 80–85° (81%). There is substitution of the bromine atom by the benzoyl group.
Definition
ChEBI: 4-Hydroxybenzophenone is a member of benzophenones.
Synthesis Reference(s)
Journal of the American Chemical Society, 77, p. 4674, 1955 DOI: 10.1021/ja01622a074
The Journal of Organic Chemistry, 19, p. 978, 1954 DOI: 10.1021/jo01371a016
Tetrahedron Letters, 31, p. 3943, 1990 DOI: 10.1016/S0040-4039(00)97513-0
Flammability and Explosibility
Not classified
Purification Methods
Dissolve p-benzoylphenol in hot EtOH (charcoal), filter and cool. Alternatively crystallise it once from EtOH/H2O and twice from *benzene [Grunwald J Am Chem Soc 73 4934 1951, Dryland & Sheppard J Chem Soc Perkin Trans 1 125 1986]. [Beilstein 8 IV 1263.]
4-Hydroxybenzophenone Preparation Products And Raw materials
Raw materials
Aluminum chloride
Phenyl benzoate
Imidodicarbonic acid, 2-benzoyl-, 1,3-bis(1,1-dimethylethyl) ester
4-BENZYLOXYBENZOPHENONE
4-Methoxybenzophenone
1of3
Preparation Products
Global( 576)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 20000 | 58 |
| Junwee Chemical co., Ltd. | +86-571-85808636 +86-13958122542 | sales@junweechem.com | China | 821 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12457 | 58 |
| Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 436 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 1175 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
View Lastest Price from 4-Hydroxybenzophenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-18 | 4-Hydroxybenzophenone
1137-42-4
|
US $50.00 / kg | 1kg | 99.10% | 5000kg | Ouhuang Engineering Materials (Hubei) Co., Ltd | |
 |
2024-04-02 | 4-Hydroxybenzophenone
1137-42-4
|
US $0.00-0.00 / kg | 1kg | 99% | 50000kg | Hebei Yibangte Import and Export Co. , Ltd. | |
 |
2024-01-08 | 4-Hydroxybenzophenone
1137-42-4
|
US $65.00-30.00 / kg | 1kg | 99.5% | 500tons | Wuhan Boyuan Import & Export Co., LTD |
-
- 4-Hydroxybenzophenone
1137-42-4
- US $50.00 / kg
- 99.10%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
-
- 4-Hydroxybenzophenone
1137-42-4
- US $0.00-0.00 / kg
- 99%
- Hebei Yibangte Import and Export Co. , Ltd.
-
- 4-Hydroxybenzophenone
1137-42-4
- US $65.00-30.00 / kg
- 99.5%
- Wuhan Boyuan Import & Export Co., LTD
1137-42-4(4-Hydroxybenzophenone)Related Search:
(4-hydroxyphenyl)phenyl-methanon
4-hydroxy-benzophenon
4-Hydroxyphenylphenylketone
Benzophenone, 4-hydroxy-
benzoylphenol
P-BENZOYLPHENOL
4-BENZOYLPHENOL
4-HYDROXYBENZOPHENONE
(4-HYDROXY-PHENYL)-PHENYL-METHANONE
HYDROXYBENZOPHENONE-4
4-Hydroxybenzophenone, 99+%
4-Hydroxybenzophenone, pract.
Methanone, (4-hydroxyphenyl)phenyl-
4-HYDROXYBENZOPHENONE=99.0%
4-hydroxybenzophenone (intermediate of toremifene citrate)
PARA-BENZOYLPHENOL
(4-hydroxy)(phenyl)methanone
4-Hydroxybenzophenone, 98+%
4-Hydroxybenzophenone, 99+% 25GR
1-(4-Hydroxyphenyl)-1-phenylMethanone
NSC 1887
p-Hydroxybenzophenonfe
(4-Hydroxyphenyl)(phenyl)methanone, 4-Benzoylphenol
4-Hydroxybenzophenone≥ 99% (HPLC)
4-Hydroxybenzophene
Photoinitiator-4HBP
1-benzoyl-4-hydroxy-benzene
4-Hydroxybenzophenone, (4-Hydroxyphenyl)phenyl-methanone
ENCL-001
4-Hydroxybenzophenone, 99%, for synthesis
4-Hydroxybenzophenone>
4-HYDROXYBENZOPHENONE FOR SYNTHESIS
4',2,4-trimethoxy benzophenone
Benzophenone 4-Hydroxybenzophenone organic photoinitiators
4-Hydroxydiphenylketone
POB
P-HYDROXYBENZOPHENONE
Ospemifene INT
4-hydroxy
benzophenone
(PHBP)
1137-42-4
1137-72-4
HOC6H4COC6H5
Building Blocks
Organic Building Blocks
Ketones
KETONE
Carbonyl Compounds
C7 to C8
Aromatics, Metabolites & Impurities
Organic Photoinitiators
Benzophenone
Polymerization Initiators
FINE Chemical & INTERMEDIATES
Aromatic Benzophenones & Derivatives (substituted)
Aromatics
Metabolites & Impurities
bc0001
1137-42-4