ChemicalBook >> CAS DataBase List >>2,3,4-Trimethoxybenzaldehyde

2,3,4-Trimethoxybenzaldehyde

CAS No.
2103-57-3
Chemical Name:
2,3,4-Trimethoxybenzaldehyde
Synonyms
TriMetazidine EP IMpurity-C;Benzaldehyde, 2,3,4-trimethoxy-;2,3,4-TMB;AKOS BBS-00003174;2,3,4-TrimethoxybenzaL;Trimetazidine Impurity C;4-TriMethoxybenzaldehyde;trimetazidine impurity1139;2,3,4-Trimetoxybenzaldehyde;Trimetazidine intermediate
CBNumber:
CB9260504
Molecular Formula:
C10H12O4
Molecular Weight:
196.2
MDL Number:
MFCD00003310
MOL File:
2103-57-3.mol
MSDS File:
SDS
Last updated:2024-03-20 19:26:33

2,3,4-Trimethoxybenzaldehyde Properties

Melting point 38-40 °C(lit.)
Boiling point 168-170 °C12 mm Hg(lit.)
Density 1.2166 (rough estimate)
refractive index n20/D 1.5547(lit.)
Flash point >230 °F
storage temp. Inert atmosphere,2-8°C
solubility methanol: 0.1 g/mL, clear
form Crystals or Crystalline Powder
color White to light yellow
Sensitive Air Sensitive
BRN 981091
InChI InChI=1S/C10H12O4/c1-12-8-5-4-7(6-11)9(13-2)10(8)14-3/h4-6H,1-3H3
InChIKey UCTUXUGXIFRVGX-UHFFFAOYSA-N
SMILES C(=O)C1=CC=C(OC)C(OC)=C1OC
CAS DataBase Reference 2103-57-3(CAS DataBase Reference)
FDA UNII 7ZY3UK34C4
NIST Chemistry Reference Benzaldehyde, 2,3,4-trimethoxy-(2103-57-3)
EPA Substance Registry System Benzaldehyde, 2,3,4-trimethoxy- (2103-57-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi,C
Risk Statements  36/37/38-34
Safety Statements  22-24/25-45-36/37/39-27-26
WGK Germany  3
Hazard Note  Irritant
TSCA  Yes
HS Code  29124900
NFPA 704
1
0 0

2,3,4-Trimethoxybenzaldehyde price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 152099 2,3,4-Trimethoxybenzaldehyde 99% 2103-57-3 10g $33.3 2024-03-01 Buy
Sigma-Aldrich 152099 2,3,4-Trimethoxybenzaldehyde 99% 2103-57-3 50g $108 2024-03-01 Buy
TCI Chemical T1101 2,3,4-Trimethoxybenzaldehyde >98.0%(GC) 2103-57-3 25g $66 2024-03-01 Buy
Alfa Aesar A10609 2,3,4-Trimethoxybenzaldehyde, 98+% 2103-57-3 10g $28.65 2024-03-01 Buy
Alfa Aesar A10609 2,3,4-Trimethoxybenzaldehyde, 98+% 2103-57-3 50g $102.65 2024-03-01 Buy
Product number Packaging Price Buy
152099 10g $33.3 Buy
152099 50g $108 Buy
T1101 25g $66 Buy
A10609 10g $28.65 Buy
A10609 50g $102.65 Buy

2,3,4-Trimethoxybenzaldehyde Chemical Properties,Uses,Production

Description

2,3,4-Trimethoxybenzaldehyde is a white crystalline powder, and the chemical formula is C 10H 12O 4; the molecular weight is 196.2; the fusing point is 38-40 degrees, and is a kind of important medicine intermediate; it is mainly used in new type drug Ca2+ Synthesizing of channel blocker. The alternative cerebral arteries that are used for this medicine reduce the headache incidence, mainly for the preparation of the intermediate of trimetazidine.

Synthesis

A coking gallic acid is utilized as a raw material, and dimethyl sulfate is utilized as an alkylate reagent; under the condition of the existence of sodium hydroxide, methylation is performed through an O-alkylation reaction to obtain an intermediate 1, 2, 3-trimethoxybenzene. After that, the 1,2, 3-trimethoxybenzene and a Vilsmeier-Haack reagent are subjected to a formylation reaction to get the 2,3,4-Trimethoxybenzaldehyde.

Chemical Properties

white to light yellow crystals or cryst. powder

Uses

2,3,4-Trimethoxybenzaldehyde was used to study the effects of 2,3,4-trimethoxybenzaldehyde on tubulin-dependent GTP hydrolysis.

Uses

2,3,4-Trimethoxybenzaldehyde is a trimethoxylated aromatic aldehyde. 2,3,4-Trimethoxybenzaldehyde is an Impurity of the anti-anginal drug Trimetazidine (T795610).

50-00-0
634-36-6
2103-57-3
Synthesis of 2,3,4-Trimethoxybenzaldehyde from Formaldehyde and 1,2,3-Trimethoxybenzene
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View Lastest Price from 2,3,4-Trimethoxybenzaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,3,4-Trimethoxybenzaldehyde pictures 2024-04-25 2,3,4-Trimethoxybenzaldehyde
2103-57-3
US $12.00 / kg 1kg 99% 200mt Jinan Finer Chemical Co., Ltd
2,3,4-Trimethoxybenzaldehyde pictures 2024-04-24 2,3,4-Trimethoxybenzaldehyde
2103-57-3
US $86.00-76.00 / kg 10kg 99.99% 100Tons Hebei Dangtong Import and export Co LTD
2,3,4-Trimethoxybenzaldehyde pictures 2024-04-22 2,3,4-Trimethoxybenzaldehyde
2103-57-3
US $30.00 / kg 1kg 99% 2000kg hebei hongtan Biotechnology Co., Ltd
2,3,4-trimethoxy-benzaldehyd 2,3,4-TRIMETHOXYBENZALDEHYDE FOR SYNTHES Trimetazidine Impurity C 2,3,4-TriMethoxybenzaldehyde, 97+% 2,3,4 TRIMETHOXYBENZYLALDEHYDE 2,3,4-TRIMETHOXYBENZALDEHYDE 2,3,4-TMB 2,3,4-Trimethoxybenzaldehyde, 99+% 2,3,4-trimethoxybenzaldehyde (intermediate of trimetazidine.) 2,3,4-Trimetoxybenzaldehyde 4.2,3,4-trimethoxybenzaldehyde 2,3,4-TRIMETHOXYBENZALDEHYDE, 98+% 4-TriMethoxybenzaldehyde 2,3,4-TriMethoxybenzaldehyde, 99% 10GR AKOS BBS-00003174 2,3,4-TrimethoxybenzaL 2,3,4-Trimedhoxy Benzaldehyde Trimetazidine Impurity 3(Trimetazidine EP Impurity C) 2,3,4-Trimethoxybenzaidehyde 2,3,4-Trimethoxybenzaldehyde ISO 9001:2015 REACH trimetazidine impurity1139 TriMetazidine EP IMpurity-C Benzaldehyde, 2,3,4-trimethoxy- 2,3,4-Trimethoxybenzaldehyde (Trimetazidine Hydrochloride Impurity) Trimetazidine intermediate Trimetazidine Dihydrochloride EP Impurity C 2103-57-3 2103-57-31 Organic Building Blocks ALDEHYDE Aldehydes Building Blocks C10 to C21 Carbonyl Compounds Aromatics, Impurities, Intermediates BUILDING BLOCKS Benzaldehyde API intermediates (intermediate of trimetazidine.) Aldehydes C10 to C21 Carbonyl Compounds Aromatic Aldehydes & Derivatives (substituted) bc0001 2103-57-3