ChemicalBook >> CAS DataBase List >>6-O-Benzylguanine

6-O-Benzylguanine

CAS No.
19916-73-5
Chemical Name:
6-O-Benzylguanine
Synonyms
6-benzylguanine;O6-BENZYLGUANINE;O6-Benzylguanine ,98%;6-(benzyloxy)-7H-purin-2-aMine;O6-BenzyL;NSC 637037;6-O-BENZYLGUANINE;6-BENZYLOXY GUANINE;6-oxo -benzylguanine;4 6-Benzyloxyguanine
CBNumber:
CB9263934
Molecular Formula:
C12H11N5O
Molecular Weight:
241.25
MDL Number:
MFCD00269931
MOL File:
19916-73-5.mol
MSDS File:
SDS
Last updated:2024-03-16 07:03:48

6-O-Benzylguanine Properties

Melting point 193(dec.)
Boiling point 459.3±55.0 °C(Predicted)
Density 1.48±0.1 g/cm3(Predicted)
storage temp. room temp
solubility methanol: 20 mg/mL
form solid
pka 7.47±0.20(Predicted)
color Off-White to Light Yellow
CAS DataBase Reference 19916-73-5(CAS DataBase Reference)
NCI Dictionary of Cancer Terms O(6)-benzylguanine
FDA UNII 01KC87F8FE
NCI Drug Dictionary O6-benzylguanine

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
Hazard Note  Irritant
HS Code  29339900
NFPA 704
1
2 0

6-O-Benzylguanine price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B2292 O6-Benzylguanine ≥98% (TLC), solid 19916-73-5 50mg $107 2024-03-01 Buy
Alfa Aesar H60274 O6-Benzylguanine, 98% 19916-73-5 250mg $47.65 2024-03-01 Buy
Cayman Chemical 16332 O6-Benzylguanine ≥98% 19916-73-5 10mg $32 2024-03-01 Buy
Cayman Chemical 16332 O6-Benzylguanine ≥98% 19916-73-5 1g $699 2024-03-01 Buy
Cayman Chemical 16332 O6-Benzylguanine ≥98% 19916-73-5 50mg $56 2024-03-01 Buy
Product number Packaging Price Buy
B2292 50mg $107 Buy
H60274 250mg $47.65 Buy
16332 10mg $32 Buy
16332 1g $699 Buy
16332 50mg $56 Buy

6-O-Benzylguanine Chemical Properties,Uses,Production

Chemical Properties

Light Yellow Solid

Uses

O6-Benzylguanine is an effective substrate and efficient inactivator of DNA alkyltransferase. O6-Benzylguanine is an inhibitor of MGMT. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Uses

An irreversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. Assists in the protection against carcinogenic and therapeutic alkylating agents.

Biochem/physiol Actions

O6-Benzylguanine (O6BG) inhibits methylguanine methyltransferase (MGMT) by blocking the active site through benzyl group transfer. The use of O6BG with bis-chloroethylnitrosourea (BCNU) or carmustine is effective in treating solid tumors including lymphomas, melanomas and sarcoma.

Global( 397)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+86-13288715578 +86-13231137666 sales@hbmojin.com China 12409 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5960 58
Henan Fengda Chemical Co., Ltd
+8613613820652 info@fdachem.com China 4685 58
airuikechemical co., ltd.
+undefined86-15315557071 15315557071@163.com China 137 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 14770 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29919 58
Zhejiang ZETian Fine Chemicals Co. LTD
18957127338 stella@zetchem.com China 2141 58
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 8136 58

View Lastest Price from 6-O-Benzylguanine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
O6-Benzylguanine pictures 2024-03-16 O6-Benzylguanine
19916-73-5
US $0.00-0.00 / g 1g 99.9% 20 tons airuikechemical co., ltd.
O6-Benzylguanine pictures 2024-01-11 O6-Benzylguanine
19916-73-5
US $122.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
6-O-Benzylguanine pictures 2023-10-23 6-O-Benzylguanine
19916-73-5
US $20.00-1.00 / kg 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
  • O6-Benzylguanine pictures
  • O6-Benzylguanine
    19916-73-5
  • US $122.00-1.00 / KG
  • 99%
  • Henan Fengda Chemical Co., Ltd

6-O-Benzylguanine Spectrum

O(sup 6)benzylguanidine 2-Amino-6-(benzyloxy)-9H-purine 6-(Benzyloxy)-1H-purin-2-amine 6-(PhenylMethoxy)-9H-purin-2-aMine NSC 637037 6-oxo -benzylguanine 6-O-Benzylguanine(O6BG) 9H-Purin-2-amine,6-(phenylmethoxy)- 6-phenylmethoxy-7H-purin-2-amine 2-Amino-6-(benzyloxy)purine 2-amino-6-(phenylmethoxy)-9h-purine 6-O-BENZYLGUANINE 6-BENZYLOXY-9H-PURIN-2-AMINE 6-BENZYLOXY GUANINE 4 6-Benzyloxyguanine 6-BENZYLOXY GUANINE2-AMINO-6-BENZYLOXYPURINE Ganciclovir Impurity 12 O6-BenzyL 2-((2-acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)propane-1,3-diyl dibenzoate "2-Amino-6-(benzyloxy)purine, 2-Amino-6-(phenylmethoxy)-9H-purine" O6-Benzylguanine ,98% 6-(benzyloxy)-7H-purin-2-aMine 6-benzylguanine O6-BENZYLGUANINE 19916-73-5 9916-73-5 Apoptosis and Cell Cycle DNA Repair Regulators DNA metabolism BioChemical Cell Signaling and Neuroscience Cell Biology Alkylguanine-DNA alkyltransferase, mammalian DNA repair proteinApoptosis and Cell Cycle DNA Repair Regulators A to DNA metabolism Enzyme Inhibitors by Enzyme Nucleotides and Nucleosides Bases & Related Reagents Nucleotides