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Quetiapine fumarate

Antipsychotics Chemical properties Uses

CAS No.111974-72-2
Chemical Name:Quetiapine fumarate
Molecular Formula:C46H54N6O8S2
Formula Weight:883.09
MOL File:111974-72-2.mol
Quetiapine fumarate Property
Melting point : 174-176°C
storage temp. : -20°C Freezer
CAS DataBase Reference: 111974-72-2(CAS DataBase Reference)
Hazard Codes : Xn,N,T,F
Risk Statements : 22-50/53-52/53-39/23/24/25-23/24/25-11
Safety Statements : 60-61-45-36/37-16

Quetiapine fumarate Chemical Properties,Usage,Production

Quetiapine fumarate is an antipsychotic, successfully developed by the AstraZeneca United States, it interacts with a variety of neurotransmitter receptors, in the brain, it displays high degree affinity for serotonin (5-HT2) receptor, and it is greater than dopamine D1 and D2 dopamine receptor affinity in the brain. Quetiapine also has high affinity for histamine H1 receptor and adrenergic α1 receptors, and low affinity for α2 receptors, but it basically displays no affinity for cholinergic muscarinic receptors or benzodiazepine receptors . It shows positive results in antipsychotic activity assays such as conditioned avoidance reflex . In clinical, it is mainly used in treatment for adults with severe depression, acute manic episodes of bipolar disorder and schizophrenia of different types . It is not only effective for the positive symptoms of schizophrenia, but also having a certain effect for negative symptoms . It can also alleviate affective symptoms associated with schizophrenia, such as depression, anxiety symptoms and cognitive deficits.
The above information is edited by the chemicalbook of Tian Ye.
Chemical properties
White crystalline powder.
A non-classical antipsychotics.
Chemical Properties
White Crystalline Solid
Used as an antipsychotic. Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties
antihypertensive adrenergic receptor blocking agent with selective alpha1- and nonselective beta-adrenergic receptor blocking actions in a single substance.
Quetiapine fumarate Preparation Products And Raw materials
Raw materials
Preparation Products
Quetiapine fumarate Suppliers      Global( 228)Suppliers     
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259 CHINA 3226 55
Wuhan Dahua Weiye Pharmaceutical Chemical Co., Ltd. 027-59262863 13277907145 QQ 3091977954 China 1976 50
Shanghai JONLN Reagent Co., Ltd. 021-61552785 China 10344 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833; China 96832 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037 China 15950 69
Chembest Research Laboratories Limited +86(0)21-20908456
+86(0); China 6015 61
TCI (Shanghai) Development Co., Ltd. 800-988-0390 China 22833 81
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078,021-50426030
86-021-50426522, China 10094 60
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 United States 9946 62
Chemfun Medical Technology(Shanghai) Co., Ltd. 021-67220633 & 021-37212706 China 21909 59
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SEROQUEL QUETIAPINE FUMARATE QUETIAPINE HEMIFUMARATE 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate 111974-72-2 DIBENZOTHIAZEPINOHONEP ICI-204636 QUETIAPINE FUMARATE, 99+% Quetiapine Fumarate main intermediates C42H50N6O4S2C4H4O4 2C21H25N3O2SC4H4O4 Seroquel, ICI-204636, Dibenzothiazepinohonep QUETIAPINE HEMIGUMARTE C21H25N3O2S12C4H4O4 Active Pharmaceutical Ingredients C46H54N6O8S2 Antipsychotic Intermediates & Fine Chemicals Pharmaceuticals Quetiapine Quetiapine·0.5fumaric acid 2-[2-(4-{2-thia-9-azatricyclo[^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-10-yl}piperazin-1-yl)ethoxy]ethan-1-ol Quetiapine fuMarate(Seroquel) 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol Bis[(2E)-2-Butenedioate] Quetiapine FuMarate API Quetiapine heMifuMarate salt QUETIAPINE HEMIFUMERATE API Quetiapine fuMarate USP 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-ethanol,(2E)-2-butenedioate (2:1) Quetiapine fumarate solution Quetiapine for system suitability Pharmaceutical raw materials bulk drug material QuetiapineFamarate Inhibitors
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