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Quetiapine fumarate

Antipsychotics Chemical properties Uses

CAS No.111974-72-2
Chemical Name:Quetiapine fumarate
Molecular Formula:C46H54N6O8S2
Formula Weight:883.09
MOL File:111974-72-2.mol
Quetiapine fumarate Property
Melting point : 174-176°C
storage temp. : -20°C Freezer
CAS DataBase Reference: 111974-72-2(CAS DataBase Reference)
Hazard Codes : Xn,N,T,F
Risk Statements : 22-50/53-52/53-39/23/24/25-23/24/25-11
Safety Statements : 60-61-45-36/37-16

Quetiapine fumarate Chemical Properties,Usage,Production

Quetiapine fumarate is an antipsychotic, successfully developed by the AstraZeneca United States, it interacts with a variety of neurotransmitter receptors, in the brain, it displays high degree affinity for serotonin (5-HT2) receptor, and it is greater than dopamine D1 and D2 dopamine receptor affinity in the brain. Quetiapine also has high affinity for histamine H1 receptor and adrenergic α1 receptors, and low affinity for α2 receptors, but it basically displays no affinity for cholinergic muscarinic receptors or benzodiazepine receptors . It shows positive results in antipsychotic activity assays such as conditioned avoidance reflex . In clinical, it is mainly used in treatment for adults with severe depression, acute manic episodes of bipolar disorder and schizophrenia of different types . It is not only effective for the positive symptoms of schizophrenia, but also having a certain effect for negative symptoms . It can also alleviate affective symptoms associated with schizophrenia, such as depression, anxiety symptoms and cognitive deficits.
The above information is edited by the chemicalbook of Tian Ye.
Chemical properties
White crystalline powder.
A non-classical antipsychotics.
Chemical Properties
White Crystalline Solid
Used as an antipsychotic. Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties
antihypertensive adrenergic receptor blocking agent with selective alpha1- and nonselective beta-adrenergic receptor blocking actions in a single substance.
Quetiapine fumarate Preparation Products And Raw materials
Raw materials
Preparation Products
Quetiapine fumarate Suppliers      Global( 224)Suppliers     
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111974-72-2(Quetiapine fumarate)Related Search:
Sodium 4-aminosalicylate dihydrate Risperidone 1,9-Pyrazoloanthrone ABT 737 Fumaric acid 1-[2-(2-hydroxyethoxy)ethyl]piperazine 2HCL (intermediate of quetiapine fumarate) 1-hydroxyethoxyethylpiperazine (intermediate of quetiapine fumarate) 1-[2-(2-hydroxyethoxy)ethyl]piperazine (intermediate of quetiapine fumarate) 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-ethanol N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Quetiapine fumarate
SEROQUEL QUETIAPINE FUMARATE QUETIAPINE HEMIFUMARATE 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate 111974-72-2 DIBENZOTHIAZEPINOHONEP ICI-204636 QUETIAPINE FUMARATE, 99+% Quetiapine Fumarate main intermediates C42H50N6O4S2C4H4O4 2C21H25N3O2SC4H4O4 Seroquel, ICI-204636, Dibenzothiazepinohonep QUETIAPINE HEMIGUMARTE C21H25N3O2S12C4H4O4 Active Pharmaceutical Ingredients C46H54N6O8S2 Antipsychotic Intermediates & Fine Chemicals Pharmaceuticals Quetiapine Quetiapine·0.5fumaric acid 2-[2-(4-{2-thia-9-azatricyclo[^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-10-yl}piperazin-1-yl)ethoxy]ethan-1-ol Quetiapine fuMarate(Seroquel) 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol Bis[(2E)-2-Butenedioate] Quetiapine FuMarate API Quetiapine heMifuMarate salt QUETIAPINE HEMIFUMERATE API Quetiapine fuMarate USP 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-ethanol,(2E)-2-butenedioate (2:1) Quetiapine fumarate solution Quetiapine for system suitability Pharmaceutical raw materials bulk drug material QuetiapineFamarate Inhibitors
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