Mal-PEG1-acid
- CAS No.
- 760952-64-5
- Chemical Name:
- Mal-PEG1-acid
- Synonyms
- Mal-PEG1-acid;Mal-PEG1-CH2CH2COOH;3-[2-(2,5-dioxopyrrol-1-yl)ethoxy]propanoic acid;3-[2-(2,5-Dioxo-2,5-dihydro-1-pyrrolyl)ethoxy]propanoic Acid;3-[2-(2,5-Dioxo-2,5-dihydro-1h-pyrrol-1-yl)ethoxy]propanoic acid;Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-;Mal-PEG1-CH2CH2COOH/Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-
- CBNumber:
- CB93062525
- Molecular Formula:
- C9H11NO5
- Molecular Weight:
- 213.19
- MDL Number:
- MFCD24497443
- MOL File:
- 760952-64-5.mol
Mal-PEG1-acid price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M158213 | Mal-PEG1-acid | 760952-64-5 | 50mg | $330 | 2021-12-16 | Buy |
| ChemScene | CS-0108926 | Mal-PEG1-acid | 760952-64-5 | 250mg | $520 | 2021-12-16 | Buy |
| BroadPharm | BP-21859 | Mal-PEG1-acid 98% | 760952-64-5 | 250mg | $575 | 2021-12-16 | Buy |
| Apolloscientific | BIPG1491 | Mal-PEG1-acid | 760952-64-5 | 100mg | $669 | 2021-12-16 | Buy |
| ChemScene | CS-0108926 | Mal-PEG1-acid | 760952-64-5 | 100mg | $300 | 2021-12-16 | Buy |
Mal-PEG1-acid Chemical Properties,Uses,Production
Description
Mal-PEG1-acid is a PEG linker containing a maleimide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Biological Activity
Mal-PEG1-acid is a non-cleavable ADC linker containing 1 unit PEG, which can be used to synthesize antibody drug conjugates (ADC),it is a PROTAC linker belonging to the PEG class, which can be used to synthesize PROTAC molecules.
in vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
target
| PEGs
| Non-cleavable
|
Mal-PEG1-acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Wuhan Brin Technology Co., Ltd. | 3456065315 13260619011 | 3456065315@qq.com | China | 1730 | 58 |
| Hygeia (Chengdu) pharmaceutical technique Co., Ltd | 028-84502008 13568869383 | sales@hygeiapharm.com | China | 294 | 55 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6357 | 58 |
View Lastest Price from Mal-PEG1-acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-27 | Mal-PEG1-acid
760952-64-5
|
US $0.00 / g | 5g | >98.00% | 5g | Xian confluore Biological Technology Co., Ltd. |
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- Mal-PEG1-acid
760952-64-5
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.