2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER
- CAS No.
- 118-57-0
- Chemical Name:
- 2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER
- Synonyms
- SALOPHEN;Asalphen;Phenestal;Cetosalol;Phenetsal;acetaminosalol;p-Acetamidophenyl salicylate;4-acetamidophenyl salicylate;4-Acetaminophenyl salicylate;ACETYL-P-AMINOPHENYLSALICYLATE
- CBNumber:
- CB9322358
- Molecular Formula:
- C15H13NO4
- Molecular Weight:
- 271.27
- MDL Number:
- MFCD00020033
- MOL File:
- 118-57-0.mol
- MSDS File:
- SDS
| Melting point | 187° |
|---|---|
| Stability | Stable. Incompatible with strong oxidizing agents. |
| LogP | 2.562 (est) |
| EWG's Food Scores | 1 |
| FDA UNII | O3J7H54KMD |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H317-H319 |
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P280-P305+P351+P338-P337+P313P |
2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER Chemical Properties,Uses,Production
Chemical Properties
solid
Originator
Acetaminosal ,ZYF Pharm Chemical
Uses
Analgesic; antipyretic.
Definition
ChEBI: Acetaminosalol is a carbonyl compound.
Manufacturing Process
2 Methods of producing of acetyl salicylic acid ester of N-acetyl-paminophenol:
1. 65.0 g of N-acetyl-p-aminophenol were slurried with 400 ml of water and
cooled to 10°C. 125 ml of 20% sodium hydroxide were slowly added to the
mixture with stirring, the temperature being maintained 10°-15°C. To the
solution obtained, 75.0 g of acetyl salicylic chloride were added with vigorous
stirring over a period of 0.5 h, the solution being maintained at a temperature of about 10°C. Towards the end of the reaction the pH was checked and
adjusted to greater than 10 by the addition of a small amount of 20% sodium
hydroxide. After all the acid chloride had been added, vigorous stirring was
continued for 0.5 h during which time the crude product separated out. The
acetyl salicylic acid ester of N-acetyl-p-aminophenol was filtered off, washed
thoroughly with water and recrystallised from ethanol.
2. 65.0 g of sodium N-acetyl-p-aminophenol were slurried with 500.0 g of dry
benzene and 80.0 g of acetyl salicylic chloride added. The mixture was heated
under reflux for 4 h and filtered hot. The excess benzene was removed under
vacuum and the crude acetyl salicylic acid ester of N-acetyl-p-aminophenol
crystallized from ethanol.
brand name
Acephen (G & W); Infants’ Feverall (Actavis); Injectapap (Ortho-McNeil); Neopap (Polymedica); Tylenol (McNeil).
Therapeutic Function
Analgesic, Antineuralgic, Antirheumatic, Antipyretic
2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29322 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| SynAsst Chemical. | 021-60343070 | China | 12742 | 55 | |
| Shandong Wadesen Biotechnology Co. LTD | 0531-88723173 18596073690 | 1047208234@qq.com | China | 3418 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 029-81124267 15229202216 | 1073@dideu.com | China | 10011 | 58 |
| Supplier | Advantage |
|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 58 |
| Dideu Industries Group Limited | 58 |
| Alfa Chemistry | 58 |
| SynAsst Chemical. | 55 |
| Shandong Wadesen Biotechnology Co. LTD | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 58 |
View Lastest Price from 2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-06-11 | 2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER USP/EP/BP
118-57-0
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
-
- 2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER USP/EP/BP
118-57-0
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited