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Dropropizine

Dropropizine structure

CAS No.: 17692-31-8

Chemical Name:: Dropropizine

Synonyms: ribex;katril;larylin;catabex;UCB-196;ditustat;tussilex;gevotuss;UCB-1967;dopropizin

CBNumber:: CB9328471

Molecular Formula:: C13H20N2O2

Molecular Weight:: 236.31

MDL Number:: MFCD00079124

MOL File:: 17692-31-8.mol

MSDS File:: SDS

Last updated:2023-06-08 09:03:02

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Dropropizine Properties

Melting point	105° (Morren); mp 108° (Bourdais)
Boiling point	205 °C(Press: 1 Torr)
Density	1.168±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Sparingly), Methanol (Slightly)
pka	14.21±0.20(Predicted)
color	White to Off-White
CAS DataBase Reference	17692-31-8(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	U0K8WHL37U
ATC code	R05DB19

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P280-P305+P351+P338

Hazard Codes

Risk Statements

Safety Statements

WGK Germany

RTECS

TZ1074800

Toxicity

LD50 in rats (mg/kg): 200 i.v., 750 orally (Morren)

NFPA 704

	0
1		0

Dropropizine price More Price(16)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	D4285	(±)-Dropropizine analytical standard, for drug analysis	17692-31-8	5g	$55.7	2022-05-15	Buy
TRC	D681495	racDropropizine	17692-31-8	1g	$120	2021-12-16	Buy
AK Scientific	H962	Dropropizine	17692-31-8	5g	$47	2021-12-16	Buy
AK Scientific	H962	Dropropizine	17692-31-8	100g	$561	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0014296	DROPROPIZINE 95.00%	17692-31-8	1G	$716.1	2021-12-16	Buy

Product number	Packaging	Price	Buy
D4285	5g	$55.7	Buy
D681495	1g	$120	Buy
H962	5g	$47	Buy
H962	100g	$561	Buy
CHM0014296	1G	$716.1	Buy

Dropropizine Chemical Properties,Uses,Production

Originator

Ribex,Formenti

Uses

antitussive

Uses

Dropropizine is a cough suppressant and central sedative therapeutic agent.

Definition

ChEBI: 3-(4-phenyl-1-piperazinyl)propane-1,2-diol is a member of piperazines.

Manufacturing Process

34 g 1,2-epoxy-3-hydroxypropane (glycide) in 50 ml of water were added to 64.8 g 1-phenylpiperazine in 80 ml of ethanol at the temperature not higher 50°C. The mixture was stood at night, then it was evaporated to dryness in vacuum and the stark product was recrystallized from 100 ml of acetone to give 60 g 1-phenyl-4-(2,3-dihydroxypropyl)piperazine (dropropizine) MP 105°C; BP 205°C/1 mm Hg.

Therapeutic Function

Antitussive

Dropropizine Preparation Products And Raw materials

Raw materials

p-Toluenesulfonic acid 1-Phenylpiperazine Ethanol Acetone Sodium sulfate

Toluene 2,2-Dimethyl-1,3-dioxolane-4-methanol Sodium borohydride Chloroform Diethanolamine

Tosyl chloride Zinc dichloride Hydrochloric acid D-Mannitol Methanol

Sodium periodate 3-Chloro-1,2-propanediol Pyridine Phenylpiperazine Glycidol

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Preparation Products

Dropropizine Suppliers

Global( 178)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	2995	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81148696 +8615536356810	1047@dideu.com	China	3679	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58

Supplier	Advantage
career henan chemical co	58
Xi'an Kono chem co., Ltd.,	58
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58
SIMAGCHEM CORP	58
TargetMol Chemicals Inc.	58

View Lastest Price from Dropropizine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2022-02-25	Dropropizine 17692-31-8	US $1.10 / g	1g	99.00%	100 Tons	Dideu Industries Group Limited
2021-07-02	Dropropizine 17692-31-8	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2020-04-29	Dropropizine 17692-31-8	US $0.10 / KG	1KG	99.0%	1000 tons	Shaanxi Dideu Medichem Co. Ltd

Dropropizine
17692-31-8
US $1.10 / g
99.00%
Dideu Industries Group Limited

Dropropizine
17692-31-8
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Dropropizine
17692-31-8
US $0.10 / KG
99.0%
Shaanxi Dideu Medichem Co. Ltd

Dropropizine Spectrum

Dropropizine(17692-31-8)¹HNMR

17692-31-8(Dropropizine)Related Search:

PHENYL VALERATE 1-Methoxy-2-propyl acetate Hydroxypropyl methyl cellulose 2-Hydroxypropyl-β-cyclodextrin trans-1-Cinnamylpiperazine

Diphenyl ether (R)-(-)-1,2-Propanediol Diprophylline 1-Methoxy-2-propanol Propylene glycol

1,3-Propanediol Poly(propylene glycol) Hydroxypropyl cellulose Hydroxypropyl acrylate PHENYL RESIN

(S)-Dropropizine mociprazine Centpropazine

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3-(4-phenyl-1-piperazinyl)-2-propanediol catabex dipropizine ditustat dopropizin katril larylin 1,2-PROPANEDIOL, 3-(4-PHENYL-1-PIPERAZINYL)- 3-(4-phenylpiperazin-1-yl)propane-1,2-diol 3-(4-Phenyl-1-piperazinyl)1,2- ribex tussilex (+/-)-DROPROPIZINE DROPROPIZINE LABOTEST-BB LT00771927 3-[4-PHENYL-1-PIPERAZINYL]-1,2-PROPANEDIOL gevotuss UCB-1967 3-(4-Phenyl-1-piperazinyl)-1，2-pmpanediol rac Dropropizine 3-(4-phenyl-1-piperazinyl)propane-1,2-diol UCB-196 Dropropizine ISO 9001：2015 REACH (+-)-dropropizine (?-Dropropizine 17692-31-8 Analytical Standards Alphabetic Analytical Chromatography Product Catalog DJ - DZ Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals