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Clinofibrate

Clinofibrate structure

CAS No.: 30299-08-2

Chemical Name:: Clinofibrate

Synonyms: S 8527;lipoclin;bis(oxy);CLINOFIBRATE;Clinofibrate >CLINOFIBRATE (S-8527);Clinofibrate USP/EP/BP;2,2'-(cyclohexyliden...;CLINOFIBRATE(FORR&DONLY);bis(2-methylbutanoic acid)

CBNumber:: CB9333525

Molecular Formula:: C28H36O6

Molecular Weight:: 468.58

MDL Number:: MFCD00865769

MOL File:: 30299-08-2.mol

Last updated:2023-06-08 17:06:36

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Clinofibrate Properties

Melting point	143-145°C
Boiling point	498.6°C (rough estimate)
Density	1.1005 (rough estimate)
refractive index	1.4482 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Sligthly)
form	Solid
pka	3.00±0.10(Predicted)
color	White to Off-White
Merck	14,2357
CAS DataBase Reference	30299-08-2(CAS DataBase Reference)
FDA UNII	0374EZJ8CU

SAFETY

Risk and Safety Statements

RTECS	ES8900000
HS Code	2918.99.4700

Clinofibrate price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	C3100	Clinofibrate >98.0%(HPLC)	30299-08-2	200mg	$93	2024-03-01	Buy
TCI Chemical	C3100	Clinofibrate >98.0%(HPLC)	30299-08-2	1g	$282	2024-03-01	Buy
TRC	C580100	Clinofibrate	30299-08-2	5mg	$50	2021-12-16	Buy
TRC	C580100	Clinofibrate	30299-08-2	100mg	$590	2021-12-16	Buy
Biosynth Carbosynth	FC20487	Clinofibrate	30299-08-2	50mg	$841.5	2021-12-16	Buy

Product number	Packaging	Price	Buy
C3100	200mg	$93	Buy
C3100	1g	$282	Buy
C580100	5mg	$50	Buy
C580100	100mg	$590	Buy
FC20487	50mg	$841.5	Buy

Clinofibrate Chemical Properties,Uses,Production

Chemical Properties

White Solid

Originator

Lipocrin,Sumitomo,Japan,1981

Uses

Clinofibrate is an antilipemic, used as an anti-atherosclerosis agent.

Definition

ChEBI: Clinofibrate is an organic molecular entity.

Manufacturing Process

Into a mixture of 6.0 g of a bishydroxyphenyl derivative, and 44.0 g of methyl ethyl ketone was added 16.2 g of crushed potassium hydroxide or sodium hydroxide. Chloroform was added dropwise into the above mixture with stirring at 20°C to 80°C, and the resultant mixture was heated for 20 hours under reflux to complete the reaction. Thereafter the reaction mixture was concentrated to give a residue. Into the residue was added water. After cooling, the resultant mixture was treated with activated charcoal and acidified by diluted hydrochloric acid or sulfuric acid to give an oily substance. The oily substance was extracted by ether and the ether solution was contacted with aqueous diluted Na2CO3 solution. The separated aqueous layer was washed with ether, acidified and again extracted with ether. The obtained ester layer was dried over anhydrous sodium sulfate and concentrated to give 1.0 g of a crude product which was purified by recrystallization or chromatography, to give crystals MP 143°C to 146°C (decomp.)

Therapeutic Function

Antihyperlipoproteinemic

Clinofibrate Preparation Products And Raw materials

Raw materials

2-Butanone

Preparation Products

Clinofibrate Suppliers

Global( 158)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9320	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29220	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58

Supplier	Advantage
career henan chemical co	58
Xiamen AmoyChem Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Shaanxi Dideu Medichem Co. Ltd	58
Dideu Industries Group Limited	58
AFINE CHEMICALS LIMITED	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
InvivoChem	58

View Lastest Price from Clinofibrate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-08-06	Clinofibrate USP/EP/BP 30299-08-2	US $1.10 / g	1g	99.9%	100 Tons min	Dideu Industries Group Limited
2020-05-12	Clinofibrate 30299-08-2	US $0.00-0.00 / KG	1KG	99.0%	500 MT	Shaanxi Dideu Medichem Co. Ltd
2019-09-02	Clinofibrate 30299-08-2	US $7.00 / KG	1KG	99%	1000KG	Career Henan Chemical Co

Clinofibrate USP/EP/BP
30299-08-2
US $1.10 / g
99.9%
Dideu Industries Group Limited

Clinofibrate
30299-08-2
US $0.00-0.00 / KG
99.0%
Shaanxi Dideu Medichem Co. Ltd

Clinofibrate
30299-08-2
US $7.00 / KG
99%
Career Henan Chemical Co

Clinofibrate Spectrum

Clinofibrate(30299-08-2)¹HNMR

30299-08-2(Clinofibrate)Related Search:

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2-Phenoxybutyric acid (S)-(+)-2-Methylbutyric acid Methylbutyric acid

1of4

2,2’-cyclohexane-1,1-diylbis(p-phenyleneoxy)bis(2-methylbutyricacid) lipoclin 2,2'-(cyclohexylidenebis(4,1-phenyleneoxy))bis(2-methyl)-butanoic acid CLINOFIBRATE CLINOFIBRATE(FORR&DONLY) 1,1-Bis[4'-(1''-carboxy-1''-methylpropoxy)phenyl]cyclohexane Butanoic acid, 2,2'-[cyclohexylidenebis(4,1-phenyleneoxy)]bis[2-methyl- S 8527 2,2'-[(1,1-Cyclohexanediyl)bis(4,1-phenyleneoxy)]bis(2-methylbutanoic acid) 2,2'-[Cyclohexylidenebis(4,1-phenyleneoxy)]bis(2-methylbutyric acid) 2,2'-(cyclohexyliden... 2,2,-((cyclohexane-1,1-diylbis(4,1-phenylene))bis(oxy))bis(2-methylbutanoic acid) 2,2'-((Cyclohexane-1,1-diylbis(4,1-phenylene) bis(2-methylbutanoic acid) bis(oxy) 2,2’-(4,4’-cyclohexylidenediphenoxy)-2,2’-dimethyldibutyricacid 2,2’-cyclohexane-1,1-diylbis(p-phenyleneoxy)bis-(2-methyl-butyricaci CLINOFIBRATE (S-8527) Clinofibrate > 2,2'-(4,4'-Cyclohexylidenediphenoxy)-2,2'-dimethyldibutanoic Acid Clinofibrate USP/EP/BP Clinofibrate (10mM in DMSO) 2,2’-[[Cyclohexane-1,1-diylbis(4,1-phenylene)]bis(oxy)]bis(2-methylbutanoic Acid) 30299-08-2 30298-08-2 C28H36O6 API Inhibitors Aromatics Intermediates & Fine Chemicals Pharmaceuticals