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Adenosine 5'-monophosphate monohydrate

Adenosine 5'-monophosphate monohydrate Structure
Adenosine 5'-monophosphate monohydrate structure
CAS No.
18422-05-4
Chemical Name:
Adenosine 5'-monophosphate monohydrate
Synonyms
A-5'-P;5'-AMP;AMP.H2O;5'-AMPH2;5'-AMP H2O;AMP monohydrate;5'-AMP MONOHYDRATE;5'-AMP=Adenylicacid;Adenosine-5’-phospho;Bucladesine Impurity 4
CBNumber:
CB9343816
Molecular Formula:
C10H16N5O8P
Molecular Weight:
365.24
MDL Number:
MFCD00149360
MOL File:
18422-05-4.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:13
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Adenosine 5'-monophosphate monohydrate Properties

Melting point 183-188 °C (dec.)(lit.)
alpha -48 º (c=2% in 2% NaOH)
FEMA 4224 | ADENOSINE MONOPHOSPHATE; MONOSODIUM, OR DISODIUM ADENYLATE
storage temp. -20°C
solubility H2O: with addition of mild alkalisoluble
form Solid
color White to Off-White
Merck 14,158
BRN 5205540
CAS DataBase Reference 18422-05-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  AU7480500
F  8-10-21
TSCA  Yes
HS Code  2934999090

Adenosine 5'-monophosphate monohydrate price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A2252 Adenosine 5′-monophosphate monohydrate from yeast, ≥97% 18422-05-4 5g $62.8 2024-03-01 Buy
Sigma-Aldrich A2252 Adenosine 5′-monophosphate monohydrate from yeast, ≥97% 18422-05-4 25g $228 2024-03-01 Buy
Sigma-Aldrich A2252 Adenosine 5′-monophosphate monohydrate from yeast, ≥97% 18422-05-4 100g $637 2024-03-01 Buy
TRC A281830 Adenosine 5′-monophosphate monohydrate 18422-05-4 50mg $45 2021-12-16 Buy
ChemScene CS-8159 Adenosine 5′-monophosphate monohydrate 99.07% 18422-05-4 500mg $50 2021-12-16 Buy
Product number Packaging Price Buy
A2252 5g $62.8 Buy
A2252 25g $228 Buy
A2252 100g $637 Buy
A281830 50mg $45 Buy
CS-8159 500mg $50 Buy

Adenosine 5'-monophosphate monohydrate Chemical Properties,Uses,Production

Pharmacodynamics

Adenosine monophosphate, also known as 5'-adenylic acid and abbreviated AMP, is a nucleotide that is found in RNA. It is an ester of phosphoric acid with the nucleoside adenosine. AMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase adenine. AMP is used as a dietary supplement to boost immune activity, and is also used as a substitute sweetener to aid in the maintenance of a low-calorie diet.

Chemical Properties

White crystalline powder

Uses

Adenosine 5′-monophosphate (5′AMP) is suitable for use as

  • a reagent in the synthesis of adenosine-5′-phosphoimidazolide
  • an activator of phosphorylase b in the polymerization reaction for the synthesis of branched polysaccharides
  • an inhibitor of endogenous NMN adenylyltransferase (NMNAT) activity that converts NMN to NAD+

Uses

Nutrient;Ca++ channel block

Definition

ChEBI: Adenosine 5'-monophosphate monohydrate is a purine ribonucleoside monophosphate.

Biochem/physiol Actions

Adenosine 5′-monophosphate (5′-AMP) has many uses in nature. 5′-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). AMP inhibits dephosphorylation of AMPK and promotes phosphorylation of AMPK by upstream kinases.

Purification Methods

The acid has been recrystallised from H2O (fine needles) and is freely soluble in boiling H2O. It crystallises also from H2O on addition of acetone. Alternatively purify it by chromatography on Dowex 1 (in formate form), eluting with 0.25M formic acid. It is then adsorbed onto charcoal (which had been boiled for 15minutes with M HCl, washed free of chloride and dried at 100o) and recovered by stirring three times with isoamyl alcohol/H2O (1:9 v/v). The aqueous layer from the combined extracts is evaporated to dryness under reduced pressure, and the product is crystallised twice from hot H2O. [Morrison & Doherty Biochem J 79 433 1961]. It has max 259nm ( 15,400) in H2O at pH 7.0. [Alberty et al. J Biol Chem 193 425 1951, Martell & Schwarzenbach Helv Chim Acta 39 653 1956]. The acridinium salt has m 208o [Baddiley & Todd J Chem Soc 648 1947, Pettit Synthetic Nucleotides, van Nostrand-Reinhold, NY, Vol 1 252 1972, NMR: Sarma et al. J Am Chem Soc 96 7337 1974, Norton et al. J Am Chem Soc 98 1007 1976, IR of diNa salt: Miles Biochem Biophys Acta 27 324 1958]. [Beilstein 26 III/IV 3615.]

Adenosine 5'-monophosphate monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Adenosine 5'-monophosphate monohydrate Suppliers

Global( 189)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 6992 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Creative Enzymes 		1-516-855-7709 info@creative-enzymes.com United States 8748 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418671 sales@tnjchem.com China 34572 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
AFINE CHEMICALS LIMITED 		0571-85134551 info@afinechem.com CHINA 15377 58
Finetech Industry Limited 		+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9702 58
Wuhan Fortuna Chemical Co., Ltd 		+86-27-59207850 +86-13986145403 info@fortunachem.com China 5988 58
Supplier Advantage
career henan chemical co 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
Chongqing Chemdad Co., Ltd 		58
Creative Enzymes 		58
TargetMol Chemicals Inc. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
AFINE CHEMICALS LIMITED 		58
Finetech Industry Limited 		58
Wuhan Fortuna Chemical Co., Ltd 		58

View Lastest Price from Adenosine 5'-monophosphate monohydrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Adenosine 5'-monophosphate monohydrate pictures 2022-09-30 Adenosine 5'-monophosphate monohydrate
18422-05-4
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
Adenosine 5'-monophosphate monohydrate pictures 2021-09-29 Adenosine 5'-monophosphate monohydrate
18422-05-4
 US $0.00-0.00 / Kg/Drum 1KG 98%min 500kgs WUHAN FORTUNA CHEMICAL CO., LTD
Adenosine 5'-monophosphate monohydrate pictures 2019-07-06 Adenosine 5'-monophosphate monohydrate
18422-05-4
 US $1.00 / KG 1KG 95%-99.99% 1kg-10MT Career Henan Chemical Co

Adenosine 5'-monophosphate monohydrate Spectrum

Adenosine 5'-monophosphate monohydrate(18422-05-4)1HNMRAdenosine 5'-monophosphate monohydrate(18422-05-4)IRAdenosine 5'-monophosphate monohydrate(18422-05-4)Raman

18422-05-4(Adenosine 5'-monophosphate monohydrate)Related Search:

MELIBIOSE 2-Amino-2-methyl-1-propanol Cyclic AMP Adenosine Adenosine 5'-monophosphate
ADP Adenosine5'-(tetrahydrogen triphosphate), disodiuM salt, trihydrate (9CI) ADENOSINE 5'-TRIPHOSPHATASE Vidarabine monophosphate ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT
ATP disodium salt ADENOSINE 5'-DIPHOSPHATE SODIUM SALT ADENOSINE 5'-TRIPHOSPHATE DISODIUM SAL& Adenosine 3',5'-cyclic monophosphate sodium salt NADP sodium salt
Nadph tetrasodium salt FLAVIN ADENINE DINUCLEOTIDE NAD+

1of4

ADENOSINE 5'-MONOPHOSPHATE FREE ACID97+% FROM YEAS 5'-AMP=Adenylicacid ADENOSINE-5'-MONOPHOSPHATE 1-HYDRATE 5'-AMP H2O 5'-AMP MONOHYDRATE ADENOSINE 5'-MONOPHOSPHATE MONOHYDRATE ADENOSINE 5'-MONOPHOSPHORIC ACID MONOHYDRATE ADENYLIC ACID MONOHYDRATE A-5'-P Adenosine-5'-monophosphoric acid monohydrate >96% AMP monohydrate 5-Adenylic acid, monohydrate Adenosine-5''-monophosphoric acid (and/or unspecified salts) 5'-AMP 5'-AMPH2 Adenosine-5'-Monophosphoric acid Monhydrate >96% 5μ-AMP, Adenylic acid from muscle, AMP 5μ-Adenylic acid, 5μ-AMP, A-5μ-P, AMP Adenosine-5'-monophosphate(AMP),free acid Adenosine 5′-monophosphate monohydrate,5′-AMP, 5′-Adenylic acid, A-5′-P, AMP Adenosine-5’-phospho AMP.H2O 5'-Adenylic acid, hydrate (1:1) Adenosine-5'-monophosphate monohydrate≥ 95% (HPLC) [(2R,3R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-2-oxolanyl]methyl dihydrogen phosphate Adenosine 5'-monophosphate monohydrate, from yeast,≥97% Adenosine 5'-Monophosphate, Free Acid, from Yeast(AMP) Bucladesine Impurity 4 Adenosine- 5-monophosphate monohydrate, free acid ((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate hydrate Bucladesine Impurity 5 Enzastaurin Impurity 9 Adenosine 5'-monophosphate monohydratefrom yeast Adenosine 5'-monophosphate monohydrate 18422-05-4 C10H12N5O6PH2O C10H16N5O8P BioChemical Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleotides nucleoside Nucleotides and Nucleic Acids