5-Chlorovaleryl chloride
- CAS No.
- 1575-61-7
- Chemical Name:
- 5-Chlorovaleryl chloride
- Synonyms
- 5-CHLOROPENTANOYL CHLORIDE;5-Chlorvalerylchlorid;5-CHLOROVALEROYL CHLORIDE;orovaL;5-Chlorovaleryl;Apixaban Impurity 56;5-chloro aMyl chloride;5 - chlorine e chloride;5-chloro-valerylchlorid;5-chlorvaleryl chloride
- CBNumber:
- CB9348033
- Molecular Formula:
- C5H8Cl2O
- Molecular Weight:
- 155.02
- MDL Number:
- MFCD00000758
- MOL File:
- 1575-61-7.mol
- MSDS File:
- SDS
| Boiling point | 38-39 °C0.15 mm Hg(lit.) |
|---|---|
| Density | 1.206 g/mL at 20 °C |
| refractive index |
n |
| Flash point | 195 °F |
| storage temp. | Store below +30°C. |
| solubility | Acetonitrile (Slightly), Chloroform (Sparingly) |
| form | Liquid |
| color | Clear colorless to slightly yellow |
| Specific Gravity | 1.200 |
| PH | <7 (H2O, 20℃) |
| explosive limit | 2.0-10.2%(V) |
| Water Solubility | reacts |
| Sensitive | Moisture Sensitive |
| BRN | 1745182 |
| Stability | Corrosive, Moisture Sensitive |
| InChIKey | SVNNWKWHLOJLOK-UHFFFAOYSA-N |
| CAS DataBase Reference | 1575-61-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H314 | |||||||||
| Precautionary statements | P270-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| Hazard Codes | C,T | |||||||||
| Risk Statements | 22-34-23-23/34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 3265 8/PG 2 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | YV9108000 | |||||||||
| F | 10-19-21 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29159000 | |||||||||
| NFPA 704 |
|
5-Chlorovaleryl chloride price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 125245 | 5-Chlorovaleroyl chloride 96% | 1575-61-7 | 10g | $77.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 125245 | 5-Chlorovaleroyl chloride 96% | 1575-61-7 | 50g | $233.4 | 2024-03-01 | Buy |
| TCI Chemical | C1789 | 5-Chlorovaleryl Chloride >98.0%(GC)(T) | 1575-61-7 | 5g | $41 | 2024-03-01 | Buy |
| TCI Chemical | C1789 | 5-Chlorovaleryl Chloride >98.0%(GC)(T) | 1575-61-7 | 25g | $116 | 2024-03-01 | Buy |
| Alfa Aesar | H56237 | 5-Chlorovaleroyl chloride, 98% | 1575-61-7 | 50g | $262 | 2024-03-01 | Buy |
5-Chlorovaleryl chloride Chemical Properties,Uses,Production
Description
5-Chlorovaleryl chloride is an important synthetic intermediate of pyrazole herbicides. 5-Chloropentanoyl chloride is used as the raw material of 1,1,7-trichloro-1-hepten-3-one, and then the third-generation pyrazole herbicides can be synthesized. Pyrazole herbicides have the characteristics of ultra-efficient herbicidal activity, high selectivity, extremely low mammalian toxicity and good environmental characteristics, and have become a hot spot in the research and development of herbicides in the world in recent years.
Chemical Properties
clear colourless to slightly yellow liquid
Uses
5-Chlorovaleroyl chloride (5-CVC) has been used in the development and validation of a GC-FID method for the analysis of low level impurities present in 5-CVC. It has been used in the synthesis of anion-exchange resins by acylation of polystyrene/divinylbenzene and subsequent amination with trimethylamine. It is commonly used as alkylating agent in the synthesis of pharmaceutical intermediates and other specialty chemicals.
Application
5-Chlorovaleryl chloride is an important medicine and pesticide intermediate. It is pharmaceutically mainly for the manufacture of the medicine Cilostazole (Cilostazol) for anti-platelet aggregation, protection of vascular endothelial cells, and atherosclerosis.5-Chlorovaleryl Chloride is also for the production of paddy rice New-type wide-spectrum weedicide pyraclonil (Pyraclonil).
General Description
5-Chlorovaleroyl chloride is commonly used as alkylating agent in the synthesis of pharmaceutical intermediates and other specialty chemicals.
Flammability and Explosibility
Not classified
Synthesis
In the existing process, producing 5-Chlorovaleryl chloride using 1,4-dichlorobutane as raw material requires a three-step reaction. First, 1,4-dichlorobutane and sodium cyanide solution are combined to form 5-chlorovaleronitrile. Then, the prepared 5-chlorovaleronitrile is hydrolyzed in concentrated hydrochloric acid to form 5-chlorovaleric acid. Finally, 5-chlorovaleronitrile reacts with thionyl chloride to generate 5-chlorovaleryl chloride.
5-Chlorovaleryl chloride Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 | sophieliu@speranzachem.com | China | 723 | 55 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7377 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9352 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
View Lastest Price from 5-Chlorovaleryl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-18 | 5-Chlorovaleryl chloride
1575-61-7
|
US $20.00 / KG | 1KG | 99% | 300MT/year | Speranza Chemical Co., Ltd. | |
 |
2024-01-18 | 5-Chlorovaleryl chloride
1575-61-7
|
US $6.00-0.60 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-08-11 | 5-Chlorovaleryl chloride
1575-61-7
|
US $0.00-0.00 / kg | 1kg | 99% | 20 tons | Hebei Yanxi Chemical Co., Ltd. |
-
- 5-Chlorovaleryl chloride
1575-61-7
- US $20.00 / KG
- 99%
- Speranza Chemical Co., Ltd.
-
- 5-Chlorovaleryl chloride
1575-61-7
- US $6.00-0.60 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 5-Chlorovaleryl chloride
1575-61-7
- US $0.00-0.00 / kg
- 99%
- Hebei Yanxi Chemical Co., Ltd.