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Solvent Green 7

CAS No.
6358-69-6
Chemical Name:
Solvent Green 7
Synonyms
HPTS;CI 59040;PYRANINE;8-Hydroxypyrene-1,3,6-trisulfonic acid;MIDORI204;8-hydroxypyrene-1,3,6-trisulfonate;Trisodium 8-hydroxypyrene-1,3,6-trisulphonate;1,3,6-Pyrenetrisulfonicacid,8-hydroxy-,trisodiumsalt;GREEN 8;Pyranin
CBNumber:
CB9402700
Molecular Formula:
C16H7Na3O10S3
Molecular Weight:
524.39
MDL Number:
MFCD00037575
MOL File:
6358-69-6.mol
MSDS File:
SDS
Last updated:2023-11-28 19:11:11

Solvent Green 7 Properties

Melting point 62-63.5 °C(lit.)
Boiling point 171-178 °C10 mm Hg(lit.)
Density 2.15
vapor pressure 0Pa at 25℃
Flash point 250 °C
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility methanol: 0.1 g/mL, clear
Colour Index 59040
form Powder
pka 7.3, (at 22℃)
color yellow
Water Solubility 300 g/L (25 ºC)
λmax 403 nm (Buffer pH 4.0); 454 nm (Buffer pH 9.0)
Merck 7954
BRN 4107272
Major Application Adhesives; agrochemicals; ammonia sensor; carbon dioxide sensor; oxygen sensor; anionic surfactants sensor; measuring the size of the organoclay aggregates; detecting cracks/flaws in metallic surfaces, refrigerant leaking; detergents; correction fluid; highlighters; inks; markers; paints; pencils; toners; chemically amplified resist; color filters; chemiluminescent materials; electrophoretic display (EPD) film materials; electroluminescent displays/materials; fuel cell; lasers; liquid crystal displays; luminescent materials; nanoparticles; papers; photoresist processes; photonic ionic liquids; soils; solar cell; sol–gel materials/processes/thin films; sonophotoluminescence; water tracers; evaluating liquid water flow in wood during drying
Biological Applications Antiperspirants; bath preparations; cleansing products; cosmetics; contact lens; hair dyes; hygiene products/soaps; food products; controlled-release system for proteins; drug delivery; in ophthalmology/retinal surgery; sugar sensors (glucose, fructose, lactose, sucrose); as a substrate for measuring acetylcholinesterase (AChE) activity, carbonic anhydrase activity, esterases activity, β-glucuronidase activity, lipase activity, acidic/alkaline phosphatases activity, pyrophosphatase activity, sucrose phosphorylase (SPO) activity, phosphoglucomutase (PGM) activity; treating cancer, infection, immune/autoimmune disease, mastitis, tonsillitis, tuberculosis
LogP -3.97 at 25℃
FDA 21 CFR 74.1208; 74.2208
CAS DataBase Reference 6358-69-6(CAS DataBase Reference)
EWG's Food Scores 1-3
FDA UNII I2W85YOX9L
EPA Substance Registry System C.I. Solvent Green 7 (6358-69-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338-P280a-P304+P340-P405-P501a
Hazard Codes  Xn,Xi
Risk Statements  36/37/38
Safety Statements  36/37-37/39-26-36
WGK Germany  3
RTECS  UR2700000
TSCA  Yes
HS Code  29089990
NFPA 704
1
2 0

Solvent Green 7 price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H1529 8-Hydroxypyrene-1,3,6-trisulfonic acid trisodium salt ≥96% 6358-69-6 1g $103 2024-03-01 Buy
Sigma-Aldrich 16214 Solvent Green 7 hydrate analytical standard 6358-69-6 100mg $74.8 2021-12-16 Buy
Alfa Aesar L11252 Pyranine 6358-69-6 5g $61.1 2024-03-01 Buy
Alfa Aesar L11252 Pyranine 6358-69-6 25g $211 2024-03-01 Buy
Cayman Chemical 30080 8-Hydroxypyrene-1,3,6-trisulfonic Acid (sodium salt) 6358-69-6 500mg $59 2024-03-01 Buy
Product number Packaging Price Buy
H1529 1g $103 Buy
16214 100mg $74.8 Buy
L11252 5g $61.1 Buy
L11252 25g $211 Buy
30080 500mg $59 Buy

Solvent Green 7 Chemical Properties,Uses,Production

Chemical Properties

yellow to green-yellow powder

Uses

Pyranine is used as a fluorescent pH indicator with emission change in the physiological pH range. It acts as a dye in optical sensor applications. It finds application as a coloring agent and biological stain. It is also used in the measurement of pH of intracellular fluid in the cells.

Preparation

commonly known as Pyranine. Pyrene-1,3,6,8-tetrasulfonic acid?and 15 ~ 20% sodium hydroxide reflux, also can use ammonia water on hydrolysis reaction, this condition the product contains APTS(8-Aminopyrene-1,3,6-trisulfonic acid?).

Definition

ChEBI: Pyranine is an organic sodium salt. It has a role as a fluorochrome. It contains a pyranine(3-). It derives from a hydride of a pyrene.

Flammability and Explosibility

Not classified

Biological Activity

Pyranine (HPTS; Solvent Green 7) is a pH-sensitive fluorescent indicator. Pyranine is a class of fluorescent chemosensors for Cu+ ions (λex=450 nm, λem=510 nm).

in vitro

Pyranine is capable of discriminating ranges of cations from the Cu + ion, even in competing environment. Pyranine displays a rapid fluorescence response (t 1/2 =1.66 min) towards the Cu + ion, and the micromolar detection limit enables the detection of the ion in environmental samples. The observed stoichiometry of complexation between Pyranine and Cu + is 2:1.The pH-sensitive fluorescent indicator Pyranine is studied to determine its usefulness as probes for the living cornea and anterior chamber. Adequate concentrations are reached in the cornea and anterior chamber after topical administration; measurements can be made by fluorophotometry for many hours. The pH is calculated by measuring the ratio of fluorescent intensity at two excitation wavelengths, I463/I404, a measurement which is dependent on pH but independent of the concentration of the fluorophore and other variables which can alter the intensity. In the rabbit eye, Pyranine in the cornea and anterior chamber is observed to undergo easily measurable changes in fluorescent ratios associated with lid closure and contact lens wear, indicating its sensitivity to mild changes in pH.

Properties and Applications

yellow green. Slightly soluble in glacial acetic acid, 30% hydrochloric acid, insoluble in acetic acid and 10% hydrochloric acid. Mainly used in medicine and cosmetics coloring.

Standard Light Fastness Heat-resistant(℃) water Sodium Carbonate(5%) Hydrochloric acid(5%)
Melting point Stable
ISO Dissole

Purification Methods

Purify the salt by chromatography with an alumina column, and elute with n-propanol/water (3:1, v/v). Recrystallise it from aqueous acetone (5:95, v/v) using decolorising charcoal. [Beilstein 1 III 565.] IRRITANT.

Solvent Green 7 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 270)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5993 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5909 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Shenyang Simchoice Chemical Co.,Ltd
+86-024-23769576 +86-15040101888 sales@simchoicechem.com China 255 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58

View Lastest Price from Solvent Green 7 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Solvent Green 7 pictures 2023-11-28 Solvent Green 7
6358-69-6
US $20.00-10.00 / kg 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
Solvent Green 7 pictures 2023-09-06 Solvent Green 7
6358-69-6
US $30.00-10.00 / KG 50KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
Solvent Green 7 pictures 2023-07-19 Solvent Green 7
6358-69-6
US $10.00 / KG 1KG 99% 20 tons Wuhan wingroup Pharmaceutical Co., Ltd
  • Solvent Green 7 pictures
  • Solvent Green 7
    6358-69-6
  • US $20.00-10.00 / kg
  • 0.99
  • Hebei Yanxi Chemical Co., Ltd.
  • Solvent Green 7 pictures
  • Solvent Green 7
    6358-69-6
  • US $30.00-10.00 / KG
  • 99%
  • Hebei Guanlang Biotechnology Co., Ltd.
  • Solvent Green 7 pictures
  • Solvent Green 7
    6358-69-6
  • US $10.00 / KG
  • 99%
  • Wuhan wingroup Pharmaceutical Co., Ltd
SOLVENT GREEN 7 PYRANINE 108 PYRANINE GREEN PYRANINE, TRISODIUM SALT VERAPAMIL INTERMEDIATES GREEN 8 8-HYDROXY-1,3,6-PYRENETRISULFONIC ACID, TRISODIUM SALT (DYE CONTENT CA. 75%) 1-HYDROXYPYRENE-3,6,8-TRISULFONIC ACID, TRISODIUM Pyrene, 1-hydroxy-3,6,8-trisulfonic acid, trisodium salt 8-Hydroxy-1,3,6-pyrenetrisulfonic acid trisodium salt, laser grade, pure 8-Hydroxy-1,3,6-pyrenetrisulfonic acid trisodium salt, pure, 98% 6-hydroxy-1,3,8-pyrenetrisulfonic acid trisodium salt 1,3,6-PYRENETRISULPHONICACID,8-HYDROXY-,TRISODIUMSALT Piranine Conc Hodgsons D & C Green No. 8 HPTS, Pyranine, Solvent Green 7, Trisodium 8-hydroxypyrene-1,3,6-trisulfonate 8-Hydroxy-1,3,6-pyrenetrisulfonic acid trisodium salt, 98%, pure Solvent green 7 (C.I. 59040) 8-HYDROXY-1,3,6-PYRENETRISULFONIC ACID TRISODIUM SALT, LASER GRADE D AND C GREEN NO 8 CYANOMETHYL-3,4-DIMETHOXYBENZENE HOMOVERATRONITRIL HPTS TRISODIUM SALT LABOTEST-BB LT00159917 8-Hydroxy-1,3,6-pyrenetrisulfonic acid trisodium salt,pure,laser grade d&cgreenno.8 greenno.204 pyranineconcentrated trisodium1-hydroxy-3,6,8-pyrenetrisulfonate 3,4-DIMETHYLOXYPHENYLACETONITRILE 3,4-DIMETHYLOXY PHENYLACETONOTRILE 3,4-DIMETHOXYPHENYLACETONITIRLE 1-HYDROXYPYRENE-3,6,8-TRISULFONIC ACID TRISODIUM SALT HPTS [pyranine],,[8-hydroxypyrene-1,3,6-trisulfonic acid, trisodiuM salt] 8-Hydroxypyrene-1,3,6-trisulfonic acid trisodiuM salt >=97% Pyranin 8-HYDROXY-1,3,6-PYRENETRISULFONIC ACID TRISODIUM SALT 8-HYDROXYPYRENE-1,3,6-TRISULFONIC ACID, TRISODIUM SALT C Green No. 8 Sodium 8-hydroxypyrene-1,3,6-trisulfonate Solvent Green 7 hydrate 11389green 3,6-pyrenetrisulfonicacid,8-hydroxy-trisodiumsalt 8-hydroxypyrene-1,3,6-trisulfonicacidsodiumsalt c.i.solventgreen7 c.i.solventgreen9 8-Hydroxypyrene-1,3,6-trisulfonic acid, trisodium salt [HPTS] *CAS 6358-69-6* 1,3,6-Pyrenetrisulfonic acid, 8-hydroxy-, sodium salt (1:3) 8-Hydroxypyrene-1,3,6-trisulfonic Acid Trisodium Salt (Technical Grade) Pyranine (HPTS Solvent Green 7 ISO 9001:2015 REACH Transparent green b Fluorescent Yellow Adsorption Indicator C.I.Solvent Green 7:C.I.59040 Solvent Green 7 6358-69-6 PYRANINE Trisodium 8-hydroxypyrene-1,3,6-trisulphonate MIDORI204