ChemicalBook >> CAS DataBase List >>I-BET 151 hydrochloride
I-BET 151 hydrochloride
- CAS No.
- 1883545-47-8
- Chemical Name:
- I-BET 151 hydrochloride
- Synonyms
- I-BET 151 hydrochloride;I-BET 151 dihydrochloride;I BET151 dihydrochloride,I-BET-151 dihydrochloride,IBET151 dihydrochloride;7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydroxy-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one dihydrochloride
- CBNumber:
- CB94189029
- Molecular Formula:
- C23H22ClN5O3
- Molecular Weight:
- 451.91
- MDL Number:
- MFCD30182237
- MOL File:
- 1883545-47-8.mol
Last updated:2023-06-30 15:45:59
I-BET 151 hydrochloride price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 4650 | I-BET151dihydrochloride ≥98%(HPLC) | 1883545-47-8 | 10 | $255 | 2021-12-16 | Buy |
| Tocris | 4650 | I-BET151dihydrochloride ≥98%(HPLC) | 1883545-47-8 | 50 | $1045 | 2021-12-16 | Buy |
| TRC | I120058 | I-BET151Dihydrochloride | 1883545-47-8 | 1mg | $125 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BI162773 | I-BET 151 dihydrochloride | 1883545-47-8 | 10mg | $145 | 2021-12-16 | Buy |
| ApexBio Technology | B5670 | I-BET151hydrochloride | 1883545-47-8 | 5mg | $96 | 2021-12-16 | Buy |
I-BET 151 hydrochloride Chemical Properties,Uses,Production
Biological Activity
i-bet 151 dihydrochloride is a bet bromodomain inhibitor that prevents bet from recruiting to chromatin. i-bet 151 induces mll-fusion leukemia cell line apoptosis and g0 / g1 cell cycle arrest in vitro, and reduces bcl2 expression in nomo1 cells. i-bet 151 improves the survival rate of two kinds of mll fusion leukemia mice, and enhances the differentiation of human ipscs into megakaryocytes.[1]. malherbe p, masciadri r, norcross r d, et al. characterization of (r,s)-5,7-di-tert-butyl-3-hydroxy-3-trifluoromethyl-3h-benzofuran-2-one as a positive allosteric modulator of gabab receptors. british journal of pharmacology, 2008, 154(4): 797.
storage
-20°C
I-BET 151 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
I-BET 151 hydrochloride Suppliers
Global( 19)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8015 | 62 |
| Twochem Co.Ltd. | 021-58111628 15800915896 | China | 1988 | 58 | |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Tianjin Kaifu Pharmaceutical Technology Co., Ltd. | 18081075745 | chemflowtech@sina.com | China | 1886 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Wuhan Yingnuo Pharmaceutical Technology Co., Ltd. | +86-027-59232304 15387063101 | 2881924050@qq.com | China | 9892 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Shaanxi Xihua Chemical Industry Co., Ltd | 17691182729 15529505138 | 1021@dideu.com | China | 9950 | 58 |
I-BET 151 hydrochloride
7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydroxy-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one dihydrochloride
I-BET 151 dihydrochloride
I BET151 dihydrochloride,I-BET-151 dihydrochloride,IBET151 dihydrochloride
1883545-47-8