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1-Deoxysphingosine (m18:1(14Z))

1-Deoxysphingosine (m18:1(14Z)) Structure
1-Deoxysphingosine (m18:1(14Z)) structure
CAS No.
2190487-94-4
Chemical Name:
1-Deoxysphingosine (m18:1(14Z))
Synonyms
1-Deoxysphingosine (m18:1(14Z));(2S,3R,14Z)-2-amino-14-octadecen-3-ol;14-Octadecen-3-ol, 2-amino-, (2S,3R,14Z)-
CBNumber:
CB94665752
Molecular Formula:
C18H37NO
Molecular Weight:
283.49
MDL Number:
MFCD34600137
MOL File:
2190487-94-4.mol
Last updated:2023-04-10 09:29:41
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1-Deoxysphingosine (m18:1(14Z)) Properties

Boiling point 404.5±18.0 °C(Predicted)
Density 0.882±0.06 g/cm3(Predicted)
solubility DMF: 10 mg/ml; DMSO: 2 mg/ml; Ethanol: miscible
pka 12.90±0.45(Predicted)

1-Deoxysphingosine (m18:1(14Z)) price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24515 1-Deoxysphingosine (m18:1(14Z)) ≥98% 2190487-94-4 500μg $172 2024-03-01 Buy
Cayman Chemical 24515 1-Deoxysphingosine (m18:1(14Z)) ≥98% 2190487-94-4 1mg $290 2024-03-01 Buy
AK Scientific 1531EN (Z,2S,3R)-2-Aminooctadec-14-en-3-ol 2190487-94-4 1mg $421 2021-12-16 Buy
Product number Packaging Price Buy
24515 500μg $172 Buy
24515 1mg $290 Buy
1531EN 1mg $421 Buy

1-Deoxysphingosine (m18:1(14Z)) Chemical Properties,Uses,Production

Description

1-Deoxysphingosine (m18:1(14Z)) is an atypical sphingolipid that contains a double bond at the n-4 (14Z) native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 It lacks the C1-hydroxyl group necessary for canonical degradation, however, it is metabolized by the cytochrome P450 (CYP) subfamilies CYP4A and CYP4F in MEF cells.2

References

1. Steiner, R., Saied, E.M., Othman, A., et al. Elucidating the chemical structure of native 1-deoxysphingosine J. Lipid Res. 57(7),1194-1203(2016).
2. Alecu, I., Othman, A., Penno, A., et al. Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway J. Lipid Res. 58(1),60-71(2017).

1-Deoxysphingosine (m18:1(14Z)) Preparation Products And Raw materials

Raw materials

Preparation Products

1-Deoxysphingosine (m18:1(14Z)) Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1977 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Supplier Advantage
Yichang Zhongyitai Trading Co., Ltd. 58
Shanghai Hongye Biotechnology Co. Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
1-Deoxysphingosine (m18:1(14Z)) 14-Octadecen-3-ol, 2-amino-, (2S,3R,14Z)- (2S,3R,14Z)-2-amino-14-octadecen-3-ol 2190487-94-4