ChemicalBook >> CAS DataBase List >>Trimethylacetic anhydride
Trimethylacetic anhydride
- CAS No.
- 1538-75-6
- Chemical Name:
- Trimethylacetic anhydride
- Synonyms
- PIVALIC ANHYDRIDE;Bis(2,2-dimethylpropionic)anhydride;Pivalic anydride;Bis(pivalic)anhydride;Pivalic acid anhydride;2,2-Dimethylpropanoicanhydride;2,2-dimethylpropanoyl 2,2-dimethylpropanoate;Pivolic Anhydride;Dipivalic anhydride;PivalicAnhydride>
- CBNumber:
- CB9470666
- Molecular Formula:
- C10H18O3
- Molecular Weight:
- 186.25
- MDL Number:
- MFCD00008842
- MOL File:
- 1538-75-6.mol
- MSDS File:
- SDS
Last updated:2024-04-01 18:07:32
| Boiling point | 193 °C(lit.) |
|---|---|
| Density | 0.918 g/mL at 25 °C(lit.) |
| vapor pressure | 62.1Pa at 25℃ |
| refractive index |
n |
| Flash point | 135 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Miscible with acetonitrile. |
| form | Liquid |
| color | Clear colorless |
| Sensitive | Moisture Sensitive |
| BRN | 386552 |
| InChI | InChI=1S/C10H18O3/c1-9(2,3)7(11)13-8(12)10(4,5)6/h1-6H3 |
| InChIKey | PGZVFRAEAAXREB-UHFFFAOYSA-N |
| SMILES | C(C)(C)(C)C(=O)OC(=O)C(C)(C)C |
| LogP | 2.15 |
| CAS DataBase Reference | 1538-75-6(CAS DataBase Reference) |
| EPA Substance Registry System | Propanoic acid, 2,2-dimethyl-, anhydride (1538-75-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H314 | |||||||||
| Precautionary statements | P210-P233-P240-P280-P303+P361+P353-P305+P351+P338 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 2920 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 9-13-21 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29159000 | |||||||||
| NFPA 704 |
|
Trimethylacetic anhydride price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 143502 | Trimethylacetic anhydride 99% | 1538-75-6 | 25g | $59 | 2024-03-01 | Buy |
| Sigma-Aldrich | 143502 | Trimethylacetic anhydride 99% | 1538-75-6 | 100g | $176 | 2024-03-01 | Buy |
| TCI Chemical | P1414 | Pivalic Anhydride >98.0%(GC) | 1538-75-6 | 25mL | $59 | 2024-03-01 | Buy |
| TCI Chemical | P1414 | Pivalic Anhydride >98.0%(GC) | 1538-75-6 | 250mL | $295 | 2024-03-01 | Buy |
| Alfa Aesar | B22983 | Trimethylacetic anhydride, 99% | 1538-75-6 | 25g | $62.1 | 2024-03-01 | Buy |
Trimethylacetic anhydride Chemical Properties,Uses,Production
Description
Trimethylacetic anhydride is a pivalic acid derivative that is used in organic synthesis. The compound's reaction mechanism is believed to be the formation of an alkanoic acid, which reacts with a hydroxyl group to form an anhydride. Trimethyl acetic anhydride has been shown to have pharmacokinetic properties and can be used as a nonsteroidal anti-inflammatory drug. This compound has also been found to have a matrix effect on crystalline cellulose and is capable of forming nitrogen-containing carboxylic acids.
Chemical Properties
clear colourless liquid
Uses
Trimethylacetic anhydride was used:
- in solid-phase oligonucleotide synthesis
- in kinetic resolution of racemic 2-hydroxy-γ-butyrolactones with diphenylacetic acid
- as acylation and esterification reagent for anilines
- as acylation and esterification reagent for phenols
Uses
A metabolite of a double prodrug (6-dGCV-DPiv
Flammability and Explosibility
Not classified
Trimethylacetic anhydride Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
Global( 239)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Handan Huajun chemicals Co.,Ltd | +86-0310-8166573 +8618630058311 | sales@huajunchem.com | China | 28 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7377 | 58 |
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
| Shanghai Bojing Chemical Co.,Ltd. | +86-86-02137122233 +8613795318958 | bj1@bj-chem.com | China | 298 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1807 | 55 |
| Anhui Royal Chemical Co., Ltd. | +86-25-86655873 +8613962173137 | marketing@royal-chem.com | China | 205 | 55 |
View Lastest Price from Trimethylacetic anhydride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-12 | TRIMETHYLACETIC ANHYDRIDE
1538-75-6
|
US $0.00 / kg | 1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd | |
 |
2024-01-24 | Pivalic anhydride
1538-75-6
|
US $13.00 / kg | 1kg | 99.0% | 1000MT | Handan Huajun chemicals Co.,Ltd | |
 |
2023-12-23 | TRIMETHYLACETIC ANHYDRIDE
1538-75-6
|
US $50.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- TRIMETHYLACETIC ANHYDRIDE
1538-75-6
- US $0.00 / kg
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd
-
- Pivalic anhydride
1538-75-6
- US $13.00 / kg
- 99.0%
- Handan Huajun chemicals Co.,Ltd
-
- TRIMETHYLACETIC ANHYDRIDE
1538-75-6
- US $50.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
1538-75-6(Trimethylacetic anhydride)Related Search:
2,2-DIMETHYLPROPIONIC ANHYDRIDE
2,2-Dimethylpropionic anhydride, Pivalic anhydride
Bis(2,2-dimethylpropionic acid)anhydride
Bis(pivalic acid)anhydride
Dipivalic anhydride
Trimethylacetic anhydride,99%
Propanoic acid, 2,2-dimethyl-, anhydride
Propanoicacid,2,2-dimethyl-,anhydride
Trimethylacetic anhydride,2,2-Dimethylpropionic anhydride, Pivalic anhydride
Trimethylacetic anhy
TriMethylacetic anhydride, 99% 50ML
2,2-Dimethylpropionic Anhydride
Trimethylacetic Anhydride
PIVALIC ANHYDRIDE FOR SYNTHESIS
Propanoic acid,2,2-dimethyl-, 1,1'-anhydride
TriMethylacetic anhydride 99%
Pivalic anhydride, >=98.0% (GC)
TRIMETHYLACETIC ACID ANHYDRIDE
TRIMETHYLACETIC ANHYDRIDE
1,1-Dimethylpropanoic anhydride
2,2-dimethyl-propanoicacianhydride
BIS(TRIMETHYLACETIC) ANHYDRIDE
2,2-DIMETHYLPROPIONIC ACID ANHYDRIDE
PivalicAnhydride>
Adefovir Dipivoxil Impurity 15 (Pivalic Anhydride)
Adefovir Impurity 36
Trimethylacetic Anhydride1538-75-6
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TIANFU-CHEM -TRIMETHYLACETIC ANHYDRIDE
Bis(2,2-dimethylpropionic)anhydride
Bis(pivalic)anhydride
Pivalic acid anhydride
Pivalic anydride
2,2-Dimethylpropanoicanhydride
PIVALIC ANHYDRIDE
2,2-dimethylpropanoyl 2,2-dimethylpropanoate
Pivalic anhydride (7CI, 8CI)
Pivolic Anhydride
Pivalic anhydride,98%
1538-75-6
C10H18O3
CH33CCO2O
Carbonyl Compounds
Carboxylic Acid Anhydrides
Building Blocks
Organic Building Blocks
Aliphatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Aliphatics
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals