ChemicalBook >> CAS DataBase List >>2'-Deoxyuridine 5'-monophosphate disodium salt
2'-Deoxyuridine 5'-monophosphate disodium salt
- CAS No.
- 42155-08-8
- Chemical Name:
- 2'-Deoxyuridine 5'-monophosphate disodium salt
- Synonyms
- dump;DUMP 2NA;2'-dUMP?2Na;dUMP·（Na·salt）;D-UMP DISODIUM SALT;Diquafosol Impurity 22;Diquafosol Impurity 30;dUMP 100mM Sodium Solution;2'-Deoxyuridine 5'-monophosphate;2'-Deoxy-5'-uridylic acid disodium salt
- CBNumber:
- CB9482517
- Molecular Formula:
- C9H14N2NaO8P
- Molecular Weight:
- 332.18
- MDL Number:
- MFCD00065282
- MOL File:
- 42155-08-8.mol
- MSDS File:
- SDS
Last updated:2024-02-07 18:17:11
| storage temp. | -20°C |
|---|---|
| solubility | PBS (pH 7.2): 1 mg/ml |
| form | Powder |
| color | White to Off-white |
| Water Solubility | Soluble in water. |
| CAS DataBase Reference | 42155-08-8(CAS DataBase Reference) |
| FDA UNII | 6AG9V4748N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
2'-Deoxyuridine 5'-monophosphate disodium salt price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D3876 | 2′-Deoxyuridine 5′-monophosphate disodium salt Sigma Grade | 42155-08-8 | 100mg | $256 | 2024-03-01 | Buy |
| Sigma-Aldrich | D3876 | 2′-Deoxyuridine 5′-monophosphate disodium salt Sigma Grade | 42155-08-8 | 1g | $1490 | 2024-03-01 | Buy |
| Alfa Aesar | J64627 | 2'-Deoxyuridine-5'-monophosphate disodium salt, 99% | 42155-08-8 | 250mg | $110 | 2024-03-01 | Buy |
| Alfa Aesar | J64627 | 2'-Deoxyuridine-5'-monophosphate disodium salt, 99% | 42155-08-8 | 1g | $237 | 2024-03-01 | Buy |
| Sigma-Aldrich | D3876 | 2′-Deoxyuridine 5′-monophosphate disodium salt Sigma Grade | 42155-08-8 | 250mg | $487 | 2024-03-01 | Buy |
2'-Deoxyuridine 5'-monophosphate disodium salt Chemical Properties,Uses,Production
Description
2'-Deoxyuridine 5'-monophosphate disodium salt is a nucleoside analog that inhibits the synthesis of DNA and RNA by inhibiting the enzyme thymidylate synthase, which prevents the formation of dTMP from deoxyuridine 5'-triphosphate. 2'-Deoxyuridine 5'-monophosphate disodium salt has been shown to be effective in treating squamous cell cancer and hyperproliferative diseases such as chronic myelogenous leukemia. 2'-Deoxyuridine 5'-monophosphate disodium salt is also used as an antiviral agent against HIV, herpes simplex virus, and varicella zoster virus.
Uses
2?-Deoxyuridine 5?-monophosphate (dUMP) is used by the enzyme thymidylate synthetase (TS) (EC 2.1.1.45) for the de novo production of dTMP. dUMP is used as the reference substrate in studies of dUMP analogues in potential chemotherapy applications.
General Description
2′-Deoxyuridine 5′-monophosphate disodium salt (dUMP) is a substrate for thymidylate synthase and is converted to deoxythymidine monophosphate (dTMP).
Biochem/physiol Actions
2′-Deoxyuridine 5′-monophosphate disodium salt (dUMP) conversion to pyrimidine is inhibited by methotrexate. The inhibition of dUMP to deoxythymidine monophosphate (dTMP) at the methylation step is a key in controlling bacterial and eukaryotic cell growth.
2'-Deoxyuridine 5'-monophosphate disodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
2'-Deoxyuridine 5'-monophosphate disodium salt Suppliers
Global( 173)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Meiya Pharmaceutical Co Ltd | +86-021-33686691 +8618001850931 | sales@meiyapharm.com | China | 57 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | 1057@dideu.com | China | 3783 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10297 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| Zhejiang Huida Biotech Co., LTD | 008613515763466 8615669048680 | wendy@huidabiotech.com | CHINA | 87 | 58 |
| Shanghai Minbiotech Co., Ltd. | +8617315815539 | sales@minbiotech.com | CHINA | 129 | 58 |
View Lastest Price from 2'-Deoxyuridine 5'-monophosphate disodium salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-11 | 2'-Deoxyuridine 5'-monophosphate disodium salt (dUMP-Na2)
42155-08-8
|
US $0.00-0.00 / kg | 0.10000000149011612kg | ≥99.0% | 500 kg | Hangzhou Meiya Pharmaceutical Co Ltd | |
 |
2022-09-27 | 2'-Deoxyuridine 5'-monophosphate disodium salt
42155-08-8
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2021-07-13 | 2′-Deoxyuridine-5′-monophosphate Disodium salt
42155-08-8
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 2'-Deoxyuridine 5'-monophosphate disodium salt (dUMP-Na2)
42155-08-8
- US $0.00-0.00 / kg
- ≥99.0%
- Hangzhou Meiya Pharmaceutical Co Ltd
-
- 2'-Deoxyuridine 5'-monophosphate disodium salt
42155-08-8
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2′-Deoxyuridine-5′-monophosphate Disodium salt
42155-08-8
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
42155-08-8(2'-Deoxyuridine 5'-monophosphate disodium salt)Related Search:
Thymidine-5'-monophosphate disodium salt
Sodium Phosphate, Dibasic
Pamidronate disodium salt
Ethylenediaminetetraacetic acid disodium salt
Broxuridine
1of4
dump
2''-Deoxyuridine-5''-monophosphoric acid disodium salt
2'-deoxyuridine 5'-monophosphate*disodium sigma G
5'-Uridylic acid, 2'-deoxy-, disodium salt
2'-Deoxyuridine-5'-monophosphate,sodiumsalt
2'-DEOXYURIDINE 5'-MONOPHOSPHATEDISODIUM SIGMA GRA
2''-DEOXYURIDINE 5''-MONOPHOSPHATE DISODIUM SALT (DUMP-NA2)
2'-Deoxy-5'-uridylic acid disodium salt
2'-Deoxyuridine 5'-(phosphoric acid disodium) salt
2'-DEOXYURIDINE 5'-MONOPHOSPHATE DISODIUM SALT
dUMP, 2'-Deoxyuridine-5'-Monophosphate, disodiuM salt
DUMP 2NA
D-UMP DISODIUM SALT
Sodium ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl phosphate
2'-dUMP?2Na
dUMP·（Na·salt）
2′-Deoxyuridine5′-mono-phos-phatedisodiumsal
2'-Deoxyuridine 5'-monophosphate (disodium)
Diquafosol Impurity 22
[(2R,3S,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl phosphate
[(2R,3S,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate
2`-Deoxyuridine-5`-Monophosphate Disodium Salt (dUMP-Na2) extrapure, 98%
2′-Deoxyuridine-5′-monophosphate disodium salt [dUMP·(Na·salt)
Deoxyuridine 5′-monophosphate (sodium salt)
Diquafosol Impurity 30
Disodium 2'-deoxy-5'-O-phosphonatouridine
dUMP 100mM Sodium Solution
2'-Deoxyuridine 5'-monophosphate
2'-Deoxyuridine 5'-monophosphate disodium salt
42155-08-8
C9H11N2Na2O8P
C9H11N2O8PNa2
Metabolites and Cofactors on the Metabolic Pathways Chart
Metabolic Pathways
Nucleotide
Metabolomics
BioChemical
Nucleotide