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Isopropyl myristate

Chemical Properties Content Analysis Applications Production Method Toxicity
Isopropyl myristate
Isopropyl myristate
CAS No.
110-27-0
Chemical Name:
Isopropyl myristate
Synonyms
IPM;D 50;IPM-R;IPM-EX;Promyr;IPM 100;BISOMEL;Isomyst;Revenge;ESTERGEL
CBNumber:
CB9482638
Molecular Formula:
C17H34O2
Formula Weight:
270.45
MOL File:
110-27-0.mol

Isopropyl myristate Properties

Melting point:
-5°C
Boiling point:
193 °C20 mm Hg(lit.)
Density 
0.85 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.434(lit.)
FEMA 
3556 | ISOPROPYL MYRISTATE
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
<0.05mg/l
form 
Liquid
color 
Clear
Water Solubility 
Miscible with alcohol. Immiscible with water and glycerol.
Merck 
5215
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference
110-27-0(CAS DataBase Reference)
NIST Chemistry Reference
Isopropyl Myristate(110-27-0)
EPA Substance Registry System
Tetradecanoic acid, 1-methylethyl ester(110-27-0)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  -
RTECS  XB8600000
TSCA  Yes
HS Code  29159080
Hazardous Substances Data 110-27-0(Hazardous Substances Data)
Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.

Isopropyl myristate price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1350400 Isopropyl myristate United States Pharmacopeia (USP) Reference Standard 110-27-0 500mg $348.4 2017-11-08 Buy
Sigma-Aldrich 172472 Isopropyl myristate 98% 110-27-0 1l $162 2017-11-08 Buy
Alfa Aesar A18111 Isopropyl tetradecanoate, 98% 110-27-0 100ml $36 2017-11-08 Buy
Alfa Aesar A18111 Isopropyl tetradecanoate, 98% 110-27-0 500ml $77.6 2017-11-08 Buy
Sigma-Aldrich 172472 Isopropyl myristate 98% 110-27-0 25ml $38.6 2017-11-08 Buy

Isopropyl myristate Chemical Properties,Uses,Production

Chemical Properties

It is a colorless and odorless liquid, and miscible with vegetable oil. It is not easy to be either hydrolyzed or become rancid. The refractive index nD20 is 1.435~1.438, and the relative density (20°C) is 0.85~0.86.

Content Analysis

Weight 1.5 g sample. Then it is determined by the method ester assay (OT-18). The equivalent factor (e) in the calculation is 135.2. Or it is determined by a non-polar column method of gas chromatography (GT-10-4).

Applications

Production Method

It is a product of esterification of myristic acid derived from re-steamed coconut coil with isopropyl alcohol.
(1)  200 kg myristic acid and 450 kg isopropyl alcohol were added into the reaction vessel in turn. After mixing, 360 kg sulfuric acid (98%) was added. The reaction mixture was heated to reflux for 10 hours. Isopropyl alcohol was then recovered, washed with ice water, and neutralized with Na2CO3 aqueous solution (10%). Under normal pressure, isopropyl alcohol and water were distilled. While under reduced pressure, isopropyl myristate was distilled (185°C/1.0kPa~195°C/2.7kPa).
(2) 90 kg isopropyl alcohol was added into the reaction vessel and then sulfuric acid as catalyst, with 5% of the total amount, was added. During mixing, 228 kg myristic acid was added slowly. The mixture was heated to reflux and water was continuously separated. Until no water was separated, the reaction temperature was reduced and probe was obtained to measure the acid value. When the acid value reached 1.5 mg KOH/g, the reaction was completed. Alkali was then added for neutralization. After the removal of water under reduced pressure, the pressure was further reduced for dealcoholization until the acid value was 0.05~1.0 mg KOH/g. The final product is then isopropyl myristate.

Toxicity

ADI is not regulated (FAO/WHO, 2001).

Chemical Properties

colourless liquid of low viscosity

Isopropyl myristate Preparation Products And Raw materials

Raw materials

Preparation Products


Isopropyl myristate Suppliers

Global( 204)Suppliers
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Capot Chemical Co.,Ltd.
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J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
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Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40403 62
future industrial shanghai co., ltd 021-61552785,400-0066-400
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Alfa Aesar 400-610-6006; 021-67582000
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