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1-(2-Methoxyphenyl)piperazine

CAS No.
35386-24-4
Chemical Name:
1-(2-Methoxyphenyl)piperazine
Synonyms
2-MPP;D 15157;AKOS BBS-00003584;TIMTEC-BB SBB003620;RARECHEM AH CK 0126;2-Piperazinoanisole;Urapidil Impurity 6;LABOTEST-BB LT00233095;1-(o-Anisyl)piperazine;2-(1-PIPERAZINYL)ANISOLE
CBNumber:
CB9669765
Molecular Formula:
C11H16N2O
Molecular Weight:
192.26
MDL Number:
MFCD00005958
MOL File:
35386-24-4.mol
MSDS File:
SDS
Last updated:2023-05-15 10:43:17

1-(2-Methoxyphenyl)piperazine Properties

Melting point 35-40 °C (lit.)
Boiling point 130-133 °C/0.1 mmHg (lit.)
Density 1.095 g/mL at 25 °C (lit.)
refractive index n20/D 1.575(lit.)
Flash point >230 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Liquid After Melting
pka 8.98±0.10(Predicted)
color Clear colorless to yellow
Water Solubility Soluble in chloroform, ethyl acetate, and methanol. Insoluble in water
Sensitive Air Sensitive
BRN 167888
InChI InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3
InChIKey VNZLQLYBRIOLFZ-UHFFFAOYSA-N
SMILES N1(C2=CC=CC=C2OC)CCNCC1
LogP 1.67
CAS DataBase Reference 35386-24-4(CAS DataBase Reference)
FDA UNII 81NJO1330A

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
Hazard Codes  C,Xi
Risk Statements  34-36/37/38
Safety Statements  26-36/37/39-45-28A-36
RIDADR  UN 3263 8/PG 3
WGK Germany  3
3-10
Hazard Note  Irritant
HazardClass  8
PackingGroup 
HS Code  29349990
NFPA 704
1
2 0

1-(2-Methoxyphenyl)piperazine price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M22601 1-(2-Methoxyphenyl)piperazine 98% 35386-24-4 5g $44 2024-03-01 Buy
Sigma-Aldrich M22601 1-(2-Methoxyphenyl)piperazine 98% 35386-24-4 25g $104 2024-03-01 Buy
TCI Chemical M0883 1-(2-Methoxyphenyl)piperazine >98.0%(GC)(T) 35386-24-4 5g $33 2024-03-01 Buy
TCI Chemical M0883 1-(2-Methoxyphenyl)piperazine >98.0%(GC)(T) 35386-24-4 25g $84 2024-03-01 Buy
Alfa Aesar A15819 1-(2-Methoxyphenyl)piperazine 98% 35386-24-4 5g $34.4 2023-06-20 Buy
Product number Packaging Price Buy
M22601 5g $44 Buy
M22601 25g $104 Buy
M0883 5g $33 Buy
M0883 25g $84 Buy
A15819 5g $34.4 Buy

1-(2-Methoxyphenyl)piperazine Chemical Properties,Uses,Production

Chemical Properties

clear colorless to yellow liquid after melting

Uses

1-(2-Methoxyphenyl)piperazine can be used:

  • To functionalize pyrazolylvinyl ketones via Aza-Michael addition reaction.
  • To prepare cyclic amine substituted Tr?ger′s base derivatives.
  • To prepare functionalized bis(mercaptoimidazolyl)borates by reacting with the activated ester, [(1-methyl-2-mercaptoimidazol-5-yl)carbonyl]succinimide.

Uses

It is used as pharmaceutical intermediate. N-alkylated 1-(2-methyoxyphenyl)piperazines markedly improved affinity and selectivity of the dopamine D3 receptor which is recognized as a potential therapeutic target for the treatment of various neurological and psychiatric disorders.

Uses

A piperazine derivative and a selective antagonist at D3 receptors that influences the expression of cocaine-induced conditioned place preference (CPP).

Definition

ChEBI: 1-(2-methoxyphenyl)piperazine is a member of piperazines.

Global( 318)Suppliers
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TOKYO CHEMICAL INDUSTRY CO., LTD.
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Capot Chemical Co.,Ltd.
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Henan Tianfu Chemical Co.,Ltd.
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Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
Wuhan Chemwish Technology Co., Ltd
027-67849912 sales@chemwish.com CHINA 10828 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58

View Lastest Price from 1-(2-Methoxyphenyl)piperazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AochuangChem-1-(2-Methoxyphenyl)piperazine pictures 2022-10-11 AochuangChem-1-(2-Methoxyphenyl)piperazine
35386-24-4
US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
1-(2-Methoxyphenyl)piperazine pictures 2022-10-10 1-(2-Methoxyphenyl)piperazine
35386-24-4
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
1-(2-Methoxyphenyl)piperazine pictures 2019-07-06 1-(2-Methoxyphenyl)piperazine
35386-24-4
US $1.00 / kg 1kg 99% Customized Career Henan Chemical Co
RARECHEM AH CK 0126 TIMTEC-BB SBB003620 LABOTEST-BB LT00233095 AKOS BBS-00003584 1-(2-METHOXYLPHENYL)-PIPERAZINE 2-(PIPERAZIN-1-YL)METHOXYBENZENE 2-(1-PIPERAZINYL)ANISOLE 1-(O-METHOXYPHENYL)PIPERAZINE 1-(2-Methoxyphenyl)piperazine,98% 1-(2-Methoxyphenyl)piperazine 97% 1-(2-methoxyphenylj-piperazine 1-(2-METHOXYPHENYL) PIPERAZINE BASE ( OMEPPBA ) Piperazine, 1-(2-methoxyphenyl)- 2-MPP 2-Piperazinoanisole 1-(2-Methoxyphenyl)piperazine 1-(o-Anisyl)piperazine 1-[2-(Methyloxy)phenyl]piperazine D 15157 N-(2-Methoxyphenyl)piperazine N-(o-Methoxyphenyl)piperazine 1-(2-Methoxypheny)piperazine 1-(2-Methoxyphenyl)piperazine, 98+% 5GR Urapidil Impurity 6 1-(2-Methoxyphenyl)piperazine> TIANFU-CHEM 35386-24-4 1-(2-Methoxyphenyl)piperazine dihydrogen 1-(2-methoxyphenyl)piperazine dichloride 1-(2-Methoxyphenyl)piperazine, ≥ 98.0% 35386-24-4 35386-24-47 36386-24-4 C11H16N2O Building Blocks Heterocyclic Building Blocks Piperazines Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Bioactive Small Molecules C11 Cell Biology Chemical Synthesis API intermediates (intermediate of urapidil) Building Blocks Heterocyclic Building Blocks Piperazines Piperidines, Piperidones, Piperazines BUILDING BLOCKS Piperaizine Heterocyclic Building Blocks M