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Isobutaneboronic acid

CAS No.
84110-40-7
Chemical Name:
Isobutaneboronic acid
Synonyms
ISOBUTYLBORONIC ACID;(2-METHYLPROPYL)BORONIC ACID;2-Methylpropaneboronic acid;Isobutylboronic;RARECHEM AH PB 0258;FUB-144 fubamb 5fadb;isobutaneboronic acid;1-ISOBUTANEBORONIC ACID;Bortezomib Impurity N17;Isobutylboronic Acid, 95+%
CBNumber:
CB9729575
Molecular Formula:
C4H11BO2
Molecular Weight:
101.94
MDL Number:
MFCD00134156
MOL File:
84110-40-7.mol
Last updated:2024-04-22 15:59:48

Isobutaneboronic acid Properties

Melting point 108-111 °C(lit.)
Boiling point 180.0±23.0 °C(Predicted)
Density 0.910±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Acetonitrile (Slightly), DMSO, Methanol (Slightly)
form Crystalline Powder or Flakes
pka 10.49±0.43(Predicted)
color White to cream
CAS DataBase Reference 84110-40-7(CAS DataBase Reference)
FDA UNII KHX76H7JHZ

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  37/39-26
WGK Germany  3
TSCA  No
HazardClass  IRRITANT
HS Code  29319090
NFPA 704
0
2 0

Isobutaneboronic acid price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 346225 (2-Methylpropyl)boronic acid ≥95.0% 84110-40-7 1g $21.84 2024-03-01 Buy
Sigma-Aldrich 346225 (2-Methylpropyl)boronic acid ≥95.0% 84110-40-7 5g $62.4 2024-03-01 Buy
TCI Chemical I0597 Isobutylboronic Acid (contains varying amounts of Anhydride) 84110-40-7 5g $64 2024-03-01 Buy
TCI Chemical I0597 Isobutylboronic Acid (contains varying amounts of Anhydride) 84110-40-7 25g $254 2024-03-01 Buy
Alfa Aesar H27698 Isobutylboronic acid, 97% 84110-40-7 1g $25.65 2024-03-01 Buy
Product number Packaging Price Buy
346225 1g $21.84 Buy
346225 5g $62.4 Buy
I0597 5g $64 Buy
I0597 25g $254 Buy
H27698 1g $25.65 Buy

Isobutaneboronic acid Chemical Properties,Uses,Production

Description

Isobutaneboronic acid is also known as isobutylboronic acid. Isobutaneboronic acid has been used to synthesize potent and selective dipeptidyl boronic acid proteasome inhibitors, which are promising therapeutics to treat cancer and inflammatory diseases.1

Reference

J. Adams, M. Behnke, S. Chen, A. A. Cruickshank, L. R. Dick, L. Grenier, J. M. Klunder, Y. Ma, L. Plamondon, R. L. Stein, Potent and selective inhibitors of the proteasome: Dipeptidyl boronic acids, Bioorganic & Medicinal Chemistry Letters, 1998, vol. 8, pp. 333-338

Chemical Properties

White to Almost white powder to crystal

Uses

2-Methylpropylboronic Acid is used in the preparation of isocoumarin analogs as inhibitors of γ-secretase cleavage. Also used in the preparation of peptide boronc acid.

Uses

suzuki reaction

Uses

(2-Methylpropyl)boronic acid can be used as:
A reactant in the preparation of 4-isobutylisoquinoline from 4-bromoisoquinoline by Suzuki-Miyaura type couple reaction.
A catalyst along with aluminum hydroxide, boric acid in the polymerization of styrene.
It can also be used as a reactant in:
Copper catalyzed cross-coupling reactions.
The synthesis of polyborylalkanes by Ir-catalyzed C-H borylation reaction.
The preparation of heterosubstituted diazaboroles and borinines.

Global( 403)Suppliers
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Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
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Jinan Finer Chemical Co., Ltd
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View Lastest Price from Isobutaneboronic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Isobutylboronic Acid pictures 2024-04-23 Isobutylboronic Acid
84110-40-7
US $11.00 / KG 1KG 99% 100mt Jinan Finer Chemical Co., Ltd
Isobutylboronic acid pictures 2024-04-22 Isobutylboronic acid
84110-40-7
US $30.00 / kg 1kg 99.7% 200000kg Ouhuang Engineering Materials (Hubei) Co., Ltd
Isobutylboronic Acid pictures 2024-04-22 Isobutylboronic Acid
84110-40-7
US $30.00 / kg 1kg 99% 2000kg hebei hongtan Biotechnology Co., Ltd
2-METHYL-1-PROPYLBORONIC ACID 2-METHYL-1-PROPANEBORONIC ACID 1-ISOBUTANEBORONIC ACID RARECHEM AH PB 0258 Isobutylboronic isobutaneboronic acid ISOBUTYLBORONIC ACID, CONTAINS VARYING AMOUNTS OF ANHYDRIDE 2-Methylprop-1-ylboronic acid (2-Methylpropyl)boronic acid,98% (2-Methylpropyl)boronic acid, 98% 5GR 2-Methyl propyl boroic acid (2-Methylpropyl)boronic acid >=95.0% Isobutylboronic Acid, 95+% Isobutaneboronic acid (2-Methylpropyl)boronic acid Isobutylboronic Acid (contains varying a… Boronic acid, B-(2-methylpropyl)- M**(2-METHYLPROPYL)BORONIC ACID FUB-144 fubamb 5fadb Isobutaneboronic acid, ≥95% Isobutylboronic Acid extrapure, 98% (2-METHYLPROPYL)BORONIC ACID ISOBUTYLBORONIC ACID 2-Methylpropaneboronic acid Bortezomib Impurity N17 84110-40-7 Organometallic Reagents Boronic Acids and Derivatives Alkyl B (Classes of Boron Compounds) Boronic Acids Boronic acids Boron, Nitrile, Thio,& TM-Cpds Organoborons Alkyl B (Classes of Boron Compounds) CHIRAL CHEMICALS bc0001 84110-40-7