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Esomeprazole magnesium trihydrate

CAS No.
217087-09-7
Chemical Name:
Esomeprazole magnesium trihydrate
Synonyms
Nexium;EsomepazoleTrihydrate;Esomeprazole Mg Trihydrate;ESOPMEPRAZOLE MG TRIHYDRATE;EsoMeprazole Meg. Trihydrate;Omeprazole 8.5%/12.5% pellels;Esomeprazole Magnesium (10 mg);Esomeprazole Magnesium (25 mg);Omeprazole Magnesium Trihydrate;EsoMeprazole Magnesiu Trihydrate
CBNumber:
CB9740619
Molecular Formula:
C34H38MgN6O7S2
Molecular Weight:
731.14
MDL Number:
MFCD07698573
MOL File:
217087-09-7.mol
MSDS File:
SDS
Last updated:2024-03-16 07:03:48

Esomeprazole magnesium trihydrate Properties

Melting point 184-189°C (dec.)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility Slightly soluble in water, soluble in methanol, practically insoluble in heptane.
InChI InChI=1S/2C17H18N3O3S.Mg.H2O/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;;/h2*5-8H,9H2,1-4H3;;1H2/q2*-1;+2;
InChIKey VEVZQDGATGBLIC-UHFFFAOYSA-N
SMILES C(C1N=CC(C)=C(OC)C=1C)S1C2[N-]C3=CC(OC)=CC=C3N=2[Mg+2]2(O=S(CC3N=CC(C)=C(OC)C=3C)C3[N-]C4=CC(OC)=CC=C4N2=3)O=1.O
CAS DataBase Reference 217087-09-7(CAS DataBase Reference)
NCI Dictionary of Cancer Terms Nexium
FDA UNII R6DXU4WAY9
NCI Drug Dictionary Nexium

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
HS Code  2933399090

Esomeprazole magnesium trihydrate price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR1585 Esomeprazole Magnesium 217087-09-7 1g $193 2024-03-01 Buy
Sigma-Aldrich 1249789 Esomeprazole magnesium UnitedStatesPharmacopeia(USP)ReferenceStandard 217087-09-7 100MG $483 2024-03-01 Buy
Sigma-Aldrich Y0001028 Esomeprazole magnesium trihydrate European Pharmacopoeia (EP) Reference Standard 217087-09-7 y0001028 $154 2024-03-01 Buy
ChemScene CS-1024 Esomeprazole magnesium trihydrate 217087-09-7 50mg $156 2021-12-16 Buy
ApexBio Technology A3399 Esomeprazole magnesium trihydrate 217087-09-7 50mg $205 2021-12-16 Buy
Product number Packaging Price Buy
PHR1585 1g $193 Buy
1249789 100MG $483 Buy
Y0001028 y0001028 $154 Buy
CS-1024 50mg $156 Buy
A3399 50mg $205 Buy

Esomeprazole magnesium trihydrate Chemical Properties,Uses,Production

Chemical Properties

Off-White Powder

Uses

esomeprazole magnesium trihydrate for the healing of peptic ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.

  1. Zollinger-Ellison syndrome
  2. Peptic ulcer, site unspecified
  3. Duodenal ulcer
  4. Gastric ulcer
  5. Gastro-oesophageal reflux disease
Esomeprazole belongs to the family of medications known as proton pump inhibitors (PPIs). Esomeprazole is registered by the Therapeutic Goods Administration (TGA) for the following indications:
  1. Gastro-Oesophageal Reflux Disease (GORD):
  2. treatment of erosive reflux oesophagitis;
  3. long-term management of patients with healed oesophagitis to prevent relapse;
  4. symptomatic treatment of gastro-oesophageal reflux disease (GORD).
In combination with appropriate antibiotics for:
  1. healing of duodenal ulcer associated with Helicobacter pylori;
  2. eradication of Helicobacter pylori in patients with active or healed peptic ulcer.
  3. Short-term treatment of upper gastrointestinal symptoms associated with non-steroidal anti-inflammatory drug (NSAID) (non-selective and COX-2 selective) therapy.
  4. Healing of gastric ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.
  5. Prevention of gastric and duodenal ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy in patients at risk.

Uses

S-Form of Omeprazole. Gastric proton-pump inhibitor

Uses

Esomeprazole Magnesium Trihydrate is used in preparation of esomeprazole magnesium trihydrate.

brand name

Nexium (AstraZeneca).

Biological Activity

Esomeprazole magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a potent, orally active H+, K+-ATPase inhibitor. Esomeprazole magnesium trihydrate has the potential for upper intestinal disorders and gastroesophageal reflux disease research. Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release by inhibiting V-H+-ATPases.

Esomeprazole magnesium trihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 414)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing Huazhou New Material Co., Ltd.
+8618913378169 howard.wu@chinaredsun.com China 39 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5988 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118 xie@china-sinoway.com China 990 58
Sigma Audley
+86-18336680971 +86-18126314766 nova@sh-teruiop.com China 524 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
Jiangsu Zhongbang Pharmaceutical Co., Ltd.
025-87151996 zbsales@chinaredsun.com CHINA 32 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9354 55
Rixing Chemical CO.,LTD
+86-13237129059 -13237129059 sales@rixingchemi.com CHINA 229 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3012 60
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60

Related articles

View Lastest Price from Esomeprazole magnesium trihydrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Esomeprazole Magnesium Trihydrate pictures 2024-03-26 Esomeprazole Magnesium Trihydrate
217087-09-7
US $0.00 / Kg/Bag 2Kg/Bag 99% up, EP9.0, CEP 20 tons Sinoway Industrial co., ltd.
Esomeprazole magnesium trihydrate pictures 2024-03-16 Esomeprazole magnesium trihydrate
217087-09-7
US $35.00-25.00 / kg 1kg 99.8% 200tons/year Sigma Audley
Esomeprazole magnesium trihydrate pictures 2024-03-16 Esomeprazole magnesium trihydrate
217087-09-7
US $0.00 / KG 100g 98%+ 100kg WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD

Esomeprazole magnesium trihydrate Spectrum

ESOMEPRAZOLE MAGNESIUM TRIHYDRATE bis(5-methoxy-2-[(s)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1h-benzylimidazole-1-yl) magnesium trihydrate (T-4)-Bis[5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolato]magnesium Nexium ESOPMEPRAZOLE MG TRIHYDRATE 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]benzimidazol-1-ide 5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]benzimidazol-1-ide 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide EsoMeprazole Meg. Trihydrate Esomeprazole Magnesium (10 mg) ESOMEPRAZOLE MAGNESIUM TRIHYDRATE USP (S)-OMeprazole MagnesiuM trihydrate MagnesiuM,bis[6-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl-kO]-1H-benziMidazolato-kN3]-, hydrate (1:3), (T-4)- Esomeprazole magnesium trihydrate Bis(5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzylimidazole-1-yl) magnesium trihydrate Esomeprazole Magnesium (25 mg) EsoMeprazole Magnesiu Trihydrate Esomeprazole magnesium thihydrate Magnesium, bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-, hydrate (1:3), (T-4)- Esomeprazole Magnesium Dihydrate/Trihydrate Magnesium,bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-kO]-1H-benzimidazolato-kN3]-, hydrate Esomeprazole agnesium trihydrate Omeprazole Magnesium Trihydrate Esomeprazole magnesium trihydrate CRS Nesomeprazole magnesium trihydrate EsomepazoleTrihydrate Esomeprazole Magnesium (1249789) Omeprazole(Esomeprazole Magnesium) Trihydrate Esomeprazole Magnesium Tri-Hydrate IP/Ph. Eur./BP Omeprazole 8.5%/12.5% pellels Esomeprzole magnesium Trihydrate Esomperazole Magnessium Trihydrate Esomeprazole Mg Trihydrate 217087-09-7 2C17H18N3O3SMg3H2O C34H36MgN6O6S23H2O C34H42MgN6O9S2 71312 Acid pump inhibitors Chiral Reagents Inhibitors Intermediates & Fine Chemicals Pharmaceuticals